Accuracy of noninvasive total haemoglobin measurement for detecting anaemia in infants: a cross-sectional study in a well-child care clinic, Khon Kaen, Thailand
Abstract
Objective Infants are at a high risk of developing anaemia, which can arise from various causes, including inappropriate feeding practices. However, few infants attend anaemia screening programmes due to poor cooperation and being time-consuming. This study evaluated the accuracy of noninvasive total haemoglobin (Hb) spot-check monitoring as part of anaemia screening in healthy infants, compared with the conventional laboratory method. Design A cross-sectional study was conducted using a consecutive sampling technique. Setting The study was carried out at the Well-Child Clinic, Khon Kaen University, Thailand. Participants Healthy, full-term infants aged 6–12 months who were scheduled for vaccination. Spectrophotometric haemoglobin (SpHb) was measured using Masimo Rad-67 with Rainbow DCI-mini Sensor. These values were compared with conventional laboratory analysis (HbLab) performed on the same day. Primary and secondary outcome Differences between Hb values using the two methods were analysed using the Bland–Altman method. Sensitivity, specificity and positive and negative predictive values (PPV and NPV) for detecting anaemia were determined. Anaemia was defined as HbLab of <11.0 g/dL. Results A total of 104 infants, with a median age of 9.6 (IQR 9.3, 10.9) months, were included. The prevalence of anaemia, defined by HbLab, was 38.46%. The mean SpHb was 12.20±1.10 g/dL, while the mean HbLab was 11.19±1.21 g/dL. A moderate positive correlation was observed (r=0.575, p<0.001).…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 104 participants or records.
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