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Evaluation of prescription pattern and drug adherence in patients with psoriasis: A cross-sectional study

Sarvendra Vikram Singh, Sujata Singh, Shalini Chandra, Iram Shaifali, Anju Saxena, Manikanta Gupta Bayya, P. Agarwal, Nasra Banu

Asian Journal of Medical Sciences, 2026

Abstract

Background: Psoriasis is a chronic inflammatory skin disorder associated with significant morbidity and impaired quality of life. Understanding prescribing patterns and treatment adherence is essential for optimizing patient outcomes.

Aims and Objectives: The aims and objectives of the study are to evaluate the clinical profile, prescribing patterns, and factors affecting drug adherence among psoriasis patients in a tertiary care hospital.

Materials and Methods: A cross-sectional observational study was conducted among diagnosed psoriasis patients. Demographic details, clinical characteristics, treatment patterns, and drug adherence were assessed using the 8-item Morisky Medication Adherence Scale, a validated tool with defined scoring categories that were recorded and analyzed statistically.

Results: The majority of patients (44%) were in the 30–45-year age group, with a significant male predominance (70%, P=0.005). Most participants were from rural areas (68%) and belonged to the Hindu religion (82%). Plaque psoriasis was the most common clinical type. Topical therapy was widely used, with Aloe vera+Vitamin E lotion (84%) and clobetasol+salicylic acid (82%) being the most frequently prescribed agents. Among systemic therapies, levocetirizine (96%) and vitamin A (86%) were commonly used, while methotrexate was prescribed in 40% of patients. Polypharmacy was observed, with an average of 5.6 drugs per prescription. Generic prescribing was low, and antibiotic use was minimal.…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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