Browse studies, page 1061

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• Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged ≥ 65 years) with inadequately controlled type 2 diabetes mellitus Clinical interventions in aging, 2013
• Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes Postgraduate medicine, 2011
• Efficacy and safety of linagliptin in subjects with type 2 diabetes mellitus and poor glycemic control: pooled analysis of data from three placebo-controlled phase III trials Journal of diabetes and its complications, 2013
• Effects of acarbose and metformin on thyroid function and thyroid hormone sensitivity in type 2 diabetes patients: a post-hoc analysis of the MARCH study Journal of endocrinological investigation, 2025
• Effects of tirzepatide versus insulin glargine on kidney outcomes in type 2 diabetes in the SURPASS-4 trial: post-hoc analysis of an open-label, randomised, phase 3 trial The lancet. Diabetes & endocrinology, 2022
• Efficacy and safety of add on therapy of bromocriptine with metformin in Indian patients with type 2 diabetes mellitus: A randomized open labeled phase IV clinical trial Indian Journal of Pharmacology, 2014
• Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention Diabetologia, 2023
• The comparison of fennel infusion plus dry cupping versus metformin in management of oligomenorrhoea in patients with polycystic ovary syndrome: a randomised clinical trial Journal of Obstetrics and Gynaecology Research, 2019
• Effect of probiotics combined with metformin on improvement of menstrual and metabolic patterns in women with polycystic ovary syndrome: a randomized clinical trial Gynecological Endocrinology, 2022
• Metformin to Inhibit Progression of Abdominal Aortic Aneurysm: A Randomised, Placebo Controlled Clinical Trial European Journal of Vascular and Endovascular Surgery, 2025
• Bilayer matrix tablets for prolonged actions of metformin hydrochloride and repaglinide AAPS PharmSciTech, 2015
• A multicenter, open-label phase II study of metformin with erlotinib in second-line therapy of stage IV non-small-cell lung cancer patients: treatment rationale and protocol dynamics of the METAL trial Clinical lung cancer, 2015
• Reversal of increased lymphocyte PC-1 activity in patients with type 2 diabetes treated with metformin Diabetes/metabolism research and reviews, 1999
• One Bout of Resistance Training Does Not Enhance Metformin Actions in Prediabetic and Diabetic Individuals Medicine and science in sports and exercise, 2022
• Adjunctive Probio-X Treatment Enhances the Therapeutic Effect of a Conventional Drug in Managing Type 2 Diabetes Mellitus by Promoting Short-Chain Fatty Acid-Producing Bacteria and Bile Acid Pathways mSystems, 2023
• Pharmacokinetic comparison of gemigliptin 50 mg and metformin 500 mg as a fixed-dose combination and loose combination . International journal of clinical pharmacology and therapeutics, 2019
• Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome GeroScience, 2025
• Factors that influence the efficacy of acarbose and metformin as initial therapy in Chinese patients with newly diagnosed type 2 diabetes: a subanalysis of the MARCH trial Current medical research and opinion, 2016
• Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications Amino acids, 2018
• Cardiometabolic risk factors, peripheral arterial tonometry and metformin in adults with type 1 diabetes participating in the REducing with MetfOrmin Vascular Adverse Lesions trial Diabetes & vascular disease research, 2023
• Phase II study of medroxyprogesterone acetate plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer Annals of oncology : official journal of the European Society for Medical Oncology, 2016
• Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer Cell metabolism, 2018
• Comparison of bedtime NPH insulin or metformin combined with glibenclamide in secondary sulphonylurea failure in obese type II (NIDDM) patients JPMA. The Journal of the Pakistan Medical Association, 1998
• Metformin is effective in achieving biochemical response in patients with nonalcoholic fatty liver disease (NAFLD) not responding to lifestyle interventions Annals of hepatology, 2007
• Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes Diabetologia, 2004
• The effect of ethinylestradiol (EE)/cyproterone acetate (CA) and EE/CA plus metformin treatment on adhesion molecules in cases with polycystic ovary syndrome (PCOS) Internal medicine (Tokyo, Japan), 2009
• Effect of metformin glycinate on glycated hemoglobin A1C concentration and insulin sensitivity in drug-naive adult patients with type 2 diabetes mellitus Diabetes technology & therapeutics, 2012
• Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production Diabetes, 1994
• Effect on glycemic control of the addition of 2.5 mg glipizide GITS to metformin in patients with T2DM. Diabetes research and clinical practice, 2005
• More effective glycaemic control by metformin in African Americans than in Whites in the prediabetic population Diabetes & metabolism, 2015
• Effects of lifestyle modification and metformin on atherosclerotic indices among HIV-infected patients with the metabolic syndrome AIDS (London, England), 2012
• Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS) The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2001
• Costs associated with the primary prevention of type 2 diabetes mellitus in the diabetes prevention program Diabetes care, 2003
• A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease The American journal of gastroenterology, 2005
• Effects of pioglitazone and metformin on beta-cell function in nondiabetic subjects at high risk for type 2 diabetes American journal of physiology. Endocrinology and metabolism, 2007
• The effect of metformin in overweight patients with type 1 diabetes and poor metabolic control Basic & clinical pharmacology & toxicology, 2009
• Repurposing Metformin for periodontal disease management as a form of oral-systemic preventive medicine Journal of translational medicine, 2023
• Short-term Metformin Protects Against Glucocorticoid-Induced Toxicity in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial Diabetes care, 2025
• Comparative study of low-dose pioglitazone or metformin treatment in Japanese diabetic patients with metabolic syndrome Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2009
• Determinants of maternal triglycerides in women with gestational diabetes mellitus in the Metformin in Gestational Diabetes (MiG) study Diabetes care, 2013
• Metformin ameliorates the proinflammatory state in patients with carotid artery atherosclerosis through sirtuin 1 induction Translational research : the journal of laboratory and clinical medicine, 2015
• Phase 1 and Pharmacokinetic Drug-Drug Interaction Study of Metformin, Losartan, and Linagliptin Coadministered With DW1029M in Healthy Volunteers Clinical pharmacology in drug development, 2017
• The Effect of Eighteen-Month Metformin Treatment in Obese Adolescents: Comparison of Results Obtained in Daily Practice with Results from a Clinical Trial Journal of obesity, 2016
• Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome Fertility and sterility, 1998
• Effect of lifestyle adjustment, metformin and rosiglitazone in polycystic ovary syndrome Zhonghua fu chan ke za zhi, 2007
• Adiponectin levels in women with polycystic ovary syndrome: impact of metformin treatment in a randomized controlled study Fertility and sterility, 2010
• Metformin reduces vascular endothelial dysfunction caused by an acute glucose load in patients with hypertension Blood pressure, 2013
• The effect of alfacalcidiol and metformin on phenotype manifestations in women with polycystic ovary syndrome - a preliminary study Physiological research, 2016
• Metformin treatment of antipsychotic-induced dyslipidemia: analysis of two randomized, placebo-controlled trials Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2019
• Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes Diabetes care, 2012
• Metformin decreases serum 8-hydroxy-2'-deoxyguanosine levels in polycystic ovary syndrome Fertility and sterility, 2013
• Efficacy and safety of fixed-dose combination therapy, alogliptin plus metformin, in Asian patients with type 2 diabetes: A phase 3 trial Diabetes, obesity & metabolism, 2017
• Metformin extended-release versus immediate-release: An international, randomized, double-blind, head-to-head trial in pharmacotherapy-naïve patients with type 2 diabetes Diabetes, obesity & metabolism, 2018
• Efficacy of imeglimin treatment versus metformin dose escalation on glycemic control in subjects with type 2 diabetes treated with a dipeptidyl peptidase-4 inhibitor plus low-dose metformin: A multicenter, prospective, randomized, open-label, parallel-group comparison study (MEGMI study) Diabetes, obesity & metabolism, 2025
• Impact of metformin therapy in patients with polycystic ovarian syndrome Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005
• Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS) Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017
• Oral antidiabetic combination therapy with sulphonylureas and metformin Diabete & metabolisme, 1991
• Responsiveness to metformin in girls with androgen excess: collective influence of genetic polymorphisms Fertility and sterility, 2011
• Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial Reproductive sciences (Thousand Oaks, Calif.), 2013
• Efficacy of metformin on postprandial plasma triglyceride concentration by administration timing in patients with type 2 diabetes mellitus: A randomized cross-over pilot study Journal of diabetes investigation, 2019
• Effect of insulin aspart combined with insulin detemir and metformin on islet function in newly diagnosed type 2 diabetes mellitus Journal of drug targeting, 2025
• Results of a placebo-controlled study of the metabolic effects of the addition of metformin to sulfonylurea-treated patients. Evidence for a central role of adipose tissue Diabetes care, 1997
• Limited sampling strategy for determining metformin area under the plasma concentration-time curve British journal of clinical pharmacology, 2016
• Metformin in obese pregnancy has no adverse effects on cardiovascular risk in early childhood Journal of developmental origins of health and disease, 2022
• Vildagliptin compared to glimepiride on post-prandial lipemia and on insulin resistance in type 2 diabetic patients Metabolism: clinical and experimental, 2014
• Metformin and longevity (METAL): a window of opportunity study investigating the biological effects of metformin in localised prostate cancer BMC cancer, 2017
• Metformin decreases glycated albumin to glycated haemoglobin ratio in patients with newly diagnosed type 2 diabetes Annals of clinical biochemistry, 2015
• Effect of Exercise Versus Metformin among Nigerians with Prediabetes: A Randomised Controlled Trial West African journal of medicine, 2024
• Effects of short-term metformin therapy associated with levothyroxine dose decrement on TSH and thyroid hormone levels in patients with thyroid cancer Minerva endocrinologica, 2014
• Assessment of safety and tolerability of remogliflozin etabonate (GSK189075) when administered with total daily dose of 2000 mg of metformin BMC pharmacology & toxicology, 2021
• Effects of metformin combined with cyproterone acetate on clinical features, endocrine and metabolism of non-obese women with polycystic ovarian syndrome Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005
• Does metformin increase paraoxonase activity in patients with the metabolic syndrome? Additional data from the MEFISTO study Clinical and translational science, 2012
• A double-blind randomized study comparing the effects of continuing or not continuing rosiglitazone + metformin therapy when starting insulin therapy in people with Type 2 diabetes Diabetic medicine : a journal of the British Diabetic Association, 2007
• (Ir)relevance of Metformin Treatment in Patients with Metastatic Pancreatic Cancer: An Open-Label, Randomized Phase II Trial Clinical cancer research : an official journal of the American Association for Cancer Research, 2016
• Glyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study Diabetes care, 2017
• Effect of Metformin on Microvascular Endothelial Function in Polycystic Ovary Syndrome Mayo Clinic proceedings, 2019
• Sustained benefits of metformin therapy on markers of cardiovascular risk in human immunodeficiency virus-infected patients with fat redistribution and insulin resistance The Journal of clinical endocrinology and metabolism, 2002
• Acute effect of metformin on exercise capacity in active males Diabetes, obesity & metabolism, 2008
• Comparison of the effects of sibutramine versus sibutramine plus metformin in obese women Clinical and experimental medicine, 2010
• A randomized, double-blind, comparative therapy evaluating sitagliptin versus glibenclamide in type 2 diabetes patients already treated with pioglitazone and metformin: a 3-year study Diabetes technology & therapeutics, 2013
• Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial Breast cancer research and treatment, 2014
• Efficacy and safety of liraglutide monotherapy compared with metformin in Japanese overweight/obese patients with type 2 diabetes Endocrine journal, 2015
• Twice-daily dosing of a repaglinide/metformin fixed-dose combination tablet provides glycaemic control comparable to rosiglitazone/metformin tablet Diabetes, obesity & metabolism, 2009
• The effect of metformin on ovarian stimulation and in vitro fertilization in insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross-over trial Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2003
• High neutrophil count in girls and women with hyperinsulinaemic hyperandrogenism: normalization with metformin and flutamide overcomes the aggravation by oral contraception Human reproduction (Oxford, England), 2005
• Metformin for metabolic dysregulation in schizophrenic patients treated with olanzapine Progress in neuro-psychopharmacology & biological psychiatry, 2008
• Insulin-Like Growth Factor 1/Mammalian Target of Rapamycin and AMP-Activated Protein Kinase Signaling Involved in the Effects of Metformin in the Human Endometrial Cancer International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2016
• Anti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer Gynecologic oncology, 2014
• Bioequivalence of Dapagliflozin/Metformin Extended-release Fixed-combination Drug Product and Single-component Dapagliflozin and Metformin Extended-release Tablets in Healthy Russian Subjects Clinical therapeutics, 2018
• Effects of Metformin on Spatial and Verbal Memory in Children with ASD and Overweight Associated with Atypical Antipsychotic Use Journal of child and adolescent psychopharmacology, 2018
• Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects Journal of Korean medical science, 2018
• Benefits of metformin add-on insulin therapy (MAIT) for HbA1c and lipid profile in adolescents with type 1 diabetes mellitus: preliminary report from a double-blinded, placebo-controlled, randomized clinical trial Journal of pediatric endocrinology & metabolism : JPEM, 2022
• Therapeutic effect of metformin on reversing gastric intestinal metaplasia Chinese medical journal, 2026
• Effects of metformin on gonadotropin-induced ovulation in women with polycystic ovary syndrome Fertility and sterility, 1999
• The effect of metformin on fat distribution and the metabolic syndrome in women with polycystic ovary syndrome--a randomised, double-blind, placebo-controlled trial BJOG : an international journal of obstetrics and gynaecology, 2006
• Metformin has no major effects on glucose homeostasis in pregnant women with PCOS: results of a randomized double-blind study Scandinavian journal of clinical and laboratory investigation, 2008
• Pharmacokinetic Variables of Dapagliflozin/Metformin Extended-release Fixed-dose Combination in Healthy Chinese Volunteers and Regional Comparison Clinical therapeutics, 2023
• Lispro insulin and metformin versus other combination in the diabetes mellitus type 2 management after secondary oral antidiabetic drug failure Collegium antropologicum, 2003
• 2-year effects of pioglitazone add-on to sulfonylurea or metformin on oral glucose tolerance in patients with type 2 diabetes Diabetes research and clinical practice, 2008
• Effects of metformin and ethinyl estradiol-cyproterone acetate on clinical, endocrine and metabolic factors in women with polycystic ovary syndrome Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2008