Usefulness of X-rays in the Differential Diagnosis of Hypophosphataemic Rickets
Abstract
Rickets and osteomalacia are two related conditions linked by the lack of mineralization of bone tissue due to a disturbance of calcium and phosphate homeostasis. Some of the most characteristic features of rickets are skeletal deformities, fractures, linear and continuous periosteal reaction, and enlargement of the metaphyseal space in an irregular and frayed form. However, these radiological findings are not exclusive to these diseases, but may also originate in children who were born prematurely or in those who have suffered physical abuse or an accident. Hence, it is important to establish a differential diagnosis. All these observations can be evidenced by radiological images using a simple X-ray. The aim of this article is to show the main radiological findings that can be found in rickets and how to establish a differential diagnosis of X-linked hypophosphataemic (XLH) rickets.
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