Browse studies, page 1299
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- Aerosolized delivery resulting in high polymyxin B concentration levels in epithelial lining fluid ensures efficacy in ventilator-associated pneumonia JAC-antimicrobial resistance, 2025
- Sitafloxacin pharmacokinetics/pharmacodynamics against multidrug-resistant bacteria in a dynamic urinary tract infection in vitro model The Journal of antimicrobial chemotherapy, 2022
- Pharmacokinetics of levofloxacin in Japanese quails (Coturnix japonica) following intravenous and oral administration British poultry science, 2012
- In vitro activity of Brucella melitensis isolates to various antimicrobials in Turkey Infectious diseases (London, England), 2015
- In Vitro Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin Antimicrobial agents and chemotherapy, 2017
- In vitro evaluation of antimicrobial resistance selection in Neisseria gonorrhoeae International journal of antimicrobial agents, 2021
- Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa Antimicrobial resistance and infection control, 2020
- Safety of levofloxacin as an antibiotic prophylaxis in the induction phase of children newly diagnosed with acute lymphoblastic leukemia: an interim analysis of a randomized, open-label trial in Brazil Brazilian Journal of Infectious Diseases, 2023
- Population Pharmacokinetics and Pharmacodynamics of Continuous versus Short-Term Infusion of Imipenem-Cilastatin in Critically Ill Patients in a Randomized, Controlled Trial Antimicrobial Agents and Chemotherapy, 2007
- Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: A Randomized Controlled Trial American Journal of Gastroenterology, 2022
- Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor Fenebrutinib (GDC‐0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial Arthritis & Rheumatology, 2021
- QT effects of bedaquiline, delamanid or both in patients with rifampicin-resistant-TB: a randomized controlled trial Lancet. Infectious Diseases (Print), 2021
- Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Luseogliflozin Dosing in Healthy Japanese Males: A Randomized, Single-Blind, Placebo-Controlled Trial Advances in Therapy, 2014
- Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial Journal of Investigative and Clinical Dentistry, 2015
- A phase 3 active-controlled trial of liposomal bupivacaine via sciatic nerve block in the popliteal fossa after bunionectomy Journal of clinical anesthesia, 2024
- An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study) American Journal of Respiratory and Critical Care Medicine, 2022
- FRI0084 safety, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of rozibafusp alfa in subjects with rheumatoid arthritis: interim analysis of a phase 1B randomized, placebo-controlled, multiple ascending dose clinical trial Annals of the Rheumatic Diseases, 2020
- A randomized controlled trial of levofloxacin, terazosin, and combination therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome International Urology and Nephrology, 2015
- A Phase 3 Active-Controlled Trial of Liposomal Bupivacaine via Adductor Canal Block for Total Knee Arthroplasty Journal of Arthroplasty, 2025
- Effect of preoperative prophylactic antibiotic use on postoperative infection after percutaneous nephrolithotomy in patients with negative urine culture: a single-center randomized controlled trial World journal of urology, 2023
- Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients with Acute Myocardial Infarction (IMPRESSION): study protocol for a randomized controlled trial Trials, 2015
- First-in-Human, Phase 1, Randomized, Double-Blind, Placebo-Controlled Study of TNX-1500, an Fc-Modified anti-CD154 Monoclonal Antibody, Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single-Ascending Doses in Healthy Adults Journal of Clinical Immunology, 2026
- AZD8630/AMG 104, an inhaled anti-thymic stromal lymphopoietin antibody fragment, for moderate-to-severe asthma: Phase 1 randomized controlled trial Journal of Allergy and Clinical Immunology, 2026
- Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women PLoS ONE, 2018
- Lack of improvement after short‐term topical antistaphylococcal endolysin SA.100 therapy in patients with mild‐to‐moderate atopic dermatitis: Results from a randomized, vehicle‐controlled trial British Journal of Clinical Pharmacology, 2026
- Design of CONQUEST, a novel, randomized, placebo-controlled, Phase 2b platform clinical trial to investigate new treatments for patients with early active systemic sclerosis with interstitial lung disease Journal of Scleroderma and Related Disorders, 2024
- Ten-Day Quadruple Therapy Comprising Proton Pump Inhibitor, Bismuth, Tetracycline, and Levofloxacin is More Effective than Standard Levofloxacin Triple Therapy in the Second-Line Treatment of Helicobacter pylori Infection: A Randomized Controlled Trial American Journal of Gastroenterology, 2017
- The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive—A randomized controlled trial British Journal of Clinical Pharmacology, 2020
- Epidural administration of ropivacaine and its effects on the pharmacodynamics of rocuronium: Randomized controlled trial. Interaction between ropivacaine and rocuronium Saudi Journal of Anaesthesia, 2020
- Safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of a novel anti-TSLP bispecific antibody (GR2002) in healthy Chinese adults: a randomized, placebo-controlled phase 1 trial European Journal of Pharmaceutical Sciences, 2026
- Pharmacokinetics and pharmacodynamics of intranasal remimazolam—a randomized controlled clinical trial European Journal of Clinical Pharmacology, 2020
- Efficacy and Safety of Combined Isoniazid-Rifampicin-Pyrazinamide-Levofloxacin Dry Powder Inhaler in Treatment of Pulmonary Tuberculosis: A Randomized Controlled Trial Pulmonary Pharmacology & Therapeutics, 2021
- Safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 685509, a soluble guanylyl cyclase activator, in healthy volunteers: Results from two randomized controlled trials Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Pharmacokinetics, pharmacodynamics, safety and tolerability of FTP-198, a novel, selective autotaxin inhibitor, in healthy subjects: a phase I randomized placebo-controlled trial European Journal of Pharmaceutical Sciences, 2023
- Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in Patients with Parkinson’s Disease and a GBA Mutation: Results from Part 1 of the Randomized, Double-Blinded, Placebo-Controlled MOVES-PD Trial Journal of Parkinson's Disease, 2021
- The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and dose-escalation phase I trial Naunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT‐4202), an Allosteric Activator of Pyruvate Kinase‐R, in Healthy Adults: A Randomized, Placebo‐Controlled, Double‐Blind, First‐in‐Human Phase 1 Trial Clinical pharmacology in drug development, 2022
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Positive Modulator of HGF/MET, Fosgonimeton, in Healthy Volunteers and Subjects with Alzheimer’s Disease: Randomized, Placebo-Controlled, Double-Blind, Phase I Clinical Trial Journal of Alzheimer's Disease, 2022
- Levofloxacin+Tetracycline Quadruple Regimen for Eradication of Helicobacter pylori: A Multicenter Multinational Randomized Controlled Trial Middle East Journal of Digestive Diseases, 2023
- Riluzole in Spinal Cord Injury Study (RISCIS)–Pharmacokinetic (PK) Sub-Study: An Analysis of Pharmacokinetics, Pharmacodynamics, and Impact on Axonal Degradation of Riluzole in Patients With Traumatic Cervical Spinal Cord Injury Enrolled in the RISCIS Phase III Randomized Controlled Trial Journal of Neurotrauma, 2023
- OP20 Results from the STENOVA trial: A Phase 2a, randomized, placebo-controlled, double-blind study to assess the safety, pharmacokinetics (PK), and pharmacodynamics of ontunisertib (AGMB-129) in patients with Fibrostenotic Crohn’s Disease (FSCD) Journal of Crohn's & Colitis, 2026
- Pharmacokinetics/pharmacodynamics of benralizumab in chronic rhinosinusitis with nasal polyps: Phase III, randomized, placebo‐controlled OSTRO trial British Journal of Clinical Pharmacology, 2024
- Safety, pharmacokinetics, and preliminary pharmacodynamics of 1% and 3% diclofenac vaginal hydrogel for the treatment of primary dysmenorrhea: a randomized, placebo controlled trial Journal of Endometriosis and Pelvic Pain Disorders, 2025
- TTP7.07 Levofloxacin based therapy vs Hybrid therapy in the eradication of Helicobacter pylori : A randomized controlled trial British Journal of Surgery, 2025
- Eye drops and eye gels of levofloxacin: comparison of ocular absorption characterizations and therapeutic effects in the treatment of bacterial keratitis in rabbits Drug Development and Industrial Pharmacy, 2020
- Pharmacokinetics, urinary excretion and milk penetration of levofloxacin in lactating goats Journal of Veterinary Pharmacology and Therapeutics, 2008
- Double-Blind Evaluation of the Safety and Pharmacokinetics of Multiple Oral Once-Daily 750-Milligram and 1-Gram Doses of Levofloxacin in Healthy Volunteers Antimicrobial Agents and Chemotherapy, 1998
- Pharmacokinetics and Pharmacodynamics of Intranasal Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Nose-to-Brain Delivery Pharmaceutics, 2022
- Amikacin Pharmacokinetics/Pharmacodynamics in a Novel Hollow-Fiber Mycobacterium abscessus Disease Model Antimicrobial Agents and Chemotherapy, 2015
- Integrating Pharmacokinetics and Pharmacodynamics in Operational Research to End Tuberculosis Clinical Infectious Diseases, 2019
- Levofloxacin pharmacodynamics against Stenotrophomonas maltophilia in a neutropenic murine thigh infection model: implications for susceptibility breakpoint revision Journal of Antimicrobial Chemotherapy, 2021
- The Hollow Fiber Infection Model for Antimicrobial Pharmacodynamics and Pharmacokinetics Advances in Pharmacoepidemiology & Drug Safety, 2012
- Synergistic Killing of Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula by Colistin Combined with Doripenem in an In Vitro Pharmacokinetic/Pharmacodynamic Model Antimicrobial Agents and Chemotherapy, 2011
- Pharmacodynamics of fluoroquinolones Journal of Antimicrobial Chemotherapy, 1999
- Pharmacodynamic Modeling of Anti-Cancer Activity of Tetraiodothyroacetic Acid in a Perfused Cell Culture System PLoS Computational Biology, 2011
- Clinical Implications of Pharmacokinetics and Pharmacodynamics of Fluoroquinolones Clinical Infectious Diseases, 2005
- Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics British Journal of Pharmacology, 2011
- Pharmacodynamic profile of daptomycin against Enterococcus species and methicillin-resistant Staphylococcus aureus in a murine thigh infection model Journal of Antimicrobial Chemotherapy, 2003
- Pharmacodynamic Parameters of Pharmacokinetic/Pharmacodynamic (PK/PD) Integration Models Frontiers in Veterinary Science, 2022
- Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic–pharmacodynamic models with Monte Carlo simulation Journal of Antimicrobial Chemotherapy, 2008
- In vivo efficacy of humanized high dose meropenem and comparators against Pseudomonas aeruginosa isolates producing verona integron-encoded metallo-β-lactamase (VIM) Heliyon, 2016
- A therapeutic delivery system for chronic osteomyelitis via a multi-drug implant based on three-dimensional printing technology Journal of Biomaterials Applications, 2016
- Testing the mutant selection window hypothesis with Escherichia coli exposed to levofloxacin in a rabbit tissue cage infection model European Journal of Clinical Microbiology and Infectious Diseases, 2013
- Correlation between in vitro and in vivo activity of levofloxacin and moxifloxacin against pneumococcal strains with different susceptibilities to fluoroquinolones International Journal of Antimicrobial Agents, 2006
- In vitro pharmacodynamics of nemonoxacin and other antimicrobial agents against Mycoplasma pneumoniae Microbiology spectrum, 2023
- Levofloxacin activity at increasing doses in a murine model of fluoroquinolone-susceptible and -resistant tuberculosis Antimicrobial agents and chemotherapy, 2024
- Spermine-Conjugated Short Proline-Rich Lipopeptides as Broad-Spectrum Intracellular Targeting Antibacterial Agents Journal of medicinal chemistry, 2022
- D-cycloserine increases the effectiveness of vancomycin against vancomycin-highly resistant Staphylococcus aureus The Journal of antibiotics, 2017
- In vitro and in vivo efficacies of T-3811ME (BMS-284756) against Mycoplasma pneumoniae Antimicrobial agents and chemotherapy, 2001
- Antibacterial, tyrosinase, and DNA photocleavage studies of some triazolylnucleosides Nucleosides, nucleotides & nucleic acids, 2017
- Distribution of antimicrobial resistance among different serovars of Haemophilus parasuis isolates Veterinary microbiology, 2010
- Characterization and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from chicken and pork International journal of food microbiology, 2021
- Photohaptenic properties of fluoroquinolones Photochemistry and photobiology, 1996
- Pharmacokinetic and Pharmacodynamic Implications of P‐glycoprotein Modulation Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, 2001
- Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society Clinical Infectious Diseases, 2016
- Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults Clinical Infectious Diseases, 2007
- The Pharmacokinetic and Pharmacodynamic Profile of Tigecycline Clinical Infectious Diseases, 2005
- Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development Seminars in Respiratory and Critical Care Medicine, 2015
- Pharmacodynamics of Finafloxacin, Ciprofloxacin, and Levofloxacin in Serum and Urine against TEM- and SHV-Type Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae Isolates from Patients with Urinary Tract Infections Antimicrobial Agents and Chemotherapy, 2017
- Pharmacokinetic/pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine Journal of Veterinary Pharmacology and Therapeutics, 2004
- Pharmacokinetic and Pharmacodynamic Properties of Meropenem Clinical Infectious Diseases, 2008
- Urinary Pharmacokinetics and Theoretical Pharmacodynamics of Intravenous Levofloxacin in Intensive Care Unit Patients Treated with 500 mg b.i.d. for Ventilator-Associated Pneumonia Journal of Chemotherapy, 2003
- In vitro antibacterial activity and pharmacodynamics of new quinolones European Journal of Clinical Microbiology & Infectious Diseases, 2003
- Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniae International Journal of Antimicrobial Agents, 2005
- Evaluation of Immunocompetent Urinary Tract Infected Balb/C Mouse Model For the Study of Antibiotic Resistance Development Using Escherichia Coli CFT073 Infection Antibiotics (Basel, Switzerland), 2019
- Besifloxacin ophthalmic suspension: emerging evidence of its therapeutic value in bacterial conjunctivitis Ophthalmology and eye diseases, 2011
- Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations Pharmaceutics, 2020
- Clinical experimentation with aerosol antibiotics: current and future methods of administration Drug design, development and therapy, 2013
- Pulmonary infections complicating ARDS Intensive care medicine, 2020
- A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates Frontiers in immunology, 2022
- Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020
- Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques Pharmaceutics, 2020
- Characterizing the immune response to Mycobacterium tuberculosis: a comprehensive narrative review and implications in disease relapse Frontiers in immunology, 2024
- Simulated comparison of the pharmacodynamics of ciprofloxacin and levofloxacin against Pseudomonas aeruginosa using pharmacokinetic data from healthy volunteers and 2002 minimum inhibitory concentration data Clinical therapeutics, 2007
- A novel approach to pharmacodynamic assessment of antimicrobial agents: new insights to dosing regimen design PLoS computational biology, 2011
- Advances in antibiotic therapy in the critically ill Critical care (London, England), 2016
- Liposomal drug delivery to manage nontuberculous mycobacterial pulmonary disease and other chronic lung infections European respiratory review : an official journal of the European Respiratory Society, 2021
- Advancement in nanocarrier-mediated delivery of herbal bioactives: from bench to beside Natural products and bioprospecting, 2025
- Inhalable Nanoparticle-based Dry Powder Formulations for Respiratory Diseases: Challenges and Strategies for Translational Research AAPS PharmSciTech, 2023
- A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis Journal of clinical pharmacology, 2017
