Assessment of Radiation Risks of Mortality from Circulatory System Diseases in the Cohort of Liquidators of the Consequences of the Accident at the Chernobyl Nuclear Power Plant, Considering the Influence of Other Diseases Identified During the Observation Period
Abstract
Purpose: To assess the radiation risk of mortality from circulatory system diseases (CSD) in the cohort of liquidators of the consequences of the Chernobyl accident, considering the impact of other diseases detected in them during the observation period. Material and methods: Radiation risks of mortality from CSD were studied in the cohort of liquidators of the consequences of the Chernobyl accident observed in the National Radiation and Epidemiological Register (NRER) system from 1986 to 2022. The studied deaths are included in the codes I00–I99 of the International Statistical Classification of Diseases of the 10th Revision (ICD-10). Among the 89,594 members of the studied cohort, 16,780 deaths from CSD were identified. Mean age at the beginning of exposure was 34 years, the average absorbed dose of external gamma exposure of the whole body was 0.133 Gy, the maximum dose was 1.5 Gy, the average duration of exposure was 2.6 months. To analyze the dependence of the radiation risk of mortality from CSD on the presence of other diseases in them, regression models of excess relative risk (ERR) and nonparametric relative risk (RR) estimates in dose groups were used. Results: The average estimate of the excess relative risk ratio ERR/Gy=0.53 for the entire cohort, which is quantitatively comparable to the previously obtained estimate of ERR/Gy=0.74 for mortality from solid malignancies in the same cohort. The assessment of the radiation risk of mortality from CSD in the cohort of…
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