Calculation of Embryo/Fetus Dose in Pregnant Thyroid Patients Who Have Accidentally Received Radioiodine
Abstract
Objective: The aim of this study was to calculate the embryo/fetus dose in pregnant patients who have accidentally received radioiodine ( 131 I) and to evaluate the termination of pregnancy by giving teratological advice to the family.Methods: In this study, fetus dose was calculated in 16 patients who were referred to our department following the application of 131 I radioisotope for diagnosis and treatment in different nuclear medicine centers.Results: Mean embryo/fetus dose of three pregnant patients, who received 0.37 MBq (10 μCi) 131 I orally for thyroid uptake test, was calculated as 0.063 mGy.For uptake/ scintigraphy test, 1.85 MBq (0.05 mCi) 131 I was applied to six patients, and the calculated mean fetal dose was 0.13 mGy and fetal thyroid dose was 1073 mGy (1.073 Gy).Mean embryo/fetus dose of three patients who received mean 185 MBq (5 mCi) 131 I orally for whole body scintigraphy was calculated as 13.2 mGy.One of two patients with hyperthyroidism was administered 370 MBq (10 mCi) 131 I orally and the embryo/fetus dose was calculated as 26.64 mGy and fetal thyroid dose was calculated as 215340 mGy (215.34Gy).The other patient with hyperthyroidism received 481 MBq (13 mCi) 131 I and embryo/fetus dose was calculated as 34.63 mGy.One of two patients diagnosed with thyroid cancer received 3700 MBq (100 mCi) 131 I and the embryo/fetus dose was calculated as 266.64 mGy.The other patient with thyroid cancer received 5555 MBq (150 mCi) 131 I at 15 th gestational week, and…
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