Browse studies, page 1146

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Doxycycline post exposure prophylaxis could theoretically select for resistance to various antimicrobials in 19 pathobionts: an in silico analysis International Journal of Infectious Diseases, 2024
In silico Analysis to Search for an Alternative Inhibitor of Biofilm Production by Helicobacter pylori Current Drug Discovery Technologies, 2025
Exploring Novel Tetrahydropyrimidine and Fused Pyrimidine-Based Compounds as DHFR Inhibitors and Antimicrobial Agents: Synthesis, In Vitro, In Vivo, and In Silico Studies Drug development research (Print), 2025
In silico trials using Monte Carlo simulation to evaluate ciprofloxacin and levofloxacin dosing in critically ill patients receiving prolonged intermittent renal replacement therapy Renal Replacement Therapy, 2016
Exploring the potential role of GyrA inhibiting quinoline analog: an in silico study Scientific Reports, 2025
TiO₂-modified activated carbon for pharmaceutical contaminant removal: experimental and in-silico insights using density functional theory Journal of Environmental Health Science and Engineering, 2025
Prediction and mechanism of combined toxicity of surfactants and antibiotics in aquatic environment based on in silico method Journal of Hazardous Materials, 2025
Microwave-assisted synthesis and in vitro and in silico studies of pyrano[3,2-c]quinoline-3-carboxylates as dual acting anti-cancer and anti-microbial agents and potential topoisomerase II and DNA-gyrase inhibitors RSC Advances, 2025
The Effects of P‐glycoprotein Modulators on the Transition of Levofloxacin to Rat Brain, Testicle, and Plasma: In Vivo and In Silico Studies ChemistrySelect, 2021
The application of in silico experimental model in the assessment of ciprofloxacin and levofloxacin interaction with main SARS-CoV-2 targets: S-, E- and TMPRSS2 proteins, RNA-dependent RNA polymerase and papain-like protease (PLpro)-preliminary molecular docking analysis Pharmacological Reports, 2021
In Silico Evaluation of Doxorubicin and Levofloxacin as Multi-Isoform PI3K Inhibitors: Molecular Docking, Molecular Dynamics Simulations, and MM/PBSA Analysis Bulletin of Pharmaceutical Sciences Assiut University, 2026
Levofloxacin and sulfa drugs linked via Schiff bases: Exploring their urease inhibition, enzyme kinetics and in silico studies Journal of Molecular Structure, 2021
In Silico Activity Prediction and Docking Studies of the Binding Mechanisms of Levofloxacin Structure Derivatives to Active Receptor Sites of Bacterial Type IIA Topoisomerases Scientia Pharmaceutica, 2023
In Silico Molecular Docking, Synthesis and Preliminary Evaluation of Antibacterial Activity of Levofloxacin Carboxamides with Certain Amino Acids Al Mustansiriyah Journal of Pharmaceutical Sciences, 2023
Novel Fluoroquinolones with Possible Antibacterial Activity in Gram-Negative Resistant Pathogens: In Silico Drug Discovery Molecules (Basel, Switzerland), 2023
Montelukast treats Streptococcus pneumoniae-induced sepsis via antibacterial and anti-inflammatory activities Microbiology spectrum, 2025
Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents Scientific reports, 2025
Structural characterization, derivatization, and bioactivities of secondary metabolites produced by termite-associated Streptomyces lannensis BYF-106 Microbiology spectrum, 2025
Synergistic Effects of Pyrrosia lingua Caffeoylquinic Acid Compounds with Levofloxacin Against Uropathogenic Escherichia coli: Insights from Molecular Dynamics Simulations, Antibiofilm, and Antimicrobial Assessments Molecules (Basel, Switzerland), 2024
Bioinformatics Analysis of the Anti-Inflammatory Mechanism and Potential Therapeutic Efficacy of Kezimuke granules in Treating Urinary Tract Infections by Inhibiting NLRP3 Inflammasome Activation International journal of molecular sciences, 2025
Natural Inhibitors of Salmonella MDR Efflux Pumps AcrAB and AcrD: An Integrated In Silico, Molecular, and In Vitro Investigation International journal of molecular sciences, 2024
Discovery of novel uridine-based chitin synthase inhibitors: Design, synthesis and structure-activity relationships Pest management science, 2026
Multimodal computational discovery of MvfR inhibitors targeting quorum sensing in multi-drug-resistant Pseudomonas aeruginosa Scientific reports, 2026
Design, Synthesis, and Anti-Biofilm Activity of C-28 Modified Betulinic Acid Derivatives Targeting SarA in Drug-Resistant Staphylococcus aureus Microorganisms, 2026
R5 and R7 positions on fluoroquinolone scaffolds drive F-actin filament disruption Scientific reports, 2026
Exploration of pyrazole-based pyridine-4-carbohydrazide derivatives as drug-resistant Mtb agents: design, synthesis, biological evaluation, and in-silico studies Future medicinal chemistry, 2025
Molecular diversity and evolutionary dynamics of phage receptor binding proteins in Staphylococcus aureus: implications for phage therapy and resistance Scientific reports, 2026
Synthesis, antibacterial evaluation, and DNA gyrase inhibition profile of some new quinoline hybrids Archiv der Pharmazie, 2019
Genomic and epidemiological characterization of a blaCTX-M-27-carrying ST34 Salmonella enterica serotype Typhimurium in China Journal of global antimicrobial resistance, 2024
Therapeutic potential activity of quercetin complexes against Streptococcus pneumoniae Scientific reports, 2024
Comparative molecular profiling of multidrug-resistant Pseudomonas aeruginosa identifies novel mutations in regional clinical isolates from South India JAC-antimicrobial resistance, 2024
Antimicrobial Resistance in Clinical Ureaplasma spp. and Mycoplasma hominis and Structural Mechanisms Underlying Quinolone Resistance Antimicrobial agents and chemotherapy, 2020
Molecular Interactions of Fluoroquinolone Antibiotics with Lipid Membranes Langmuir : the ACS journal of surfaces and colloids, 2026
In silico discovery of druggable targets in Citrobacter koseri using echinoderm metabolites and molecular dynamics simulation Scientific reports, 2024
Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana Scientific reports, 2019
VIVO complexes with antibacterial quinolone ligands and their interaction with serum proteins Dalton transactions (Cambridge, England : 2003), 2018
Molecular determinants of the bacterial resistance to fluoroquinolones: a computational study Current computer-aided drug design, 2013
In Silico Screening and In Vitro Assessment of Natural Products with Anti-Virulence Activity against Helicobacter pylori Molecules (Basel, Switzerland), 2021
Characteristics of a Carbapenem-Resistant Acinetobacter baumannii Strain Causing Community-Acquired Pneumonia in a Young Healthy Women Infection and drug resistance, 2023
Mechanistic study of the electrochemical oxidation of fluoroquinolones: Ciprofloxacin, danofloxacin, enoxacin, levofloxacin and lomefloxacin Chemosphere, 2024
Levofloxacin alleviates blood-brain barrier disruption following cerebral ischemia and reperfusion via directly inhibiting A-FABP. European journal of pharmacology, 2024
Design, synthesis, molecular docking, anti-Proteus mirabilis and urease inhibition of new fluoroquinolone carboxylic acid derivatives Bioorganic chemistry, 2017
Phylogenic analysis of coronavirus genome and molecular studies on potential anti-COVID-19 agents from selected FDA-approved drugs Journal of biomolecular structure & dynamics, 2022
Estimation of country-specific tuberculosis resistance antibiograms using pathogen genomics and machine learning BMJ global health, 2024
In silico and in vitro genotoxicity evaluation of descarboxyl levofloxacin, an impurity in levofloxacin Drug and chemical toxicology, 2014
Homology modeling, molecular dynamics, and virtual screening of NorA efflux pump inhibitors of Staphylococcus aureus Drug design, development and therapy, 2016
Study of andrographolide bioactivity against Pseudomonas aeruginosa based on computational methodology and biochemical analysis Frontiers in chemistry, 2024
Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach British journal of clinical pharmacology, 2016
Identification and Antibiotic Profiling of Wohlfahrtiimonas chitiniclastica, an Underestimated Human Pathogen Frontiers in microbiology, 2021
Interaction of levofloxacin with lung surfactant at the air-water interface Colloids and surfaces. B, Biointerfaces, 2017
Could Respiratory Fluoroquinolones, Levofloxacin and Moxifloxacin, Prove to be Beneficial as an Adjunct Treatment in COVID-19? Archives of medical research, 2020
Drug Repurposing Based on Protozoan Proteome: In Vitro Evaluation of In Silico Screened Compounds against Toxoplasma gondii Pharmaceutics, 2022
Ab initio molecular dynamics simulations and experimental speciation study of levofloxacin under different pH conditions Physical chemistry chemical physics : PCCP, 2021
Molecular epidemiology and antibiotic resistance profiling of Staphylococcus aureus isolates from camel mastitis Microbial pathogenesis, 2025
Analytical profiling of mutations in quinolone resistance determining region of gyrA gene among UPEC. PloS one, 2018
Population pharmacokinetics of oral levofloxacin in healthy volunteers and dosing optimization for multidrug-resistant tuberculosis therapy Biopharmaceutics & drug disposition, 2021
An association study of HLA with levofloxacin-induced severe cutaneous adverse drug reactions in Han Chinese iScience, 2023
Prediction of Antimicrobial Resistance in Gram-Negative Bacteria From Whole-Genome Sequencing Data Frontiers in microbiology, 2020
Parallel-slipped π-π electron-donor-acceptor in adsorption process: Molecular dynamics simulation Journal of molecular graphics & modelling, 2022
An experimental in silico study on COVID-19: Response of neutrophil-related genes to antibiotics Health science reports, 2022
Synthesis and molecular docking study of some 3,4-dihydrothieno[2,3-d]pyrimidine derivatives as potential antimicrobial agents Bioorganic chemistry, 2019
Isolation and Characterization of Werneria Chromene and Dihydroxyacidissimol from Burkillanthus malaccensis (Ridl.) Swingle Plants (Basel, Switzerland), 2022
Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients Scientific reports, 2022
Molecular detection of H. pylori antibiotic-resistant genes and molecular docking analysis FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020
Antibacterial Potential of Novel Acetamide Derivatives of 2-Mercaptobenzothiazole: Synthesis and Docking Studies ACS omega, 2023
Integrative analysis of levofloxacin-induced liver injury: Insights from pharmacovigilance, human liver organoids, and extracellular vesicle proteomics Toxicology and applied pharmacology, 2025
Levofloxacin in Bone and Joint Infections: Development of an Application for Model-Informed Precision Dosing Clinical pharmacology and therapeutics, 2026
In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosis Scientific reports, 2022
The effects of levofloxacin on rabbit fibroblast-like synoviocytes in vitro Toxicology and Applied Pharmacology, 2012
In vitro activity of levofloxacin against contemporary clinical isolates of Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae from North America and Europe Clinical Microbiology and Infection, 2002
In vitro activity of levofloxacin against gram-positive bacteria Chemotherapy, 1999
Comparative In Vitro Activities of Linezolid, Telithromycin, Clarithromycin, Levofloxacin, Moxifloxacin, and Four Conventional Antimycobacterial Drugs against Mycobacterium kansasii Antimicrobial Agents and Chemotherapy, 2004
In vitro activities of levofloxacin used alone and in combination with first- and second-line antituberculous drugs against Mycobacterium tuberculosis Antimicrobial Agents and Chemotherapy, 1996
Levofloxacin and ciprofloxacin in vitro activities against 4,003 clinical bacterial isolates collected in 24 Italian laboratories Antimicrobial Agents and Chemotherapy, 2003
Comparative bactericidal activities of ciprofloxacin, clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Streptococcus pneumoniae in a dynamic in vitro model Antimicrobial Agents and Chemotherapy, 2001
In-vitro activity of ofloxacin, levofloxacin and D-ofloxacin against staphylococci Journal of Antimicrobial Chemotherapy, 1996
In vitro activity of linezolid in combination with doxycycline, fosfomycin, levofloxacin, rifampicin and vancomycin against methicillin-susceptible Staphylococcus aureus PubMed, 2006
Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models Acta Ophthalmologica, 2010
Activities of Mutant Prevention Concentration-Targeted Moxifloxacin and Levofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2003
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram- positive and gram-negative pathogens from respiratory tract infections Journal of Antimicrobial Chemotherapy, 1997
Phenotypic Resistance of Staphylococcus aureus , Selected Enterobacteriaceae , and Pseudomonas aeruginosa after Single and Multiple In Vitro Exposures to Ciprofloxacin, Levofloxacin, and Trovafloxacin Antimicrobial Agents and Chemotherapy, 2001
Pharmacodynamics of moxifloxacin and levofloxacin against Staphylococcus aureus and Staphylococcus epidermidis in an in vitro pharmacodynamic model Clinical Infectious Diseases, 2001
In Vitro Pharmacodynamics of Levofloxacin and Other Aerosolized Antibiotics under Multiple Conditions Relevant to Chronic Pulmonary Infection in Cystic Fibrosis Antimicrobial Agents and Chemotherapy, 2009
Pharmacodynamics of levofloxacin, ofloxacin, and ciprofloxacin, alone and in combination with rifampin, against methicillin-susceptible and -resistant Staphylococcus aureus in an in vitro infection model Antimicrobial Agents and Chemotherapy, 1994
Inhibitory and bactericidal activities of levofloxacin against Mycobacterium tuberculosis in vitro and in human macrophages Antimicrobial Agents and Chemotherapy, 1994
Effects of NorA Inhibitors on In Vitro Antibacterial Activities and Postantibiotic Effects of Levofloxacin, Ciprofloxacin, and Norfloxacin in Genetically Related Strains of Staphylococcus aureus Antimicrobial Agents and Chemotherapy, 1999
Biopharmaceutical characterization of oral immediate release drug products. In vitro/in vivo comparison of phenoxymethylpenicillin potassium, glimepiride and levofloxacin European Journal of Pharmaceutics and Biopharmaceutics, 1998
Comparative in vitro activity of gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin and trovafloxacin against 4151 Gram-negative and Gram-positive organisms International Journal of Antimicrobial Agents, 2000
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis Antimicrobial Agents and Chemotherapy, 1995
Inhibitory effects of the quinolone antibiotics trovafloxacin, ciprofloxacin, and levofloxacin on osteoblastic cells in vitro Journal of Orthopaedic Research®, 2000
Comparison of toxicities of moxifloxacin, cefuroxime, and levofloxacin to corneal endothelial cells in vitro Journal of cataract and refractive surgery, 2014
Formulation and in vitro evaluation of size expanding gastro-retentive systems of levofloxacin hemihydrate International journal of pharmaceutics, 2014
In vitro evaluation of tigecycline synergy testing with nine antimicrobial agents against Enterobacter cloacae clinical strains Frontiers in Microbiology, 2024
Potential effectiveness of parenteral nemonoxacin in the treatment of Clostridioides difficile infections: in vitro, ex vivo, and mouse studies Frontiers in Microbiology, 2024
Cannabidiol Demonstrates Remarkable Efficacy in Treating Multidrug-Resistant Enterococcus Faecalis Infections In Vitro and In Vivo TRENDS IN THE SCIENCES, 2024
Comparative in vitro activity of Delafloxacin and other antimicrobials against isolates from patients with acute bacterial skin, skin-structure infection and osteomyelitis Brazilian Journal of Infectious Diseases, 2024
Levofloxacin: formulation and in-vitro evaluation of alginate and chitosan nanospheres Egyptian Pharmaceutical Journal, 2015
Increased in vitro antimicrobial resistance of Mycoplasma pneumoniae isolates obtained from children in Beijing, China, in 2023 Frontiers in Cellular and Infection Microbiology, 2024
Comparative in vitro activity of ciprofloxacin and levofloxacin against isolated uropathogens in Ghana: a pilot study The Pan African Medical Journal, 2018
Efficacy of levofloxacin against biofilms of Pseudomonas aeruginosa isolated from patients with respiratory tract infections in vitro MicrobiologyOpen, 2018