A novel near-infrared light-responsive photoelectrochemical platform for detecting microcystin-LR in fish based on Ag2S cubes and plasmonic Au nanoparticles
Abstract
As a main contaminant in fish, microcystin-LR (MC-LR) leads to serious liver problems; therefore, the development of MC-LR sensors is important to guarantee aquatic food safety. In this work, a near-infrared (NIR) light-excited photoelectrochemical (PEC) immunosensor was developed through conjugation of Ag2S cubes with Au nanoparticles (NPs) to determine MC-LR residues in fish. Specifically, as a narrow-band semiconducting material, Ag2S is capable of absorbing NIR light. Taking advantage of the localized surface plasmon resonance (LSPR) effect along with good conductivity of AuNPs, the developed AuNP/Ag2S/fluorine-doped tin oxide (FTO) owns much higher photoelectric conversion efficiency, and the photocurrent is 5.3 times that of Ag2S FTO. Subsequently, the NIR-driven AuNP/Ag2S/FTO was used to immobilize antibodies (Abs) for MC-LR. Their specificity to MC-LR led to steric effects and limited surface electron transfer, causing reduce of the photocurrent. Through AuNP/Ag2S-composite amplification and immunological specificity, the PEC immunosensor can quantitatively measure MC-LR with a wide linear range, 10 pg L-1 to 10 μg L-1, and a much low detection limit, 7 pg L-1 (S/N = 3). Finally, the NIR PEC sensor was employed in the analysis of MC-LR contents in fish. This work reveals the NIR-responsive ability of Ag2S cubes and deepens understanding the role of AuNPs in the PEC process. Due to the superior properties, the developed NIR PEC immunosensor has been demonstrated as a…
Read the paper
Related studies
- Nano Biosensors: Properties, applications and electrochemical techniques
- Electrochemically Synthesized MIP Sensors: Applications in Healthcare Diagnostics
- Toward a Harmonization for Using in situ Nutrient Sensors in the Marine Environment
- Electrochemical determination of rutin by using NiFe2O4 nanoparticles-loaded reduced graphene oxide
- Application of Polyoxometalate-based composites for sensor systems: A review
- Sensitive Electrochemical and Thermal Detection of Human Noroviruses Using Molecularly Imprinted Polymer Nanoparticles Generated against a Viral Target
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.