Molecularly Imprinted Electrochemical Sensors for Halogenated anti-Infective Agent Detection: A Review of Current Developments and Prospects
Abstract
The global struggle against infectious diseases represents a significant health issue that has persisted since ancient eras. Anti-infective agents are compounds that either prevent the spread of infectious pathogens or eradicate them. Halogens play a crucial role in the discovery and development of pharmaceuticals, as they are integral to synthesizing numerous drugs and medicinal compounds. These elements are vital across various categories of anti-infective agents and are found in many approved medications and promising lead compounds currently undergoing testing. The precise and swift identification of halogenated anti-infective agents is essential for clinical surveillance, food safety, and environmental research. Molecularly imprinted polymers (MIPs) have surfaced as a valuable resource for detecting these agents owing to their exceptional specificity, sensitivity, cost-effectiveness, and mobility. This review presents an extensive examination of the latest developments in the application of MIPs for detecting anti-infective agents. Despite the existing challenges, MIPs offer an economical and portable detection solution appropriate for on-site investigation across various fields. This review examines the fundamental operating principles, fabrication techniques, materials, and methodologies associated with MIPs. The following section delves into MIP-based sensors for precisely quantifying halogenated anti-infective agents across various sample types. Lastly, the review…
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