Browse studies, page 822
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- Metformin has immunomodulatory effects which support its potential use as adjunctive therapy in tuberculosis The Indian journal of tuberculosis, 2024
- Metformin protects skeletal muscle from cardiotoxin induced degeneration PloS one, 2014
- Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a bladder cancer cell line PloS one, 2021
- The Antineoplastic Effect of Carboplatin Is Potentiated by Combination with Pitavastatin or Metformin in a Chemoresistant High-Grade Serous Carcinoma Cell Line International journal of molecular sciences, 2022
- The effects of metformin and simvastatin on the growth of LNCaP and RWPE-1 prostate epithelial cell lines European journal of pharmacology, 2016
- Effect of Sodium-Glucose Co-Transporter 2 Inhibitors Combined with Metformin on Pancreatic Cancer Cell Lines International journal of molecular sciences, 2024
- Metformin reduced the alkaline resistance of Enterococcus faecalis against calcium hydroxide via Man-PTS EII: in vitro and in vivo studies Clinical oral investigations, 2024
- Combining metformin and nelfinavir exhibits synergistic effects against the growth of human cervical cancer cells and xenograft in nude mice Scientific reports, 2017
- Preparation and in vitro/in vivo evaluation of metformin hydrochloride rectal dosage forms for treatment of patients with type II diabetes Journal of drug targeting, 2017
- Metformin induces caspase-dependent and caspase-independent apoptosis in human bladder cancer T24 cells Anti-cancer drugs, 2020
- Resistance to gemcitabine in the pancreatic cancer cell line KLM1-R reversed by metformin action Anticancer research, 2015
- Substrate-Dependent Inhibition of the Human Organic Cation Transporter OCT2: A Comparison of Metformin with Experimental Substrates PloS one, 2015
- Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation International journal of biological macromolecules, 2013
- GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate Cancer research, 2020
- Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC. Oncotarget, 2015
- Anti-proliferative effect of rosiglitazone in the human T-lymphocyte leukaemia cell line Jurkat cells Cell biology international, 2018
- Effect of metformin on dental pulp stem cells attachment, proliferation and differentiation cultured on biphasic bone substitutes Archives of oral biology, 2018
- Increased FoxM1 expression is a target for metformin in the suppression of EMT in prostate cancer International journal of molecular medicine, 2014
- Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer's-like changes Neuropharmacology, 2011
- Metabolic engineering of lactate dehydrogenase rescues mice from acidosis Scientific reports, 2014
- In Vitro Anti-Echinococcal and Metabolic Effects of Metformin Involve Activation of AMP-Activated Protein Kinase in Larval Stages of Echinococcus granulosus PloS one, 2015
- Sensitization to oxaliplatin in HCT116 and HT29 cell lines by metformin and ribavirin and differences in response to mitochondrial glutaminase inhibition Journal of cancer research and therapeutics, 2015
- AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity Diabetes, 2016
- Implementation of two different experimental designs for screening and optimization of process parameters for metformin-loaded carboxymethyl chitosan formulation Drug development and industrial pharmacy, 2019
- Metformin resistant MDA-MB-468 cells exhibit EMT-like phenotype and increased migration capacity Medical oncology (Northwood, London, England), 2022
- Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos Journal of assisted reproduction and genetics, 2016
- Metformin protects against diclofenac-induced toxicity in primary rat hepatocytes by preserving mitochondrial integrity via a pathway involving EPAC. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
- Protective effect of metformin against cisplatin-induced ototoxicity in an auditory cell line Journal of the Association for Research in Otolaryngology : JARO, 2014
- Effects of metformin and silodosin as supplementary treatments to abiraterone on human telomerase reverse transcriptase (hTERT) level in metastatic castration-resistant prostate cancer (mCRPC) cells: An in vitro study Narra J, 2024
- Targeted inhibition of JMJD2C/MALAT1 axis compensates for the deficiency of metformin in reversing ovarian cancer platinum resistance Life sciences, 2025
- Highlighting fibroblast plasticity in lung fibrosis: the WI-38 cell line as a model for investigating the myofibroblast and lipofibroblast switch Theranostics, 2024
- Effects of metformin on cell kinetic parameters of MCF-7 breast cancer cells in vitro Asian Pacific journal of cancer prevention : APJCP, 2015
- Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer PloS one, 2018
- Anti-diabetic drug metformin inhibits cell proliferation and tumor growth in gallbladder cancer via G0/G1 cell cycle arrest Anti-cancer drugs, 2020
- Investigation of the synergistic effect of metformin and FX11 on PANC-1 cell lines Biological research, 2025
- Late dual endothelin receptor blockade with bosentan restores impaired cerebrovascular function in diabetes Life sciences, 2014
- Re-evaluation of cytostatic therapies for meningiomas in vitro Journal of cancer research and clinical oncology, 2014
- AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell Cancer biology & therapy, 2015
- Protective effects of metformin in the pro-inflammatory cytokine induced intestinal organoids injury model Biochemical and biophysical research communications, 2024
- Elevation of miR-221 and -222 in the internal mammary arteries of diabetic subjects and normalization with metformin Molecular and cellular endocrinology, 2013
- Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles Nature Communications, 2021
- Metformin attenuates ventilator-induced lung injury Critical care (London, England), 2012
- Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK) The Journal of biological chemistry, 2014
- Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression Chemico-biological interactions, 2011
- Sex differences in cognition, anxiety-phenotype and therapeutic effect of metformin in the aged apoE-TR mice Biology of sex differences, 2025
- Colesevelam Hydrochloride Therapy in Patients With Type 2 Diabetes Mellitus Treated With Metformin Archives of Internal Medicine, 2008
- Glycated Hemoglobin and Prediabetes: A Systematic Review of HbA1c Thresholds for Type 2 Diabetes Prevention Journal of clinical medicine, 2026
- Design, Synthesis, and Biological Evaluation of Novel ML-167 Analogues as Therapeutic Candidates Against Sarcopenia-Induced Muscle Wasting Pharmaceuticals (Basel, Switzerland), 2026
- The Role of Sodium-Glucose Cotransporter 2 Inhibitors on Peripheral Nerves and Skeletal Muscle Function in Type 2 Diabetes Journal of the ASEAN Federation of Endocrine Societies, 2026
- Beta-Caryophyllene (BCP) Modulating the Endocannabinoid System and PPARγ to Combat Metabolic Dysregulation: A Narrative Review Therapeutics and clinical risk management, 2026
- Effects of metformin therapy on plasma amino acid pattern in patients with maturity-onset diabetes Drugs under experimental and clinical research, 1989
- Metformin and respiratory chain complex I: the last piece of the puzzle? The Biochemical journal, 2014
- Metformin's effect on 5-fluorouracil,cisplatin,paclitaxel in laryngocarcinoma Hep-2 cells Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery, 2017
- Influence of metformin on metabolic effect of insulin in human adipose tissue in vitro Diabete & metabolisme, 1984
- Characterization and evaluation of metformin-loaded solid lipid nanoparticles for celluar and mitochondrial uptake Drug development and industrial pharmacy, 2016
- Rutaecarpine enhances the anti-diabetic activity and hepatic distribution of metformin via up-regulation of Oct1 in diabetic rats Xenobiotica; the fate of foreign compounds in biological systems, 2021
- Starting titrating and intensifying metformin JPMA. The Journal of the Pakistan Medical Association, 2015
- Metformin extended release: metformin gastric retention, metformin GR, metformin XR. Drugs in R&D, 2005
- Lactic acidosis in metformin therapy Drugs, 1999
- Compounding Metformin for Use in Functional Medicine International journal of pharmaceutical compounding, 2023
- The effects of rabeprazole on metformin pharmacokinetics and pharmacodynamics in Chinese healthy volunteers Journal of pharmacological sciences, 2016
- Steady-state pharmacokinetics of a novel extended-release metformin formulation Clinical pharmacokinetics, 2005
- Metformin and cancer: Quo vadis et cui bono? Oncotarget, 2016
- The influence of Guar gum on absorption of metformin from the gut in healthy volunteers Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989
- OCT1-Mediated Metformin Uptake Regulates Pancreatic Stellate Cell Activity Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018
- Metformin accumulation without hyperlactataemia and metformin-induced hyperlactataemia without metformin accumulation Diabetes & metabolism, 2014
- Metformin versus metformin plus rosiglitazone in women with polycystic ovary syndrome Chinese medical journal, 2011
- Metformin - For the dermatologist Indian journal of pharmacology, 2016
- Reduction of metformin renal tubular secretion by cimetidine in man British journal of clinical pharmacology, 1987
- Metformin: New Preparations and Nonglycemic Benefits Current diabetes reports, 2017
- Continuous glucose monitoring in glimipiride plus metformin treated type 2 diabetic patients during the month of Ramadan La Tunisie medicale, 2012
- Value of combined subcutaneous infusion of insulin and metformin in 10 insulin-dependent obese diabetics Diabete & metabolisme, 1987
- Metformin inhibits follicle-stimulating hormone (FSH) action in human granulosa cells: relevance to polycystic ovary syndrome The Journal of clinical endocrinology and metabolism, 2013
- Continuing or stopping metformin in patients with type 2 diabetes exposed to SARS-CoV-2 ? Revue medicale de Liege, 2021
- Preventing Lethal Prostate Cancer with Diet, Supplements, and Rx: Heart Healthy Continues to Be Prostate Healthy and "First Do No Harm" Part III. Current urology reports, 2020
- Preventing Lethal Prostate Cancer with Diet, Supplements, and Rx: Heart Healthy Continues to Be Prostate Healthy and "First Do No Harm" Part I. Current urology reports, 2018
- Severe lactic acidosis due to metformin: report of 3 cases Annales de biologie clinique, 2011
- New promises for metformin: advances in the understanding of its mechanisms of action Medecine sciences : M/S, 2014
- Metformin and ageing: can treatment delay age-related diseases? Nederlands tijdschrift voor geneeskunde, 2021
- Subchronic metformin pretreatment enhances novel object recognition memory task in forebrain ischemia: behavioural, molecular, and electrophysiological studies Canadian journal of physiology and pharmacology, 2017
- Reactive-dystrophic processes in salivary glands (sialoadenoses) running on the background of metabolic syndrome Stomatologiia, 2011
- Effect of a nonsystemic, orally administered hydrogel, GS100, on metformin pharmacokinetics Canadian journal of physiology and pharmacology, 2018
- Potential protective associations of antidiabetic and lipid-lowering therapies with retinal vein occlusion risk: a systematic review and meta-analysis Eye (London, England), 2026
- Dysosmobacter: from a serendipitous discovery to a next-generation beneficial gut commensal linked to health eGastroenterology, 2026
- Molecular insights into GLP-1 receptor agonists and emerging metabolic-inflammatory targets in hidradenitis suppurativa Expert opinion on therapeutic targets, 2026
- Berberine induces pleiotropic beneficial effects via hormesis Pharmacological research, 2026
- AMPK-Directed Therapeutics for MASLD: Mechanistic Rationale, Activator Classes, and Clinical Translation International journal of molecular sciences, 2026
- Evaluating the Therapeutic Potential of Antioxidants in Polyendocrine Metabolic Ovarian Syndrome (PMOS)-Associated Infertility International journal of women's health, 2026
- Pancreatogenic Diabetes Mellitus - Type 3c (T3cDM) Journal of gastrointestinal and liver diseases : JGLD, 2026
- Exploiting Metabolic Vulnerabilities in Acute Myeloid Leukemia: Rationale and Evidence for Combining Metabolic Modulators with Conventional Chemotherapy Pharmaceuticals (Basel, Switzerland), 2026
- Overview of metformin: special focus on metformin extended release Expert opinion on pharmacotherapy, 2012
- Cardioprotection by Metformin: Beneficial Effects Beyond Glucose Reduction American journal of cardiovascular drugs : drugs, devices, and other interventions, 2018
- Metformin-'BRAINS & AIMS' pharmacological/prescribing principles of commonly prescribed (Top 100) drugs: Education and discussion British journal of clinical pharmacology, 2023
- Metabolic roles of AMPK and metformin in cancer cells Molecules and cells, 2013
- Metformin and insulin: is there a role for combination therapy? The Annals of pharmacotherapy, 1997
- Role of AMP-activated protein kinase in renal ischemic preconditioning Nephrologie & therapeutique, 2014
- Metformin in Alzheimer's disease: An overview of potential mechanisms, preclinical and clinical findings Biochemical pharmacology, 2022
- Potential role for metformin in urologic oncology Investigative and clinical urology, 2016
- Metformin and polycystic ovary syndrome Current opinion in endocrinology, diabetes, and obesity, 2007
- Metformin is not just an antihyperglycaemic drug but also has protective effects on the vascular endothelium Acta physiologica (Oxford, England), 2017