Browse studies, page 1178
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- Safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 685509, a soluble guanylyl cyclase activator, in healthy volunteers: Results from two randomized controlled trials Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Pharmacokinetics, pharmacodynamics, safety and tolerability of FTP-198, a novel, selective autotaxin inhibitor, in healthy subjects: a phase I randomized placebo-controlled trial European Journal of Pharmaceutical Sciences, 2023
- Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in Patients with Parkinson’s Disease and a GBA Mutation: Results from Part 1 of the Randomized, Double-Blinded, Placebo-Controlled MOVES-PD Trial Journal of Parkinson's Disease, 2021
- The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and dose-escalation phase I trial Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT‐4202), an Allosteric Activator of Pyruvate Kinase‐R, in Healthy Adults: A Randomized, Placebo‐Controlled, Double‐Blind, First‐in‐Human Phase 1 Trial Clinical pharmacology in drug development, 2022
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Positive Modulator of HGF/MET, Fosgonimeton, in Healthy Volunteers and Subjects with Alzheimer’s Disease: Randomized, Placebo-Controlled, Double-Blind, Phase I Clinical Trial Journal of Alzheimer's Disease, 2022
- Levofloxacin+Tetracycline Quadruple Regimen for Eradication of Helicobacter pylori: A Multicenter Multinational Randomized Controlled Trial Middle East Journal of Digestive Diseases, 2023
- Riluzole in Spinal Cord Injury Study (RISCIS)–Pharmacokinetic (PK) Sub-Study: An Analysis of Pharmacokinetics, Pharmacodynamics, and Impact on Axonal Degradation of Riluzole in Patients With Traumatic Cervical Spinal Cord Injury Enrolled in the RISCIS Phase III Randomized Controlled Trial Journal of Neurotrauma, 2023
- OP20 Results from the STENOVA trial: A Phase 2a, randomized, placebo-controlled, double-blind study to assess the safety, pharmacokinetics (PK), and pharmacodynamics of ontunisertib (AGMB-129) in patients with Fibrostenotic Crohn’s Disease (FSCD) Journal of Crohn's & Colitis, 2026
- Pharmacokinetics/pharmacodynamics of benralizumab in chronic rhinosinusitis with nasal polyps: Phase III, randomized, placebo‐controlled OSTRO trial British Journal of Clinical Pharmacology, 2024
- Safety, pharmacokinetics, and preliminary pharmacodynamics of 1% and 3% diclofenac vaginal hydrogel for the treatment of primary dysmenorrhea: a randomized, placebo controlled trial Journal of Endometriosis and Pelvic Pain Disorders, 2025
- TTP7.07 Levofloxacin based therapy vs Hybrid therapy in the eradication of Helicobacter pylori : A randomized controlled trial British Journal of Surgery, 2025
- Eye drops and eye gels of levofloxacin: comparison of ocular absorption characterizations and therapeutic effects in the treatment of bacterial keratitis in rabbits Drug Development and Industrial Pharmacy, 2020
- Pharmacokinetics, urinary excretion and milk penetration of levofloxacin in lactating goats Journal of Veterinary Pharmacology and Therapeutics, 2008
- Double-Blind Evaluation of the Safety and Pharmacokinetics of Multiple Oral Once-Daily 750-Milligram and 1-Gram Doses of Levofloxacin in Healthy Volunteers Antimicrobial Agents and Chemotherapy, 1998
- Pharmacokinetics and Pharmacodynamics of Intranasal Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Nose-to-Brain Delivery Pharmaceutics, 2022
- Amikacin Pharmacokinetics/Pharmacodynamics in a Novel Hollow-Fiber Mycobacterium abscessus Disease Model Antimicrobial Agents and Chemotherapy, 2015
- Integrating Pharmacokinetics and Pharmacodynamics in Operational Research to End Tuberculosis Clinical Infectious Diseases, 2019
- Levofloxacin pharmacodynamics against Stenotrophomonas maltophilia in a neutropenic murine thigh infection model: implications for susceptibility breakpoint revision Journal of Antimicrobial Chemotherapy, 2021
- The Hollow Fiber Infection Model for Antimicrobial Pharmacodynamics and Pharmacokinetics Advances in Pharmacoepidemiology & Drug Safety, 2012
- Synergistic Killing of Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula by Colistin Combined with Doripenem in an In Vitro Pharmacokinetic/Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2011
- Pharmacodynamics of fluoroquinolones Journal of Antimicrobial Chemotherapy, 1999
- Pharmacodynamic Modeling of Anti-Cancer Activity of Tetraiodothyroacetic Acid in a Perfused Cell Culture System PLoS Computational Biology, 2011
- Clinical Implications of Pharmacokinetics and Pharmacodynamics of Fluoroquinolones Clinical Infectious Diseases, 2005
- Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics British Journal of Pharmacology, 2011
- Pharmacodynamic profile of daptomycin against Enterococcus species and methicillin-resistant Staphylococcus aureus in a murine thigh infection model Journal of Antimicrobial Chemotherapy, 2003
- Pharmacodynamic Parameters of Pharmacokinetic/Pharmacodynamic (PK/PD) Integration Models Frontiers in Veterinary Science, 2022
- Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic–pharmacodynamic models with Monte Carlo simulation Journal of Antimicrobial Chemotherapy, 2008
- In vivo efficacy of humanized high dose meropenem and comparators against Pseudomonas aeruginosa isolates producing verona integron-encoded metallo-β-lactamase (VIM) Heliyon, 2016
- A therapeutic delivery system for chronic osteomyelitis via a multi-drug implant based on three-dimensional printing technology Journal of Biomaterials Applications, 2016
- Testing the mutant selection window hypothesis with Escherichia coli exposed to levofloxacin in a rabbit tissue cage infection model European Journal of Clinical Microbiology and Infectious Diseases, 2013
- Correlation between in vitro and in vivo activity of levofloxacin and moxifloxacin against pneumococcal strains with different susceptibilities to fluoroquinolones International Journal of Antimicrobial Agents, 2006
- In vitro pharmacodynamics of nemonoxacin and other antimicrobial agents against Mycoplasma pneumoniae Microbiology spectrum, 2023
- Levofloxacin activity at increasing doses in a murine model of fluoroquinolone-susceptible and -resistant tuberculosis Antimicrobial agents and chemotherapy, 2024
- Spermine-Conjugated Short Proline-Rich Lipopeptides as Broad-Spectrum Intracellular Targeting Antibacterial Agents Journal of medicinal chemistry, 2022
- D-cycloserine increases the effectiveness of vancomycin against vancomycin-highly resistant Staphylococcus aureus The Journal of antibiotics, 2017
- In vitro and in vivo efficacies of T-3811ME (BMS-284756) against Mycoplasma pneumoniae Antimicrobial agents and chemotherapy, 2001
- Antibacterial, tyrosinase, and DNA photocleavage studies of some triazolylnucleosides Nucleosides, nucleotides & nucleic acids, 2017
- Distribution of antimicrobial resistance among different serovars of Haemophilus parasuis isolates Veterinary microbiology, 2010
- Characterization and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from chicken and pork International journal of food microbiology, 2021
- Photohaptenic properties of fluoroquinolones Photochemistry and photobiology, 1996
- Pharmacokinetic and Pharmacodynamic Implications of P‐glycoprotein Modulation Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, 2001
- Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society Clinical Infectious Diseases, 2016
- Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults Clinical Infectious Diseases, 2007
- The Pharmacokinetic and Pharmacodynamic Profile of Tigecycline Clinical Infectious Diseases, 2005
- Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development Seminars in Respiratory and Critical Care Medicine, 2015
- Pharmacodynamics of Finafloxacin, Ciprofloxacin, and Levofloxacin in Serum and Urine against TEM- and SHV-Type Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae Isolates from Patients with Urinary Tract Infections Antimicrobial Agents and Chemotherapy, 2017
- Pharmacokinetic/pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine Journal of Veterinary Pharmacology and Therapeutics, 2004
- Pharmacokinetic and Pharmacodynamic Properties of Meropenem Clinical Infectious Diseases, 2008
- Urinary Pharmacokinetics and Theoretical Pharmacodynamics of Intravenous Levofloxacin in Intensive Care Unit Patients Treated with 500 mg b.i.d. for Ventilator-Associated Pneumonia Journal of Chemotherapy, 2003
- In vitro antibacterial activity and pharmacodynamics of new quinolones European Journal of Clinical Microbiology & Infectious Diseases, 2003
- Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniae International Journal of Antimicrobial Agents, 2005
- Evaluation of Immunocompetent Urinary Tract Infected Balb/C Mouse Model For the Study of Antibiotic Resistance Development Using Escherichia Coli CFT073 Infection Antibiotics (Basel, Switzerland), 2019
- Besifloxacin ophthalmic suspension: emerging evidence of its therapeutic value in bacterial conjunctivitis Ophthalmology and eye diseases, 2011
- Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations Pharmaceutics, 2020
- Clinical experimentation with aerosol antibiotics: current and future methods of administration Drug design, development and therapy, 2013
- Pulmonary infections complicating ARDS Intensive care medicine, 2020
- A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates Frontiers in immunology, 2022
- Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020
- Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques Pharmaceutics, 2020
- Characterizing the immune response to Mycobacterium tuberculosis: a comprehensive narrative review and implications in disease relapse Frontiers in immunology, 2024
- Simulated comparison of the pharmacodynamics of ciprofloxacin and levofloxacin against Pseudomonas aeruginosa using pharmacokinetic data from healthy volunteers and 2002 minimum inhibitory concentration data Clinical therapeutics, 2007
- A novel approach to pharmacodynamic assessment of antimicrobial agents: new insights to dosing regimen design PLoS computational biology, 2011
- Advances in antibiotic therapy in the critically ill Critical care (London, England), 2016
- Liposomal drug delivery to manage nontuberculous mycobacterial pulmonary disease and other chronic lung infections European respiratory review : an official journal of the European Respiratory Society, 2021
- Advancement in nanocarrier-mediated delivery of herbal bioactives: from bench to beside Natural products and bioprospecting, 2025
- Inhalable Nanoparticle-based Dry Powder Formulations for Respiratory Diseases: Challenges and Strategies for Translational Research AAPS PharmSciTech, 2023
- A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis Journal of clinical pharmacology, 2017
- Nanoparticle-mediated pulmonary drug delivery: state of the art towards efficient treatment of recalcitrant respiratory tract bacterial infections Drug delivery and translational research, 2021
- Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper# Intensive care medicine, 2020
- The Relationship Among Intestinal Bacteria, Vitamin K and Response of Vitamin K Antagonist: A Review of Evidence and Potential Mechanism Frontiers in medicine, 2022
- Advances in 3D-Printed Drug Delivery and Screening Platforms for Bone Disease Therapy Pharmaceutics, 2025
- Rising role of 3D-printing in delivery of therapeutics for infectious disease Journal of controlled release : official journal of the Controlled Release Society, 2024
- Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target Nature communications, 2024
- The challenges and strategies for navigating in vivo barriers to therapeutic bacterial delivery Theranostics, 2026
- Concise Clinical Review of Hematologic Toxicity of Linezolid in Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: Role of Mitochondria Tuberculosis and respiratory diseases, 2022
- Recent advances in electric-stimulus assisted microneedle patches for skin disease treatment Journal of nanobiotechnology, 2025
- Mathematical Models of Ocular Drug Delivery Investigative ophthalmology & visual science, 2024
- Discovery and development of a new oxazolidinone with reduced toxicity for the treatment of tuberculosis Nature medicine, 2026
- Antibiotic-Loaded Ultrahigh Molecular Weight Polyethylenes Macromolecular bioscience, 2024
- Phage therapy: breathing new tactics into lower respiratory tract infection treatments European respiratory review : an official journal of the European Respiratory Society, 2024
- Beyond Antibiotics: Repurposing Non-Antibiotic Drugs as Novel Antibacterial Agents to Combat Resistance International journal of molecular sciences, 2025
- Aerosolized delivery of ESKAPE pathogens for murine pneumonia models Scientific reports, 2024
- The Role of Sulopenem in the Treatment of Uncomplicated Urinary Tract Infections: A Systematic Review and Meta-Analysis Cureus, 2025
- Study on the Mechanism of Levofloxacin Combined with Imipenem Against Pseudomonas aeruginosa Applied biochemistry and biotechnology, 2024
- Evaluation of Mycobacterium tuberculosis cross-resistance to isoniazid, rifampicin and levofloxacin with their respective structural analogs The Journal of antibiotics, 2014
- In Vivo Emergence of Dual Resistance to Rifampin and Levofloxacin in Osteoarticular Cutibacterium avidum Microbiology spectrum, 2023
- Levofloxacin and trovafloxacin: the next generation of fluoroquinolones? American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997
- Looking for Stenotrophomonas maltophilia treatment: in vitro activity of ceftazidime/avibactam alone and in combination with aztreonam Journal of chemotherapy (Florence, Italy), 2023
- Carbapenem-Containing Combination Antibiotic Therapy against Carbapenem-Resistant Uropathogenic Enterobacteriaceae Antimicrobial agents and chemotherapy, 2019
- Multiclonal emergence of levofloxacin-resistant group B Streptococcus, Taiwan The Journal of antimicrobial chemotherapy, 2017
- Resistance reversal: Taiwan's Helicobacter pylori trends defy global norms World journal of gastroenterology, 2025
- Antimicrobial resistance of Helicobacter pylori in an eastern German region Helicobacter, 2021
- Targeted detection of Helicobacter pylori resistance to clarithromycin and levofloxacin using single-cell Raman spectroscopy Journal of medical microbiology, 2025
- Dynamic balance of pro‐ and anti‐inflammatory signals controls disease and limits pathology Immunological Reviews, 2018
- Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review—Part II Antibiotics, 2022
- Stenotrophomonas maltophilia in people with Cystic Fibrosis: a systematic review of prevalence, risk factors and management European Journal of Clinical Microbiology & Infectious Diseases, 2023
- Fosfomycin as Partner Drug for Systemic Infection Management. A Systematic Review of Its Synergistic Properties from In Vitro and In Vivo Studies Antibiotics, 2020
- Tuberculosis and pharmacological interactions: A narrative review Current Research in Pharmacology and Drug Discovery, 2020
- Model-Informed Precision Dosing of Antibiotics in Pediatric Patients: A Narrative Review Frontiers in Pediatrics, 2021
