Radiobiological Foundation of Crew Radiation Risk for Mars Mission to the Problem of the Space Flight Safety
Abstract
This paper presents results of radiobiological experiments, a new concept of radiation hazard on the basis of a generalized dosimetric function, which are foundation of crew radiation risk for Mars mission. The results of 14-year biological experiment on comprehensive clinico-physiological study of 250 dogs exposure to gamma-radiation 60Co during 3 and 6 years 22 hours per day, modeling the impact of space radiation on the crew of a space shuttle flight to Mars are presented also. In this experiment dose and dose rate varied to simulate galactic cosmic ray (GCR) dose and dose from stochastic irradiation caused by solar cosmic rays (SCR). It details observations made on the animals throughout the course of the dogs’ lives, both during and eight years after radiation exposure. It includes data on dose dependence, threshold levels of radiation causing adverse health effects, as well as on the nature of radiation reactions as they develop in different organs and body systems chronically exposed to larger doses. This multi-year experiment was conducted by scientists of the State Research Center Institute of Biomedical Problems (Russian Academy of Sciences) with the active participation of the Institute of Biophysics (now Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency). Based on results obtained in this study and in experiments realized with big amount of small laboratory animals that were exposed to a wide dose and dose rate range, using other…
Read the paper
Related studies
- Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- A meta‐analysis of anal cancer incidence by risk group: Toward a unified anal cancer risk scale
- Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials
- Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis
- Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.