Dietary patterns and risk of cervical cancer: A case-control study
Abstract
Objective: Cervical cancer (CC) is the second most frequent malignancy. Infections with the human papillomavirus have a crucial role in the Pathology of CC. The association of nutrient and dietary pattern with CC have been reported in few studies. This study was conducted to evaluate the relationship between dietary patterns and CC situations in the Iranian population. Method: This is a case-control study in which totally 260 controls and 132 patients aged 30-79 were included as control, and case groups. Dietary data were evaluated by 147-items semi-quantitative food frequency questionnaire. Multivariate logistic regression was used to estimate the relationship between dietary patterns and risk of cervical cancer. Results: Statistical analysis investigated two dietary patterns (healthy and unhealthy). Two dietary patterns covered 17.76% of total variance of dietary intake. Higher adherence of the unhealthy dietary pattern was associated with increased risk of CC (OR = 2.23, 95% CI = 1.77-4.24); however, there was no association between healthy dietary pattern and CC (OR = 1.91, 95% CI = 0.90-3.20). Conclusion: Our results indicate that unhealthy dietary pattern is significantly associated with CC.
How strong is the evidence?
Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 132 participants or records.
Read the paper
Related studies
- Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- A meta‐analysis of anal cancer incidence by risk group: Toward a unified anal cancer risk scale
- Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials
- Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis
- Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.