A ratiometric molecularly imprinted electrochemical sensor based on fluorine-doped ferric oxyhydroxide nanorods for highly sensitive detection of carbendazim
Abstract
Background: Electrochemical sensors offer high sensitivity for detecting analytes at ultralow concentrations (nM-pM) but have limited specificity towards target molecules. Nanomaterial modifications are employed to enhance conductivity and catalytic activity. Critically, molecularly imprinted polymers (MIP) provide a solution for specificity by creating selective recognition cavities complementary to the target analyte. Furthermore, dual-signal ratiometric strategies are indispensable to intrinsically correct for matrix effects and environmental fluctuations, ensuring reliable quantification. For the fungicide carbendazim (CBD), crucial for food safety, reliable on-site detection demands overcoming these combined limitations. We thus developed a ratiometric sensor integrating conductivity-enhanced fluorine-doped β-FeOOH nanorods (F-β-FeOOH NRs) with a CBD-specific MIP layer.
Results: A novel ratiometric sensor was fabricated by growing F-β-FeOOH NRs on carbon cloth (CC) via one-step hydrothermal synthesis. F-doping was strategically employed to facilitate the electron transfer and enhance the redox reaction of [Fe(CN)6]3-∕4-. A MIP layer was electropolymerized on F-β-FeOOH NRs/CC using CBD as the template and resorcinol/nicotinamide as dual monomers, thereby creating selective recognition sites. The ratiometric mode utilized the CBD oxidation peak (analyte-specific response) and the internal reference signal from [Fe(CN)6]3-∕4- (internal reference). This dual-signal strategy…
Read the paper
Related studies
- Nano Biosensors: Properties, applications and electrochemical techniques
- Electrochemically Synthesized MIP Sensors: Applications in Healthcare Diagnostics
- Toward a Harmonization for Using in situ Nutrient Sensors in the Marine Environment
- Electrochemical determination of rutin by using NiFe2O4 nanoparticles-loaded reduced graphene oxide
- Application of Polyoxometalate-based composites for sensor systems: A review
- Sensitive Electrochemical and Thermal Detection of Human Noroviruses Using Molecularly Imprinted Polymer Nanoparticles Generated against a Viral Target
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.