Haemodynamic and impedenzometric profile in low-risk pregnant women at term with excessive gestational weight gain: a pilot study
Abstract
Objective. We showed that excessive GWG (eGWG) associates with adverse outcomes among low-risk pregnancies, similarly to women with excessive pregestational BMI (epBMI). Yet, the underlying mechanisms are still unclarified. We hypothesized that abnormalities in hae-modynamics and body composition could play a potential role. Materials and Methods. A prospective cohort study including women with a singleton, low-risk gestation at term (11/2021-3/2023). Maternal haemodynamics and body composition were evaluated by USCOM-1A and impedance balance Inbody 270. GWG was defined according to 2009 NAM guideline. Women with normal pBMI (npB-MI 18.5-24.9 Kg/m 2 ) and adequate (aGWG) or excessive GWG (eGWG) were considered. Also, we included women with epBMI (≥ 25 Kg/m 2 ) and eGWG (epBMI/GWG). Results. We enrolled 147 npBMI women: 88 aGWG and 59 eGWG. Twenty-four patients showed epBMI/GWG. Gestational age at enrollment was 38-41 weeks. As compared to aGWG, women with eGWG showed higher SV and CO MoM (0.67 versus 0.60, p = 0.004; 0.72 versus 0.63, p = 0.001), with values similar
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 147 participants or records.
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