Browse studies, page 259

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• Chronic Sildenafil for Severe Diaphragmatic Hernia ClinicalTrials.gov · TERMINATED, 2013
• A Double-Blind, Placebo-Controlled, Cross-Over Study of Sildenafil (Viagra) for the Treatment of Dyskinesias in Parkinson's Disease ClinicalTrials.gov · TERMINATED, 2009
• Hemodynamic Effects of Acute Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension: Single-center Randomized Controlled Trial ClinicalTrials.gov · COMPLETED, 2023
• Evaluation of the Efficacy of Sildenafil on Time to Healing in Patients With Scleroderma and Ischaemic Digital Ulcers: a Prospective, Longitudinal, Randomized, Comparative, Double-blind, 2-parallel-arm, Placebo-controlled Study ClinicalTrials.gov · COMPLETED, 2013
• Sildenafil for Improving Outcomes After Valvular Correction ClinicalTrials.gov · COMPLETED, 2016
• A Phase 1, Open-Label Study of Intravenous Sildenafil in Patients With Cirrhosis ClinicalTrials.gov · TERMINATED, 2015
• An International, Multicentre, Randomized, Parallel Group, Double Blind, Placebo Controlled, Flexible Dose Study to Evaluate Self-esteem and Relationships in Males With Erectile Dysfunction Treated With Sildenafil Citrate ClinicalTrials.gov · COMPLETED, 2004
• 9 wk, Randomized, 2-blind, Placebo-controlled, 2X2 Cross-over Phase 1 Study of 25 mg of Scelectium Tortuosum (as Zembrin®) in Aged Normals to Find Effects on Mental, Emotional and Cognitive Safety Measures and Cytokines ClinicalTrials.gov · COMPLETED, 2012
• A Randomized, Double-blind, Placebo Controlled, Parallel Arm, Multicenter Trial Assessing the Effect of Daily Treatment of Vardenafil 20 mg or Sildenafil 100 mg Compared to Placebo on Spermatogenesis ClinicalTrials.gov · COMPLETED, 2006
• Does Sildenafil Improve Endothelial Dysfunction in Rheumatoid Arthritis? ClinicalTrials.gov · TERMINATED, 2020
• Sildenafil for Fontan Associated Liver Disease (SiFALD) Study ClinicalTrials.gov · COMPLETED, 2019
• The Impact of Using Platelet-Rich Plasma Versus Granulocyte Colony-Stimulating Factor Versus Placebo on the Outcomes of Frozen Embryo Transfer: A Double Blind Randomized Controlled Trial ClinicalTrials.gov · COMPLETED, 2023
• Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart Disease ClinicalTrials.gov · TERMINATED, 2013
• Pilot of Oral Sildenafil for the Treatment of Pulmonary Hypertension in Thalassemia With Comparison to Controls ClinicalTrials.gov · COMPLETED, 2010
• Effects of the Dive Reflex on Pulmonary Arterial and Pulmonary Artery Wedge Pressures in Subjects Who Have Experienced Immersion Pulmonary Edema ClinicalTrials.gov · COMPLETED, 2015
• Acute Effects of Sildenafil on Flow Mediated Dilatation and Cardiovascular Autonomic Nerve Function in Type 2 Diabetic Patients ClinicalTrials.gov · COMPLETED, 2003
• Effect of Sildenafil for the Treatment of Sustained Pulmonary Artery Hypertension After Corrected Mitral Valve Disease ClinicalTrials.gov · TERMINATED, 2018
• Pharmacokinetics of Sildenafil Following Administration of an Chewable Tablet of Sildenafil Relative to Viagra® Conventional Oral Tablet in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2011
• The Role of Phosphodiesterase Inhibitors in CF Lung Disease ClinicalTrials.gov · COMPLETED, 2012
• Satisfaction With the Treatment, Confidence and Naturalness in Engaging in Sexual Activity in Men With Psychogenic Erectile Dysfunction: Randomized Controlled Trial of Three Therapeutic Approaches ClinicalTrials.gov · COMPLETED
• Effectiveness Of An Educational Program To Improve Patients' Satisfaction Regarding Their Management Of Erectile Dysfunction With Sildenafil ClinicalTrials.gov · COMPLETED, 2003
• Pulmonary Vasodilation by Sildenafil in Acute Pulmonary Embolism ClinicalTrials.gov · COMPLETED, 2018
• A Pharmacoscintigraphic Clinical Study to Evaluate a Biphasic Release Sildenafil Formulation (With Immediate and Sustained Release Components) Compared to a Marketed Sildenafil Product in Fed and Fasted States ClinicalTrials.gov · COMPLETED, 2018
• Oral Sildenafil Citrate: a Potential Approach for Improvement of Endometrial Thickness and Treatment of Unexplained Infertility in Women ClinicalTrials.gov · COMPLETED, 2022
• Phase 1, Open-Label, Randomized, Single-Dose, 3-Way Crossover Study Assessing Bioequivalence Of Sildenafil 50 Mg Orally-Disintegrating Tablet With Or Without Water To Viagra® 50 Mg Oral Tablet With Water Under Fasted Condition ClinicalTrials.gov · COMPLETED, 2012
• A Randomized, Double-Blinded, Placebo-Controlled, Two-Way Crossover Study to Investigate The Safety And Toleration Of Single Dose Sildenafil In Subjects Receiving Chronic UK-369,003 ClinicalTrials.gov · COMPLETED, 2008
• A Multicenter, Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Flexible-Dose Study To Assess The Efficacy And Safety Of Viagra (Sildenafil Citrate) In Men With Erectile Dysfunction (ED) Who Do Not Self Identify ClinicalTrials.gov · COMPLETED, 2007
• Evaluation of Endothelial and Hemodynamic Function in HIV Associated Pulmonary Hypertension and a Phase I/II Safety and Efficacy Trial of Sildenafil in HIV Associated Pulmonary Hypertension ClinicalTrials.gov · TERMINATED, 2009
• A Multicenter, Double-blind, Randomized Study Comparing the Safety and Tolerability of Iloprost Inhalation Solution Delivered by I-neb Utilizing Power Disc-15 and Power Disc-6 in Patients With Symptomatic Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2010
• An Interaction Study to Evaluate Changes in Blood Pressure Following 1, 1.5, 2, and 2.5 mg Riociguat Tid (Dose Titration) Compared to Placebo Treatment on the Background of Stable Sildenafil Pretreatment in Subjects With Symptomatic Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2013
• Effect of Sildenafil Citrate on Uteri- Placental Perfusion, Doppler Indices in Growth Restricted Fetuses ClinicalTrials.gov · COMPLETED, 2016
• The Dutch STRIDER (Sildenafil TheRapy In Dismal Prognosis Early-onset Fetal Growth Restriction) ClinicalTrials.gov · TERMINATED, 2018
• Pulmonary Hypertension Secondary to Heart Failure With Preserved Systolic Function: a Target of Phosphodiesterase - 5 Inhibition in a 1- Year Duration Study ClinicalTrials.gov · COMPLETED, 2009
• This Protocol is a Randomized Prospective Study Comparing Prophylactic and on Demand Sildenafil Citrate Usage Administered During and After Radiotherapy With or Without Hormone Therapy Versus Radiotherapy With or Without Hormone Therapy Alone for the Preservation of Erectile Function After Therapy for Potent Patients With Clinically Localized Prostate Cancer ClinicalTrials.gov · COMPLETED, 2014
• Effect of Nebivolol on Blood Pressure in a Model of Hypertension Sensitive to Potentiation of Nitric Oxide Bioactivity ClinicalTrials.gov · COMPLETED, 2014
• A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Safety And Efficacy Study Of Sitaxsentan Sodium In Subjects With Pulmonary Arterial Hypertension ClinicalTrials.gov · TERMINATED, 2011
• Renin-Angiotensin Aldosterone System and Fibrinolysis(RAAS) Interaction in Humans- Specific Aim 3 ClinicalTrials.gov · COMPLETED, 2009
• Smoking Cessation and Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema ClinicalTrials.gov · COMPLETED, 2024
• A Randomized, Double-blind, Parallel-group, Placebo-controlled Study Evaluating the Efficacy and Safety of Vardenafil Administered for 12 Weeks in a Flexible-dose Regimen Compared to Placebo in Male Erectile Dysfunction Subjects ClinicalTrials.gov · COMPLETED, 2003
• A Non-randomised Controlled Trial of Early Intervention to Preserve Erectile Function After Laparoscopic Resection for Rectal Cancer ClinicalTrials.gov · COMPLETED, 2015
• A Multi-center, Prospective, Randomized, Double-blind, Flexible-dose, Placebo-controlled, Parallel Group Clinical Trial of Sildenafil Oral Film 25 mg, 50 mg, 75 mg and 100 mg for the Treatment of Erectile Dysfunction (ED) ClinicalTrials.gov · COMPLETED, 2024
• A Phase 1, Open-Label, Within-Subject Dose-Escalation Study to Evaluate the Clinical Vulvar-Vaginal Safety and Pharmacokinetic Profile of SST-6006, a Topical Sildenafil Cream (5% w/w), in Healthy Postmenopausal Women ClinicalTrials.gov · COMPLETED, 2015
• Combined Clinical and Surgical Approaches to Congenital Heart Disease Associated With Pulmonary Arterial Hypertension (PAH-CHD) ClinicalTrials.gov · COMPLETED, 2020
• Sildenafil and Stroke Recovery ClinicalTrials.gov · TERMINATED, 2016
• Functional Muscle Ischemia and PDE5 Inhibition in Duchenne Muscular Dystrophy: Acute Dosing Study ClinicalTrials.gov · COMPLETED
• Role of Blood Flow and Vascular Function on Exercise Capacity in Cystic Fibrosis ClinicalTrials.gov · COMPLETED, 2018
• Development and Clinical Evaluation of Thermosensitive Gels for the Vaginal Delivery of Sildenafil Citrate on the Endometrium of Women Use Clomiphene Citrate for Induction of Ovulation ClinicalTrials.gov · COMPLETED, 2015
• A Double-blind, Randomized, Crossover Evaluation of the Hemodynamic Response to Sublingual Glyceryl Trinitrate in Patients Receiving TA-1790, Sildenafil, and Placebo ClinicalTrials.gov · COMPLETED, 2004
• Safety and Pharmacokinetic Comparison of Sildenafil ODF and FCT Formulations in Healthy Korean Volunteers ClinicalTrials.gov · COMPLETED, 2011
• A Multicenter, Double-blind, Randomized, Placebo-controlled, Crossover Study to Assess the Effects of a Single Dose of Iloprost Power 15 on Exercise Capacity in Patients With Symptomatic Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2009
• A Non-Randomized, Multiple Dose, Three Treatment Period, Open-Label, Single Sequence, Single Group Study to Evaluate the Pharmacokinetic Effect of Two Doses of QTI571 (Imatinib) on the Co-administered Drugs Sildenafil and Bosentan in Pulmonary Arterial Hypertension (PAH) Patients ClinicalTrials.gov · COMPLETED, 2012
• Erectile Dysfunction Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted Prostatectomy (BNS-RAP) for Prostate Cancer ClinicalTrials.gov · TERMINATED, 2012
• A Randomized, Double-Blind, Placebo Controlled, Dose Ranging, Parallel Group Study of Oral Sildenafil in the Treatment of Children, Aged 1-17 Years, With Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2008
• The Effect of Sildenafil on Diffusion Capacity Measurements in Patients With Pulmonary Hypertension and Parenchymal Lung Disease ClinicalTrials.gov · COMPLETED, 2012
• Therapy of Pulmonary Arterial Hypertension (PAH) - Treatment With Sildenafil in Eisenmenger Patients ClinicalTrials.gov · TERMINATED, 2012
• An Open Label Crossover Study In Healthy Older Male Subjects To Evaluate The Pharmacokinetics And Safety Of Sildenafil Following Fasted Administration Of An Orally Disintegrating Tablet Formulation Of Sildenafil Administered With Or Without Water Relative To Viagra® Oral Tablet With Water ClinicalTrials.gov · COMPLETED, 2011
• A Multi-Center, Flexible Dose Study With A Double-Blind, Randomized, Placebo-Controlled Phase Followed By An Open-Label Phase To Evaluate The Impact Of Treatment With Sildenafil Citrate On The Symptoms Of Depression And Quality Of Life (Qol) Of Male Patients With Erectile Dysfunction (ED) ClinicalTrials.gov · COMPLETED, 2004
• Cerebrovascular Reactivity Assessed With Functional Near-infrared Spectroscopy and Magnetic Resonance Imaging as a Biomarker of Traumatic Microvascular Injury in American Football Players ClinicalTrials.gov · TERMINATED, 2022
• Effect of Sildenafil on Digital Ulcers in Systemic Sclerosis ClinicalTrials.gov · COMPLETED, 2007
• Improving Right Ventricular Function in Young Adults Born Preterm: A Pilot Study ClinicalTrials.gov · COMPLETED, 2020
• Influence of the Nitric Oxide Synthase T-786C Polymorphism on the Response to Acute Inhibition of Phosphodiesterase 5 in Resistant Hypertension ClinicalTrials.gov · COMPLETED, 2012
• Efficacy of Sildenafil Citrate to Reduce the Rate of Cesarean Section for Intrapartum Fetal Distress During Induction of Labor ClinicalTrials.gov · COMPLETED, 2022
• Etude préliminaire Sur l'efficacité Aigue du Sildenafil Sur le Temps de Marche Chez Les Patients Atteints d'AOMI de Stade II présentant Une Claudication artérielle ClinicalTrials.gov · COMPLETED, 2017
• Motor Response to Acute Challenge to Sildenafil in Parkinsons Disease ClinicalTrials.gov · COMPLETED, 2004
• Effects of Daily Tadalafil on Body Composition in Men With Sexual Distress ClinicalTrials.gov · COMPLETED, 2015
• Pharmacokinetics of Sildenafil in Premature Infants ClinicalTrials.gov · COMPLETED, 2016
• Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX) ClinicalTrials.gov · COMPLETED, 2012
• Effects of Low-intensity Shockwave Therapy Versus Kegel Exercises on Arteriogenic Erectile Dysfunction in Diabetic Patients ClinicalTrials.gov · COMPLETED, 2024
• Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers Syndrome ClinicalTrials.gov · COMPLETED, 2008
• An Open-Label, Crossover Study In Healthy Volunteers To Evaluate The Pharmacokinetics Of Sildenafil Following Administration Of Three Orally Disintegrating Tablet Formulations Of Sildenafil Without Water Relative To Viagra Conventional Oral Tablet With Water ClinicalTrials.gov · COMPLETED, 2009
• Pilot Open-label Trial of Nivolumab Combined With Chemotherapy in Refractory Myelodysplastic Syndromes ClinicalTrials.gov · TERMINATED, 2018
• PDE5 inhibitor sildenafil in the treatment of heart failure: a meta-analysis of randomized controlled trials International Journal of Cardiology, 2014
• Randomized Controlled Trial of Sildenafil for Preventing Recurrent Ischemic Priapism in Sickle Cell Disease American Journal of Medicine, 2014
• Sildenafil Mediates Blood-Flow Redistribution and Neuroprotection After Neonatal Hypoxia-Ischemia Stroke, 2014
• An open-label study to evaluate sildenafil for the treatment of lymphatic malformations Journal of American Academy of Dermatology, 2014
• STRIDER: Sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction – a protocol for a systematic review with individual participant data and aggregate data meta-analysis and trial sequential analysis Systematic Reviews, 2014
• Sildenafil use and increased risk of incident melanoma in US men: a prospective cohort study JAMA Internal Medicine, 2014
• Sildenafil Improves Exercise Hemodynamics in Fontan Patients Circulation Cardiovascular Imaging, 2014
• A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis New England Journal of Medicine, 2010
• Impact of Mitochondrial Ca2+-Sensitive Potassium (mBKCa) Channels in Sildenafil-Induced Cardioprotection in Rats PLoS ONE, 2015
• Sildenafil reduces signs of oxidative stress in pulmonary arterial hypertension: Evaluation by fatty acid composition, level of hydroxynonenal and heart rate variability Redox Biology, 2015
• Sildenafil Ameliorates Long Term Peripheral Neuropathy in Type II Diabetic Mice PLoS ONE, 2015
• Treatment with Sildenafil Improves Insulin Sensitivity in Prediabetes: A Randomized, Controlled Trial Journal of Clinical Endocrinology and Metabolism, 2015
• Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95 OncoTarget, 2015
• Effect of Sildenafil on Pre-Eclampsia-Like Mouse Model Induced By L-Name Reproduction in domestic animals = Zuchthygiene, 2015
• Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure With Preserved Ejection Fraction Circulation: Heart Failure, 2015
• Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms Journal of Neuroinflammation, 2015
• Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study Annals of the Rheumatic Diseases, 2015
• PATENT PLUS: a blinded, randomised and extension study of riociguat plus sildenafil in pulmonary arterial hypertension European Respiratory Journal, 2015
• Bosentan added to sildenafil therapy in patients with pulmonary arterial hypertension European Respiratory Journal, 2015
• Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis Drug Design, Development and Therapy, 2016
• Clinically relevant timing of antenatal sildenafil treatment reduces pulmonary vascular remodeling in congenital diaphragmatic hernia American Journal of Physiology - Lung cellular and Molecular Physiology, 2016
• Sildenafil, a cyclic GMP phosphodiesterase inhibitor, induces microglial modulation after focal ischemia in the neonatal mouse brain Journal of Neuroinflammation, 2016
• Phosphodiesterase Type 5 Inhibitor Sildenafil Decreases the Proinflammatory Chemokine CXCL10 in Human Cardiomyocytes and in Subjects with Diabetic Cardiomyopathy Inflammation, 2016
• Transplacental sildenafil rescues lung abnormalities in the rabbit model of diaphragmatic hernia Thorax, 2016
• Sildenafil treatment ameliorates the maternal syndrome of preeclampsia and rescues fetal growth in the Dahl Salt Sensitive rat HYPERTENSION, 2016
• Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth Cell Reports, 2016
• Impaired Right Ventricular-Pulmonary Arterial Coupling and Effect of Sildenafil in Heart Failure With Preserved Ejection Fraction: An Ancillary Analysis From the Phosphodiesterase-5 Inhibition to Improve Clinical Status And Exercise Capacity in Diastolic Heart Failure (RELAX) Trial Circulation: Heart Failure, 2016
• Perinatal and Hemodynamic Evaluation of Sildenafil Citrate for Preeclampsia Treatment: A Randomized Controlled Trial Obstetrics and Gynecology, 2016
• Swimming-Induced Pulmonary Edema: Pathophysiology and Risk Reduction With Sildenafil Circulation, 2016