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Abrocitinib: A Comprehensive Review of its Efficacy and Safety in Dermatology

Dogra S, Shah S, Gupta M, Sharma A, Chhabra S

Indian dermatology online journal, 2024

6 citations

Abstract

Abrocitinib is a novel oral small molecule which acts as a selective JAK-1 inhibitor. Currently approved for use in moderate-to-severe cases of atopic dermatitis, this drug is gaining a rapid impetus for its use across various inflammatory dermatoses for its selective downstream action on cytokines of the JAK-1 pathway. Its efficacy and safety in atopic dermatitis has been established in phase 3 clinical trials. The future implication of this drug will depend largely on feasibility and practical use in Indian scenario.

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