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Creatine Supplementation in Patients With Cancer: A Systematic Review and Meta‐Analysis

Luciana Moura Leite, H. Brito, R. L. Nohmi, F. Marques, Pedro Paulo Dal Bello, D. V. Araujo

JCSM Communications, 2026

Abstract

Creatine supplementation (CrSUPP) has demonstrated benefits in improving body composition, muscle strength and physical function in healthy older adults. However, preclinical studies have raised concerns about the potential for CrSUPP to negatively impact cancer outcomes. This systematic review and meta‐analysis aimed to evaluate the efficacy and safety of CrSUPP in patients with cancer.

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