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Acute and Chronic Effects of Accentuated Eccentric Loading vs. Constant-Load Resistance Training: A Systematic Review and Meta-analysis

Zhang X, Weakley J, Li H, Marcos-Frutos D, García-Ramos A

Sports medicine (Auckland, N.Z.), 2026

773 participants

Abstract

Background: Accentuated eccentric loading (AEL) is a resistance training (RT) method applying greater eccentric- than concentric-phase load to intensify the training stimulus; however, despite its common use, a comprehensive and quantitative review remains lacking.

Objective: The aim was to compare acute responses and chronic adaptations between AEL and constant-load RT, and examine whether effects vary by AEL protocol (submaximal, maximal, supramaximal).

Methods: PubMed, Web of Science, Embase, and EBSCO were searched from inception through July 3, 2024; eligible English-language studies were included. Pooled and subgroup meta-analyses were performed using random-effects models.

Results: Forty-nine studies involving 773 participants were included. Although considerable variance exists in certain outcomes, our estimated effects suggest that, compared to constant-load RT, AEL results in (1) similar acute responses in loads lifted during the concentric phase (standardized mean difference [SMD] = - 0.16; p = 0.48), mechanical performance at submaximal loads during the concentric phase (SMD = - 0.07; p = 0.37), countermovement jump height both immediately (SMD = - 0.06; p = 0.86) and delayed (SMD = - 0.23; p = 0.44) post-intervention, maximal voluntary isometric force immediately post-intervention (SMD = 0.03; p = 0.89), blood lactate concentration during the intervention (SMD = - 0.06; p = 0.78), testosterone concentration immediately post-intervention (SMD = 0.68; p = 0.15),…

How strong is the evidence?

Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 773 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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