Intramuscular Compound Betamethasone for the Emergent Management of Lingual Angioedema
Abstract
A 38-year-old male developed acute tongue swelling with slurred speech 2 hours after taking amoxicillin. On the basis of the patient's history, physical and oral examination, and laboratory findings, the diagnosis was confirmed as histamine-mediated lingual angioedema. Treatment included immediate discontinuation of amoxicillin, intramuscular injection of compound betamethasone, and oral levocetirizine. Tongue swelling resolved completely within 1 hour, with no recurrence at 3-day and 1-week follow-ups. The occurrence of histamine-mediated angioedema solely in the tongue is highly uncommon. Such swelling may progress to airway obstruction and asphyxia, becoming a life-threatening emergency, which requires prompt evaluation and management. Compound betamethasone offers rapid onset and sustained efficacy through a convenient intramuscular route, presenting distinct advantages for angioedema management. When combined with antihistamines, it may be a valuable option for acute emergencies encountered in oral practice.
Read the paper
Related studies
- Artificial Intelligence in Medicine: Cross-Sectional Study Among Medical Students on Application, Education, and Ethical Aspects
- Information quality of videos related to esophageal cancer on tiktok, kwai, and bilibili: a cross-sectional study
- The quality and reliability of short videos about hypertension on TikTok: a cross-sectional study
- Quality and reliability evaluation of pancreatic cancer-related video content on social short video platforms: a cross-sectional study
- Quality and reliability of pediatric pneumonia related short videos on mainstream platforms: cross-sectional study
- Association between metabolic score for insulin resistance (METS-IR) and hypertension: a cross-sectional study based on NHANES 2007–2018
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.