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Efficacy of Telemedical Interventional Management in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention: Randomized Controlled Trial

Xiao-Fan Yu, Jiao-Yu Cao, Jie Xu, Qi-Zhi Xu, Hong-Wei Chen, D. Yu, An-Ping Ou, Yue Hu et al.

Journal of Medical Internet Research, 2025

2,086 participants · 9 citations

Abstract

Abstract Background Coronary heart disease (CHD) continues to be a leading cause of global morbidity and mortality, with patients undergoing percutaneous coronary intervention (PCI) facing a significant risk of recurrent cardiovascular events. While secondary prevention strategies, such as medication adherence and lifestyle modifications, are essential, implementation gaps remain due to limited health care access and inadequate patient engagement. Telemedical interventions offer a promising solution to these challenges by facilitating remote monitoring and providing individualized patient management strategies. Objective This randomized controlled trial aimed to evaluate the efficacy of a comprehensive web-based telemedical interventional management system in reducing major adverse cardiac and cerebrovascular events (MACCE) and enhancing secondary prevention outcomes among patients with CHD following PCI, compared to usual care alone. Methods We conducted a single-center, open-label, randomized controlled trial at a tertiary hospital in China. A total of 2086 patients with post-PCI CHD were randomly assigned in a 1:1 ratio to receive either telemedical management combined with usual care (intervention group; n=1040) or usual care alone (control group; n=1046). The control group received follow-up phone calls from health care providers at 1, 3, 6, and 12 months after discharge. In contrast, the remote patient management group benefited from multicomponent interventions…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 2,086 participants or records.

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