Clinician’s perspectives on the use of levocetirizine alone or in combination therapy in allergic rhinitis
Abstract
Objective: To gather expert perspectives on the use of levocetirizine-montelukast combination in managing allergic rhinitis (AR) within the Indian context. Methods: A cross-sectional study was conducted among clinical experts using a 24-item questionnaire to collect their opinion on the use of levocetirizine, both as monotherapy and in combination with montelukast, in the routine management of AR. The survey explored various aspects such as clinical observations, clinician preferences, and experiences with levocetirizine alone and in combination with montelukast. Data were analyzed using descriptive statistics. Results: The survey included 551 experts. A substantial proportion (72%) indicated that patient visits for AR symptoms are most frequent during the winter season. Asthma emerged as the most commonly associated comorbidity, as reported by 86% of physicians. The majority (90%) identified levocetirizine as their preferred antihistamine in clinical practice. Around 78% of respondents consistently favored combining montelukast with antihistamines for treating AR, and 93% specifically preferred the levocetirizine-montelukast combination. Sedation was reported as the most frequent adverse effect associated with levocetirizine by 84% of respondents. Furthermore, 84% of practitioners indicated that their first-line approach for managing AR involves a combination of an antihistamine and montelukast. Additionally, 58% believed that incorporating montelukast with an antihistamine…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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