Atypical Presentation of Two Chikungunya Cases: A Case Series during 2025 Outbreak
Abstract
Bangladesh is experiencing a sharp rise in viral infections, particularly during the current monsoon season. Dengue, chikungunya, and COVID-19 are now posing a triple threat to public health. As their symptoms are overlapping, a strong diagnostic support is pivotal in severe cases.Here, we describe two older male chikungunya virus patients who, in addition to their typical symptoms, have significant organ involvement. Pneumonia caused by chikungunya affecting the lungs occurred in the first patient. The second case had similar lung involvement with encephalitis. Both had diabetes and hypertension, two co-morbidities that increase the chance of developing serious illness. The second case was also a known case of chronic kidney disease (CKD), old cerebrovascular disease (CVD) and ischaemic heart disease (IHD). He was transferred to the critical care unit and eventually passed away. These cases demonstrate how crucial it is that Chikungunya PCR tests be made available across the country at a reasonable cost in order to prevent needless treatment and investigations as well as early case diagnosis.
Bangladesh J Medicine 2025; 36(3): 147-154
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- A meta‐analysis of anal cancer incidence by risk group: Toward a unified anal cancer risk scale
- Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials
- Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis
- Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.