Evidence Hub

Levocetirizine for the complex treatment of allergic dermatitis

L. Kruglova, A. Bakulev

Russian Medical Inquiry, 2022

Abstract

Allergic dermatitis is one of the most common skin diseases. Pathogenically, allergic dermatitis is a delayed hypersensitivity reaction. Allergic dermatitis is provoked by various agents that penetrate the skin. More than 3,500 potential contact allergens were described. The immune response in allergic dermatitis is conventionally characterized by two phases, afferent and efferent. Treatment for allergic dermatitis includes topical and systemic therapies (antihistamines) and physiotherapy. The authors address their experience with the management of patients with allergic dermatitis. Twenty-eight patients were enrolled. The predominant clinical manifestations were erythematous lesions, infiltration, and vesicles associated with itching. All patients received levocetirizine 5 mg daily and topical steroids (methylprednisolone acetate propionate) for 10–15 days. After 2 weeks, this treatment resulted in complete symptom relief. Complex treatment for allergic dermatitis (levocetirizine 5 mg daily and topical steroids) is effective against all clinical symptoms, including itching. KEYWORDS: allergic dermatitis, treatment, antihistamines, levocetirizine, visual analogue scale, Dermatology Life Quality Index. FOR CITATION: Kruglova L.S., Bakulev A.L. Levocetirizine for the complex treatment of allergic dermatitis. Russian Medical Inquiry. 2022;6(2):105–109 (in Russ.). DOI: 10.32364/2587-6821-2022-6-2-105-109.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free