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Effects of Nutritional Supplements on Explosive Lower Limb Performance in Volleyball Players: A Systematic Review and Network Meta-Analysis

Du H, Liu S, Li M, Zhao K, Jiang W, You T, Wang Z, Zou D et al.

Nutrients, 2025

838 participants · 4 citations

Abstract

Background: Explosive lower limb power, a critical determinant of success in volleyball, is a prime candidate for focused research. Consequently, nutritional supplements are commonly employed to gain an ergogenic edge. Despite this widespread practice, a comprehensive and evidence-based ranking of supplements for improving this key attribute is lacking, leaving athletes and practitioners without targeted evidence to guide decisions. Methods: PubMed, Web of Science, CENTRAL, and Embase were searched from inception to 1 August 2025. We included RCTs in volleyball athletes (≥14 years) with ≥1-week interventions and relevant explosive lower limb performance outcomes. A Bayesian NMA estimated effects with 95% credible intervals (CrIs) and SUCRA; certainty was appraised with CINeMA. Results: A total of 35 RCTs (n = 838 volleyball athletes) examining 13 different supplements were included. The results indicated that β-alanine was associated with the greatest improvement in vertical jump (MD 4.6; 95% CrI 1.2-7.8), followed by creatine (MD 3.7; 0.57-6.9) and caffeine (MD 2.1; 0.06-4.1). It also appeared to be the most promising method for substantially increasing lower limb peak power (SMD 1.1; 0.21-2.0). No statistically significant improvement was found in lower limb mean power, and no serious adverse events were reported. Conclusions: Among volleyball athletes, β-alanine appeared most promising effective supplement for enhancing key components of explosive lower limb performance,…

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Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 838 participants or records.

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