Five-year reoperation rates after Schlemm's canal-based glaucoma surgery versus trabeculectomy
Abstract
OBJECTIVE
To compare 5-year reoperation rates between Schlemm's canal (SC)-based glaucoma surgery and trabeculectomy (Trab), and to identify risk factors for reoperations.
DESIGN
Retrospective case series.
METHODS
This retrospective study included patients who underwent glaucoma surgery between January 2017 and December 2021. Propensity score matching was used to identify comparable participants among groups. SC-based glaucoma surgery included gonioscopy-assisted transluminal trabeculotomy, microcatheter-assisted trabeculotomy, ab-interno canaloplasty, canaloplasty, and trabectome. The primary outcome was unanticipated reoperations after the original procedure. Kaplan-Meier survival analysis compared reoperation rates between groups. Univariate and multivariate Cox regression analyses identified risk factors for reoperation.
RESULTS
The final analysis included 112 eyes (106 patients) in the SC-based glaucoma surgery group and 147 eyes (137 patients) in the Trab group. The 5-year cumulative reoperation rate was significantly higher in the Trab group compared to the SC-based glaucoma surgery group (15.4% [93/604] vs 11.9% [72/604], respectively, and p = 0.045). Uncontrolled intraocular pressure (IOP) was the primary indication for reoperations in both groups. Trab surgery, higher preoperative IOP, greater number of preoperative medications, and previous glaucoma surgery history were independent risk factors for reoperation.
CONCLUSIONS
SC-based glaucoma surgery showed a…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 137 participants or records.
Read the paper
Related studies
- Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- A meta‐analysis of anal cancer incidence by risk group: Toward a unified anal cancer risk scale
- Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials
- Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis
- Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.