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Efficacy of Communication Bridge‐2 for primary progressive aphasia: A randomized controlled trial of communication intervention

E. Rogalski, Matthew Bona, Marissa Esparza, Ollie Fegter, Rhiana Schafer, A. Mooney, Melanie Fried-Oken, Alfred Rademaker et al.

Alzheimer's & Dementia, 2025

13 citations

Abstract

Primary progressive aphasia (PPA), a language‐based neurodegenerative dementia, negatively impacts communication and quality of life. Previous non‐pharmacologic interventions show promise but lack efficacy trials. Here, outcomes are provided from Communication Bridge‐2 (CB2), a speech‐language randomized controlled trial (RCT) for PPA.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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