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Efficacy of laser therapy for exercise-induced fatigue: A meta-analysis

Wang D, Wang X

Medicine, 2019

394 participants

Abstract

BACKGROUND: Laser therapy is widely used for exercise-induced fatigue, while the effect among different studies remains controversial. The present study was to summary available randomized controlled trials (RCTs) to evaluate the effect of laser therapy in subjects with exercise-induced fatigue.

METHODS: PubMed, Embase, and Cochrane Library were searched to identify the potential RCTs from inception to October 2017. The weighted mean difference (WMD) with 95% confidence intervals (CIs) was calculated using a random-effects model.

RESULTS: Twenty RCTs involving a total of 394 individuals were included in final analysis. No significant differences were observed between the laser therapy and control for the outcomes of lactate (WMD: -0.19; 95%CI: -0.52 to 0.13; P = .244), repetitions (WMD: 4.44; 95%CI: -1.43 to 10.32; P = .138), work load (WMD: 3.38; 95%CI: -1.15 to 7.91; P = .144), time taken to perform the exercise tests (WMD: 4.42; 95%CI: -2.33 to 11.17; P = .199), creatine kinase (WMD: -41.80; 95%CI: -168.78 to 85.17; P = .519), maximum voluntary contraction (WMD: 23.83; 95%CI: -7.41 to 55.07; P = .135), mean peak forces (WMD: 2.87; 95%CI: -1.01 to 6.76; P = = .147), and visual analog scale (VAS) (WMD: -1.91; 95%CI: -42.89 to 39.08; P = = .927). The results of sensitivity analysis suggested that laser therapy might play an important role on the levels of lactate (WMD: -0.30; 95%CI: -0.59 to -0.01; P = = .040), maximum voluntary contraction (WMD: 33.54; 95%CI: 1.95 to 65.12;…

How strong is the evidence?

Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 394 participants or records.

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