Browse studies, page 1139
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- Results from the Survey of Antibiotic Resistance (SOAR) 2016–18 in Vietnam, Cambodia, Singapore and the Philippines: data based on CLSI, EUCAST (dose-specific) and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints Journal of Antimicrobial Chemotherapy, 2020
- Harnessing Hybrid Niosomes for Improved Oral Bioavailability of an Anticoagulant: Design, Optimization and In-Vivo Pharmacokinetics and Pharmacodynamics Evaluations AAPS PharmSciTech, 2026
- Experimental, DFT, molecular docking and in silico ADMET studies of cadmium-benzenetricarboxylates Eclética Química, 2022
- Comprehensive Pharmacokinetic Evaluation of High Melanin Binder Levofloxacin in Rabbits Shows Potential of Topical Eye Drops for Posterior Segment Treatment Investigative Ophthalmology & Visual Science, 2024
- Results from the Survey of Antibiotic Resistance (SOAR) 2015–17 in Turkey: data based on CLSI, EUCAST (dose-specific) and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints Journal of Antimicrobial Chemotherapy, 2020
- Population Pharmacokinetics and Bayesian Dose Adjustment to Advance TDM of Anti-TB Drugs Clinical Pharmacokinetics, 2021
- Amphotericin B- and Levofloxacin-Loaded Chitosan Films for Potential Use in Antimicrobial Wound Dressings: Analytical Method Development and Its Application Pharmaceutics, 2022
- Inclusion of a Phytomedicinal Flavonoid in Biocompatible Surface-Modified Chylomicron Mimic Nanovesicles with Improved Oral Bioavailability and Virucidal Activity: Molecular Modeling and Pharmacodynamic Studies Pharmaceutics, 2022
- Deposition of Inhaled Levofloxacin in Cystic Fibrosis Lungs Assessed by Functional Respiratory Imaging Pharmaceutics, 2021
- Development of Computational In Silico Model for Nano Lipid Carrier Formulation of Curcumin Molecules, 2023
- Capsaicin, a novel inhibitor of the NorA efflux pump, reduces the intracellular invasion of Staphylococcus aureus Journal of Antimicrobial Chemotherapy, 2012
- Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antibacterial Agents: A Review Clinical Pharmacokinetics, 2020
- Prediction of the pharmacokinetics and pharmacodynamics of topiroxostat in humans by integrating the physiologically based pharmacokinetic model with the drug-target residence time model Biomedicine & Pharmacotherapy, 2019
- Pharmacokinetic aspects of retinal drug delivery Progress in Retinal and Eye Research, 2016
- A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis European Respiratory Journal, 2017
- Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies Frontiers in Pharmacology, 2022
- Pharmacokinetics, Pharmacodynamics, and Dose Optimization of Cefiderocol during Continuous Renal Replacement Therapy Clinical Pharmacokinetics, 2021
- Oleocanthal as a Multifunctional Anti-Cancer Agent: Mechanistic Insights, Advanced Delivery Strategies, and Synergies for Precision Oncology International journal of molecular sciences, 2025
- In Silico Screening and Analysis of Broad-Spectrum Molecular Targets and Lead Compounds for Diarrhea Therapy Bioinformatics and biology insights, 2019
- Insights into the evolutionary trajectories of fluoroquinolone resistance in Streptococcus pneumoniae The Journal of antimicrobial chemotherapy, 2015
- Enhancing antibacterial efficacy through macrocyclic host complexation of fluoroquinolone antibiotics for overcoming resistance Scientific reports, 2024
- 8-octyl berberine combats Staphylococcus aureus by preventing peptidoglycan synthesis European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023
- New Potential Pharmacological Targets of Plant-Derived Hydroxyanthraquinones from Rubia spp Molecules (Basel, Switzerland), 2022
- Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening Journal of chemical information and modeling, 2014
- Pharmacokinetic considerations and efficacy of levofloxacin in an inhalational anthrax (postexposure) rhesus monkey model Antimicrobial agents and chemotherapy, 2006
- Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms Nature communications, 2021
- Discovery of psoralen as a quorum sensing inhibitor suppresses Pseudomonas aeruginosa virulence Applied microbiology and biotechnology, 2024
- Pharmacodynamic evaluation of i.v. antimicrobials against Pseudomonas aeruginosa samples collected from U.S. hospitals American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011
- Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa Chinese medicine, 2021
- Computational and Preclinical Prediction of the Antimicrobial Properties of an Agent Isolated from Monodora myristica: A Novel DNA Gyrase Inhibitor Molecules (Basel, Switzerland), 2023
- Efficacy of High Doses of Levofloxacin in Experimental Foreign-Body Infection by Methicillin-Susceptible Staphylococcus aureus Antimicrobial Agents and Chemotherapy, 2006
- In vitro pharmacodynamic activity of gatifloxacin, gemifloxacin, moxifloxacin and levofloxacin against Streptococcus pneumoniae containing specific mutations in DNA gyrase and topoisomerase IV. Diagnostic Microbiology and Infectious Disease, 2003
- Pharmacodynamics of gatifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model: impact of area under the curve/MIC ratios on eradication Antimicrobial Agents and Chemotherapy, 2002
- Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model International Journal of Antimicrobial Agents, 2005
- In Vitro Pharmacodynamic Activities of ABT-492, a Novel Quinolone, Compared to Those of Levofloxacin against Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis Antimicrobial Agents and Chemotherapy, 2003
- Linezolid, levofloxacin, and vancomycin against vancomycin-tolerant and fluoroquinolone-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, 2003
- In Vitro Pharmacodynamic Evaluation of the Mutant Selection Window Hypothesis Using Four Fluoroquinolones against Staphylococcus aureus Antimicrobial Agents and Chemotherapy, 2003
- Levofloxacin plus Metronidazole Administered Once Daily versus Moxifloxacin Monotherapy against a Mixed Infection of Escherichia coli and Bacteroides fragilis in an In Vitro Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2005
- Fluoroquinolone Resistance in Anaerobic Bacteria following Exposure to Levofloxacin, Trovafloxacin, and Sparfloxacin in an In Vitro Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2001
- Comparative pharmacodynamics of moxifloxacin and levofloxacin in an in vitro dynamic model: prediction of the equivalent AUC/MIC breakpoints and equiefficient doses Journal of Antimicrobial Chemotherapy, 2000
- Optimizing Antimicrobial Drug Dosing in Critically Ill Patients Microorganisms, 2021
- Development of an amoxicillin-radix scutellaria extract formulation and evaluation of its pharmacokinetics in pigs BMC veterinary research, 2023
- From genes to clinical management: A comprehensive review of long QT syndrome pathogenesis and treatment Heart rhythm O2, 2024
- On-Demand Drug Delivery Systems Using Nanofibers Nanomaterials (Basel, Switzerland), 2021
- Microneedles as a Promising Technology for Disease Monitoring and Drug Delivery: A Review ACS materials Au, 2025
- Infant Exposure to Antituberculosis Drugs via Breast Milk and Assessment of Potential Adverse Effects in Breastfed Infants: Critical Review of Data Pharmaceutics, 2023
- Update in tuberculosis treatment: a scoping review of current practices Breathe (Sheffield, England), 2025
- A Literature Review on the Impact of the Gut Microbiome on Cancer Treatment Efficacy, Disease Evolution and Toxicity: The Implications for Hematological Malignancies Journal of clinical medicine, 2025
- Deciphering the Intricate Interplay in the Framework of Antibiotic-Drug Interactions: A Narrative Review Antibiotics (Basel, Switzerland), 2024
- Drug-induced liver injury in inflammatory bowel disease: Challenges in diagnosis and monitoring World journal of hepatology, 2025
- Inflammation-Responsive Hydrogels in Perioperative Pain and Wound Management: Design Strategies and Emerging Potential Gels (Basel, Switzerland), 2025
- Advancement of Nanofibrous Mats and Common Useful Drug Delivery Applications Advances in pharmacological and pharmaceutical sciences, 2022
- Optimizing Pyrazinamide Use: A Low-Hanging Fruit in Improving Outcomes with Tuberculous Meningitis? Narrative Review Infectious diseases and therapy, 2025
- Dual-Drug Delivery Systems Using Hydrogel-Nanoparticle Composites: Recent Advances and Key Applications Gels (Basel, Switzerland), 2025
- Overcoming the drug resistance barrier: progress in fosfomycin combination therapy against multidrug-resistant pathogens Frontiers in microbiology, 2025
- Aerosolized delivery resulting in high polymyxin B concentration levels in epithelial lining fluid ensures efficacy in ventilator-associated pneumonia JAC-antimicrobial resistance, 2025
- Sitafloxacin pharmacokinetics/pharmacodynamics against multidrug-resistant bacteria in a dynamic urinary tract infection in vitro model The Journal of antimicrobial chemotherapy, 2022
- Pharmacokinetics of levofloxacin in Japanese quails (Coturnix japonica) following intravenous and oral administration British poultry science, 2012
- In vitro activity of Brucella melitensis isolates to various antimicrobials in Turkey Infectious diseases (London, England), 2015
- In Vitro Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin Antimicrobial agents and chemotherapy, 2017
- In vitro evaluation of antimicrobial resistance selection in Neisseria gonorrhoeae International journal of antimicrobial agents, 2021
- Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa Antimicrobial resistance and infection control, 2020
- Safety of levofloxacin as an antibiotic prophylaxis in the induction phase of children newly diagnosed with acute lymphoblastic leukemia: an interim analysis of a randomized, open-label trial in Brazil Brazilian Journal of Infectious Diseases, 2023
- Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: A Randomized Controlled Trial American Journal of Gastroenterology, 2022
- Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor Fenebrutinib (GDC‐0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial Arthritis & Rheumatology, 2021
- QT effects of bedaquiline, delamanid or both in patients with rifampicin-resistant-TB: a randomized controlled trial Lancet. Infectious Diseases (Print), 2021
- Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Luseogliflozin Dosing in Healthy Japanese Males: A Randomized, Single-Blind, Placebo-Controlled Trial Advances in Therapy, 2014
- Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial Journal of Investigative and Clinical Dentistry, 2015
- A phase 3 active-controlled trial of liposomal bupivacaine via sciatic nerve block in the popliteal fossa after bunionectomy Journal of clinical anesthesia, 2024
- An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study) American Journal of Respiratory and Critical Care Medicine, 2022
- FRI0084 safety, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of rozibafusp alfa in subjects with rheumatoid arthritis: interim analysis of a phase 1B randomized, placebo-controlled, multiple ascending dose clinical trial Annals of the Rheumatic Diseases, 2020
- A randomized controlled trial of levofloxacin, terazosin, and combination therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome International Urology and Nephrology, 2015
- A Phase 3 Active-Controlled Trial of Liposomal Bupivacaine via Adductor Canal Block for Total Knee Arthroplasty Journal of Arthroplasty, 2025
- Effect of preoperative prophylactic antibiotic use on postoperative infection after percutaneous nephrolithotomy in patients with negative urine culture: a single-center randomized controlled trial World journal of urology, 2023
- Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients with Acute Myocardial Infarction (IMPRESSION): study protocol for a randomized controlled trial Trials, 2015
- First-in-Human, Phase 1, Randomized, Double-Blind, Placebo-Controlled Study of TNX-1500, an Fc-Modified anti-CD154 Monoclonal Antibody, Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single-Ascending Doses in Healthy Adults Journal of Clinical Immunology, 2026
- AZD8630/AMG 104, an inhaled anti-thymic stromal lymphopoietin antibody fragment, for moderate-to-severe asthma: Phase 1 randomized controlled trial Journal of Allergy and Clinical Immunology, 2026
- Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women PLoS ONE, 2018
- Lack of improvement after short‐term topical antistaphylococcal endolysin SA.100 therapy in patients with mild‐to‐moderate atopic dermatitis: Results from a randomized, vehicle‐controlled trial British Journal of Clinical Pharmacology, 2026
- Design of CONQUEST, a novel, randomized, placebo-controlled, Phase 2b platform clinical trial to investigate new treatments for patients with early active systemic sclerosis with interstitial lung disease Journal of Scleroderma and Related Disorders, 2024
- Ten-Day Quadruple Therapy Comprising Proton Pump Inhibitor, Bismuth, Tetracycline, and Levofloxacin is More Effective than Standard Levofloxacin Triple Therapy in the Second-Line Treatment of Helicobacter pylori Infection: A Randomized Controlled Trial American Journal of Gastroenterology, 2017
- The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive—A randomized controlled trial British Journal of Clinical Pharmacology, 2020
- Epidural administration of ropivacaine and its effects on the pharmacodynamics of rocuronium: Randomized controlled trial. Interaction between ropivacaine and rocuronium Saudi Journal of Anaesthesia, 2020
- Safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of a novel anti-TSLP bispecific antibody (GR2002) in healthy Chinese adults: a randomized, placebo-controlled phase 1 trial European Journal of Pharmaceutical Sciences, 2026
- Pharmacokinetics and pharmacodynamics of intranasal remimazolam—a randomized controlled clinical trial European Journal of Clinical Pharmacology, 2020
- Efficacy and Safety of Combined Isoniazid-Rifampicin-Pyrazinamide-Levofloxacin Dry Powder Inhaler in Treatment of Pulmonary Tuberculosis: A Randomized Controlled Trial Pulmonary Pharmacology & Therapeutics, 2021
- Safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 685509, a soluble guanylyl cyclase activator, in healthy volunteers: Results from two randomized controlled trials Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Pharmacokinetics, pharmacodynamics, safety and tolerability of FTP-198, a novel, selective autotaxin inhibitor, in healthy subjects: a phase I randomized placebo-controlled trial European Journal of Pharmaceutical Sciences, 2023
- Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in Patients with Parkinson’s Disease and a GBA Mutation: Results from Part 1 of the Randomized, Double-Blinded, Placebo-Controlled MOVES-PD Trial Journal of Parkinson's Disease, 2021
- The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and dose-escalation phase I trial Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT‐4202), an Allosteric Activator of Pyruvate Kinase‐R, in Healthy Adults: A Randomized, Placebo‐Controlled, Double‐Blind, First‐in‐Human Phase 1 Trial Clinical pharmacology in drug development, 2022
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Positive Modulator of HGF/MET, Fosgonimeton, in Healthy Volunteers and Subjects with Alzheimer’s Disease: Randomized, Placebo-Controlled, Double-Blind, Phase I Clinical Trial Journal of Alzheimer's Disease, 2022
- Levofloxacin+Tetracycline Quadruple Regimen for Eradication of Helicobacter pylori: A Multicenter Multinational Randomized Controlled Trial Middle East Journal of Digestive Diseases, 2023
- Riluzole in Spinal Cord Injury Study (RISCIS)–Pharmacokinetic (PK) Sub-Study: An Analysis of Pharmacokinetics, Pharmacodynamics, and Impact on Axonal Degradation of Riluzole in Patients With Traumatic Cervical Spinal Cord Injury Enrolled in the RISCIS Phase III Randomized Controlled Trial Journal of Neurotrauma, 2023
- OP20 Results from the STENOVA trial: A Phase 2a, randomized, placebo-controlled, double-blind study to assess the safety, pharmacokinetics (PK), and pharmacodynamics of ontunisertib (AGMB-129) in patients with Fibrostenotic Crohn’s Disease (FSCD) Journal of Crohn's & Colitis, 2026
- Pharmacokinetics/pharmacodynamics of benralizumab in chronic rhinosinusitis with nasal polyps: Phase III, randomized, placebo‐controlled OSTRO trial British Journal of Clinical Pharmacology, 2024
- Safety, pharmacokinetics, and preliminary pharmacodynamics of 1% and 3% diclofenac vaginal hydrogel for the treatment of primary dysmenorrhea: a randomized, placebo controlled trial Journal of Endometriosis and Pelvic Pain Disorders, 2025
- TTP7.07 Levofloxacin based therapy vs Hybrid therapy in the eradication of Helicobacter pylori : A randomized controlled trial British Journal of Surgery, 2025
- Eye drops and eye gels of levofloxacin: comparison of ocular absorption characterizations and therapeutic effects in the treatment of bacterial keratitis in rabbits Drug Development and Industrial Pharmacy, 2020
- Pharmacokinetics, urinary excretion and milk penetration of levofloxacin in lactating goats Journal of Veterinary Pharmacology and Therapeutics, 2008
