Browse studies, page 1177
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- Fluoroquinolone Resistance in Escherichia coli Causing Community-Acquired Urinary Tract Infections: A Systematic Review Microorganisms, 2024
- The Effect of Levofloxacin Addition on the Outcome of Tuberculous Meningitis Patients: A Systematic Review and Meta-Analysis Magna Neurologica, 2024
- Development of an Antibiotic Resistance Breaker to Resensitize Drug-Resistant Staphylococcus aureus: In Silico and In Vitro Approach Frontiers in Cellular and Infection Microbiology, 2021
- Halogenated Antimicrobial Agents to Combat Drug-Resistant Pathogens Pharmacological Reviews, 2023
- Fluoroquinolone Analogs, SAR Analysis, and the Antimicrobial Evaluation of 7-Benzimidazol-1-yl-fluoroquinolone in In Vitro, In Silico, and In Vivo Models Molecules, 2023
- Comparison of the in vitro antibacterial activity of ofloxacin, levofloxacin, moxifloxacin, sitafloxacin, finafloxacin, and delafloxacin against Mycobacterium tuberculosis strains isolated in China Heliyon, 2023
- Escaping ESKAPE resistance: in vitro and in silico studies of multifunctional carbamimidoyl-tethered indoles against antibiotic-resistant bacteria Royal Society Open Science, 2023
- Fluoroquinolone Antimicrobial Agent Levofloxacin in Veterinary Medicine and its Pharmacokinetic-Pharmacodynamic Studies. Doctoral Thesis 2024
- Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling Journal of Medicinal Chemistry, 2012
- From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics Clinical Pharmacology & Therapeutics, 2021
- The Role of PK/PD Analysis in the Development and Evaluation of Antimicrobials Pharmaceutics, 2021
- Leveraging In Silico and Artificial Intelligence Models to Advance Drug Disposition and Response Predictions Across the Lifespan Clinical and Translational Science, 2025
- Detection of Drug-Drug Interactions by Modeling Interaction Profile Fingerprints PLoS ONE, 2013
- Results from the Survey of Antibiotic Resistance (SOAR) 2016–18 in Vietnam, Cambodia, Singapore and the Philippines: data based on CLSI, EUCAST (dose-specific) and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints Journal of Antimicrobial Chemotherapy, 2020
- Harnessing Hybrid Niosomes for Improved Oral Bioavailability of an Anticoagulant: Design, Optimization and In-Vivo Pharmacokinetics and Pharmacodynamics Evaluations AAPS PharmSciTech, 2026
- Experimental, DFT, molecular docking and in silico ADMET studies of cadmium-benzenetricarboxylates Eclética Química, 2022
- Comprehensive Pharmacokinetic Evaluation of High Melanin Binder Levofloxacin in Rabbits Shows Potential of Topical Eye Drops for Posterior Segment Treatment Investigative Ophthalmology & Visual Science, 2024
- Results from the Survey of Antibiotic Resistance (SOAR) 2015–17 in Turkey: data based on CLSI, EUCAST (dose-specific) and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints Journal of Antimicrobial Chemotherapy, 2020
- Population Pharmacokinetics and Bayesian Dose Adjustment to Advance TDM of Anti-TB Drugs Clinical Pharmacokinetics, 2021
- Amphotericin B- and Levofloxacin-Loaded Chitosan Films for Potential Use in Antimicrobial Wound Dressings: Analytical Method Development and Its Application Pharmaceutics, 2022
- Inclusion of a Phytomedicinal Flavonoid in Biocompatible Surface-Modified Chylomicron Mimic Nanovesicles with Improved Oral Bioavailability and Virucidal Activity: Molecular Modeling and Pharmacodynamic Studies Pharmaceutics, 2022
- Deposition of Inhaled Levofloxacin in Cystic Fibrosis Lungs Assessed by Functional Respiratory Imaging Pharmaceutics, 2021
- Development of Computational In Silico Model for Nano Lipid Carrier Formulation of Curcumin Molecules, 2023
- Capsaicin, a novel inhibitor of the NorA efflux pump, reduces the intracellular invasion of Staphylococcus aureus Journal of Antimicrobial Chemotherapy, 2012
- Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antibacterial Agents: A Review Clinical Pharmacokinetics, 2020
- Prediction of the pharmacokinetics and pharmacodynamics of topiroxostat in humans by integrating the physiologically based pharmacokinetic model with the drug-target residence time model Biomedicine & Pharmacotherapy, 2019
- Pharmacokinetic aspects of retinal drug delivery Progress in Retinal and Eye Research, 2016
- A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis European Respiratory Journal, 2017
- Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies Frontiers in Pharmacology, 2022
- Pharmacokinetics, Pharmacodynamics, and Dose Optimization of Cefiderocol during Continuous Renal Replacement Therapy Clinical Pharmacokinetics, 2021
- Oleocanthal as a Multifunctional Anti-Cancer Agent: Mechanistic Insights, Advanced Delivery Strategies, and Synergies for Precision Oncology International journal of molecular sciences, 2025
- In Silico Screening and Analysis of Broad-Spectrum Molecular Targets and Lead Compounds for Diarrhea Therapy Bioinformatics and biology insights, 2019
- Insights into the evolutionary trajectories of fluoroquinolone resistance in Streptococcus pneumoniae The Journal of antimicrobial chemotherapy, 2015
- Enhancing antibacterial efficacy through macrocyclic host complexation of fluoroquinolone antibiotics for overcoming resistance Scientific reports, 2024
- 8-octyl berberine combats Staphylococcus aureus by preventing peptidoglycan synthesis European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023
- New Potential Pharmacological Targets of Plant-Derived Hydroxyanthraquinones from Rubia spp Molecules (Basel, Switzerland), 2022
- Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening Journal of chemical information and modeling, 2014
- Pharmacokinetic considerations and efficacy of levofloxacin in an inhalational anthrax (postexposure) rhesus monkey model Antimicrobial agents and chemotherapy, 2006
- Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms Nature communications, 2021
- Discovery of psoralen as a quorum sensing inhibitor suppresses Pseudomonas aeruginosa virulence Applied microbiology and biotechnology, 2024
- Pharmacodynamic evaluation of i.v. antimicrobials against Pseudomonas aeruginosa samples collected from U.S. hospitals American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011
- Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa Chinese medicine, 2021
- Computational and Preclinical Prediction of the Antimicrobial Properties of an Agent Isolated from Monodora myristica: A Novel DNA Gyrase Inhibitor Molecules (Basel, Switzerland), 2023
- Efficacy of High Doses of Levofloxacin in Experimental Foreign-Body Infection by Methicillin-Susceptible Staphylococcus aureus Antimicrobial Agents and Chemotherapy, 2006
- In vitro pharmacodynamic activity of gatifloxacin, gemifloxacin, moxifloxacin and levofloxacin against Streptococcus pneumoniae containing specific mutations in DNA gyrase and topoisomerase IV. Diagnostic Microbiology and Infectious Disease, 2003
- Pharmacodynamics of gatifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model: impact of area under the curve/MIC ratios on eradication Antimicrobial Agents and Chemotherapy, 2002
- Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model International Journal of Antimicrobial Agents, 2005
- In Vitro Pharmacodynamic Activities of ABT-492, a Novel Quinolone, Compared to Those of Levofloxacin against Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis Antimicrobial Agents and Chemotherapy, 2003
- Linezolid, levofloxacin, and vancomycin against vancomycin-tolerant and fluoroquinolone-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, 2003
- In Vitro Pharmacodynamic Evaluation of the Mutant Selection Window Hypothesis Using Four Fluoroquinolones against Staphylococcus aureus Antimicrobial Agents and Chemotherapy, 2003
- Levofloxacin plus Metronidazole Administered Once Daily versus Moxifloxacin Monotherapy against a Mixed Infection of Escherichia coli and Bacteroides fragilis in an In Vitro Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2005
- Fluoroquinolone Resistance in Anaerobic Bacteria following Exposure to Levofloxacin, Trovafloxacin, and Sparfloxacin in an In Vitro Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2001
- Comparative pharmacodynamics of moxifloxacin and levofloxacin in an in vitro dynamic model: prediction of the equivalent AUC/MIC breakpoints and equiefficient doses Journal of Antimicrobial Chemotherapy, 2000
- Optimizing Antimicrobial Drug Dosing in Critically Ill Patients Microorganisms, 2021
- Development of an amoxicillin-radix scutellaria extract formulation and evaluation of its pharmacokinetics in pigs BMC veterinary research, 2023
- From genes to clinical management: A comprehensive review of long QT syndrome pathogenesis and treatment Heart rhythm O2, 2024
- On-Demand Drug Delivery Systems Using Nanofibers Nanomaterials (Basel, Switzerland), 2021
- Microneedles as a Promising Technology for Disease Monitoring and Drug Delivery: A Review ACS materials Au, 2025
- Infant Exposure to Antituberculosis Drugs via Breast Milk and Assessment of Potential Adverse Effects in Breastfed Infants: Critical Review of Data Pharmaceutics, 2023
- Update in tuberculosis treatment: a scoping review of current practices Breathe (Sheffield, England), 2025
- A Literature Review on the Impact of the Gut Microbiome on Cancer Treatment Efficacy, Disease Evolution and Toxicity: The Implications for Hematological Malignancies Journal of clinical medicine, 2025
- Deciphering the Intricate Interplay in the Framework of Antibiotic-Drug Interactions: A Narrative Review Antibiotics (Basel, Switzerland), 2024
- Drug-induced liver injury in inflammatory bowel disease: Challenges in diagnosis and monitoring World journal of hepatology, 2025
- Inflammation-Responsive Hydrogels in Perioperative Pain and Wound Management: Design Strategies and Emerging Potential Gels (Basel, Switzerland), 2025
- Advancement of Nanofibrous Mats and Common Useful Drug Delivery Applications Advances in pharmacological and pharmaceutical sciences, 2022
- Optimizing Pyrazinamide Use: A Low-Hanging Fruit in Improving Outcomes with Tuberculous Meningitis? Narrative Review Infectious diseases and therapy, 2025
- Dual-Drug Delivery Systems Using Hydrogel-Nanoparticle Composites: Recent Advances and Key Applications Gels (Basel, Switzerland), 2025
- Overcoming the drug resistance barrier: progress in fosfomycin combination therapy against multidrug-resistant pathogens Frontiers in microbiology, 2025
- Aerosolized delivery resulting in high polymyxin B concentration levels in epithelial lining fluid ensures efficacy in ventilator-associated pneumonia JAC-antimicrobial resistance, 2025
- Sitafloxacin pharmacokinetics/pharmacodynamics against multidrug-resistant bacteria in a dynamic urinary tract infection in vitro model The Journal of antimicrobial chemotherapy, 2022
- Pharmacokinetics of levofloxacin in Japanese quails (Coturnix japonica) following intravenous and oral administration British poultry science, 2012
- In vitro activity of Brucella melitensis isolates to various antimicrobials in Turkey Infectious diseases (London, England), 2015
- In Vitro Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin Antimicrobial agents and chemotherapy, 2017
- In vitro evaluation of antimicrobial resistance selection in Neisseria gonorrhoeae International journal of antimicrobial agents, 2021
- Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa Antimicrobial resistance and infection control, 2020
- Safety of levofloxacin as an antibiotic prophylaxis in the induction phase of children newly diagnosed with acute lymphoblastic leukemia: an interim analysis of a randomized, open-label trial in Brazil Brazilian Journal of Infectious Diseases, 2023
- Population Pharmacokinetics and Pharmacodynamics of Continuous versus Short-Term Infusion of Imipenem-Cilastatin in Critically Ill Patients in a Randomized, Controlled Trial Antimicrobial Agents and Chemotherapy, 2007
- Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: A Randomized Controlled Trial American Journal of Gastroenterology, 2022
- Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor Fenebrutinib (GDC‐0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial Arthritis & Rheumatology, 2021
- QT effects of bedaquiline, delamanid or both in patients with rifampicin-resistant-TB: a randomized controlled trial Lancet. Infectious Diseases (Print), 2021
- Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Luseogliflozin Dosing in Healthy Japanese Males: A Randomized, Single-Blind, Placebo-Controlled Trial Advances in Therapy, 2014
- Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial Journal of Investigative and Clinical Dentistry, 2015
- A phase 3 active-controlled trial of liposomal bupivacaine via sciatic nerve block in the popliteal fossa after bunionectomy Journal of clinical anesthesia, 2024
- An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study) American Journal of Respiratory and Critical Care Medicine, 2022
- FRI0084 safety, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of rozibafusp alfa in subjects with rheumatoid arthritis: interim analysis of a phase 1B randomized, placebo-controlled, multiple ascending dose clinical trial Annals of the Rheumatic Diseases, 2020
- A randomized controlled trial of levofloxacin, terazosin, and combination therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome International Urology and Nephrology, 2015
- A Phase 3 Active-Controlled Trial of Liposomal Bupivacaine via Adductor Canal Block for Total Knee Arthroplasty Journal of Arthroplasty, 2025
- Effect of preoperative prophylactic antibiotic use on postoperative infection after percutaneous nephrolithotomy in patients with negative urine culture: a single-center randomized controlled trial World journal of urology, 2023
- Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients with Acute Myocardial Infarction (IMPRESSION): study protocol for a randomized controlled trial Trials, 2015
- First-in-Human, Phase 1, Randomized, Double-Blind, Placebo-Controlled Study of TNX-1500, an Fc-Modified anti-CD154 Monoclonal Antibody, Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single-Ascending Doses in Healthy Adults Journal of Clinical Immunology, 2026
- AZD8630/AMG 104, an inhaled anti-thymic stromal lymphopoietin antibody fragment, for moderate-to-severe asthma: Phase 1 randomized controlled trial Journal of Allergy and Clinical Immunology, 2026
- Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women PLoS ONE, 2018
- Lack of improvement after short‐term topical antistaphylococcal endolysin SA.100 therapy in patients with mild‐to‐moderate atopic dermatitis: Results from a randomized, vehicle‐controlled trial British Journal of Clinical Pharmacology, 2026
- Design of CONQUEST, a novel, randomized, placebo-controlled, Phase 2b platform clinical trial to investigate new treatments for patients with early active systemic sclerosis with interstitial lung disease Journal of Scleroderma and Related Disorders, 2024
- Ten-Day Quadruple Therapy Comprising Proton Pump Inhibitor, Bismuth, Tetracycline, and Levofloxacin is More Effective than Standard Levofloxacin Triple Therapy in the Second-Line Treatment of Helicobacter pylori Infection: A Randomized Controlled Trial American Journal of Gastroenterology, 2017
- The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive—A randomized controlled trial British Journal of Clinical Pharmacology, 2020
- Epidural administration of ropivacaine and its effects on the pharmacodynamics of rocuronium: Randomized controlled trial. Interaction between ropivacaine and rocuronium Saudi Journal of Anaesthesia, 2020
- Safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of a novel anti-TSLP bispecific antibody (GR2002) in healthy Chinese adults: a randomized, placebo-controlled phase 1 trial European Journal of Pharmaceutical Sciences, 2026
- Pharmacokinetics and pharmacodynamics of intranasal remimazolam—a randomized controlled clinical trial European Journal of Clinical Pharmacology, 2020
- Efficacy and Safety of Combined Isoniazid-Rifampicin-Pyrazinamide-Levofloxacin Dry Powder Inhaler in Treatment of Pulmonary Tuberculosis: A Randomized Controlled Trial Pulmonary Pharmacology & Therapeutics, 2021