Browse studies, page 1157

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Safety of Quinolones in Children: A Systematic Review and Meta-Analysis Paediatric drugs, 2022
Fluoroquinolones in the management of tuberculous meningitis: Systematic review and meta-analysis The Journal of infection, 2018
A Meta-Analysis of Levofloxacin for Contacts of Multidrug-Resistant Tuberculosis NEJM evidence, 2025
Meta-analysis on Effectiveness and Safety of Moxifloxacin in Treatment of Multidrug Resistant Tuberculosis in Adults Medicine, 2020
A systematic review and meta-analysis of levofloxacin and ciprofloxacin in the treatment of urinary tract infection Annals of palliative medicine, 2021
Treatment of Helicobacter pylori Infection in Korea: A Systematic Review and Meta-analysis Journal of Korean medical science, 2015
Respiratory fluoroquinolone monotherapy versus β-lactam plus macrolide combination therapy for hospitalized adults with community-acquired pneumonia: A systematic review and meta-analysis of randomised controlled trials International journal of antimicrobial agents, 2023
Efficacy of Doxycycline for Mild-to-Moderate Community-Acquired Pneumonia in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023
Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis The lancet. Gastroenterology & hepatology, 2024
Identifying the Best Initial Oral Antibiotics for Adults with Community-Acquired Pneumonia: A Network Meta-Analysis Journal of general internal medicine, 2024
Global prevalence of Helicobacter pylori antibiotic resistance among children in the world health organization regions between 2000 and 2023: a systematic review and meta-analysis BMC medicine, 2024
Global Primary Antibiotic Resistance Rate of Helicobacter pylori in Recent 10 years: A Systematic Review and Meta-Analysis Helicobacter, 2024
Efficacy of treatment options for complicated urinary tract infections including acute pyelonephritis: a systematic literature review and network meta-analysis Journal of comparative effectiveness research, 2025
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis The Lancet. Respiratory medicine, 2020
Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions Gastroenterology, 2018
Mesoporous Silica Nanoparticles Decorated with Polycationic Dendrimers for Infection Treatment Acta Biomaterialia. 68, 261-271 (2018), 2021
Molecular gates in mesoporous bioactive glasses for the treatment of bone tumors and infection Acta Biomaterialia 50, 114-126 (2017), 2021
Impact of the antibiotic-cargo from MSNs on Gram-positive and Gram-negative bacterial biofilms Microporous and Mesoporous Materials 311 (2021), 110681, 2021
Multifunctional antibiotic- and zinc-containing mesoporous bioactive glass scaffolds to fight bone infection Acta Biomaterialia 114, 395-406 (2020), 2021
A Novel Semi-Supervised Algorithm for Rare Prescription Side Effect Discovery IEEE Journal of Biomedical and Health Informatics, 18 (2), pp. 537-547, 2014, 2014
Concanavalin A-targeted mesoporous silica nanoparticles for infection treatment Acta Biomaterialia. 96, 547-556 (2019), 2021
A versatile multicomponent mesoporous silica nanosystem with dual antimicrobial and osteogenic effects Acta Biomaterialia 136 (2021) 570 to 581, 2021
Effective reduction of biofilm through photothermal therapy by gold core@shell based mesoporous silica nanoparticles Microporous and Mesoporous Materials 328 (2021) 111489, 2021
3D scaffold with effective multidrug sequential release against bacteria biofilm Acta Biomaterialia. 49, 113-126 (2017), 2021
Multifunctional pH sensitive 3D scaffolds for treatment and prevention of bone infection Acta Biomaterialia. 65, 450-461 (2018), 2021
In vitro and in vivo activities of levofloxacin against biofilm-producing Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy, 1998
Inhibitors of Efflux Pumps in Pseudomonas a eruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin Journal of Medicinal Chemistry, 1999
Fluoroquinolone-resistant Streptococcus pneumoniae associated with levofloxacin therapy The Journal of Infectious Diseases, 2001
Azithromycin and levofloxacin use and increased risk of cardiac arrhythmia and death The Annals of Family Medicine, 2014
Outcomes of patients with multidrug-resistant pulmonary tuberculosis treated with ofloxacin/levofloxacin-containing regimens CHEST Journal, 2000
Effect of Levofloxacin Prophylaxis on Bacteremia in Children With Acute Leukemia or Undergoing Hematopoietic Stem Cell Transplantation: A Randomized Clinical Trial JAMA, 2018
Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection Antimicrobial Agents and Chemotherapy, 1999
Antimicrobial chemotherapy for Legionnaires disease: levofloxacin versus macrolides Clinical Infectious Diseases, 2005
Ceftolozane-tazobactam compared with levofloxacin in the treatment of complicated urinary-tract infections, including pyelonephritis: a randomised, double-blind, phase 3 trial (ASPECT-cUTI) The Lancet, 2015
Levofloxacin-Based Triple Therapy versus Bismuth-Based Quadruple Therapy for Persistent Helicobacter pylori Infection: A Meta-Analysis. CME The American Journal of Gastroenterology, 2006
Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis PubMed, 2006
Bacteremia Due to Viridans Group Streptococci with Diminished Susceptibility to Levofloxacin among Neutropenic Patients Receiving Levofloxacin Prophylaxis Clinical Infectious Diseases, 2002
Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses Antimicrobial Agents and Chemotherapy, 1997
Population pharmacokinetics of levofloxacin, gatifloxacin, and moxifloxacin in adults with pulmonary tuberculosis Antimicrobial Agents and Chemotherapy, 2007
Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: a case-control study Clinical Infectious Diseases, 2001
Pharmacodynamics of levofloxacin and ciprofloxacin against Streptococcus pneumoniae Journal of Antimicrobial Chemotherapy, 1999
A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia Antimicrobial Agents and Chemotherapy, 1997
Levofloxacin, a second-generation fluoroquinolone Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, 1998
In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin Antimicrobial Agents and Chemotherapy, 1992
Levofloxacin: a therapeutic review Clinical Therapeutics, 1998
Adsorption behavior of the antibiotic levofloxacin on microplastics in the presence of different heavy metals in an aqueous solution Chemosphere, 2020
Systematic review and meta-analysis: levofloxacin-based rescue regimens after Helicobacter pylori treatment failure Alimentary Pharmacology & Therapeutics, 2005
Levofloxacin. Its use in infections of the respiratory tract, skin, soft tissues and urinary tract Drugs, 1998
High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigm Clinical Infectious Diseases, 2003
Levofloxacin : a review of its use as a high-dose, short-course treatment for bacterial infection Drugs, 2008
Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4/NF-kB pathway Journal of Neuroinflammation, 2019
Resistance to Levofloxacin and Failure of Treatment of Pneumococcal Pneumonia New England Journal of Medicine, 2002
Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia New England Journal of Medicine, 2005
Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials JAMA, 1998
Randomized Controled Multicentric Trial, of Non Inferiority, Comparing Two Durations of Antibiotherapy (5 Days Versus 10 Days) in COMMUNAUTARY Acute Uncomplicated Pyelonephritis ClinicalTrials.gov · COMPLETED, 2011
A Randomized, Observer-masked, Parallel-group, Multicenter Trial Evaluating the Ocular Penetration of 1.5% Levofloxacin Ophthalmic Solution and 0.5% Moxifloxacin Ophthalmic Solution in Subjects Undergoing Corneal Transplant Surgery ClinicalTrials.gov · TERMINATED
A Phase 3, Randomized, Double-Blind, Double-Dummy, Multicenter, Prospective Study to Assess the Efficacy and Safety of IV Eravacycline Compared With Ertapenem in Complicated Urinary Tract Infections ClinicalTrials.gov · COMPLETED, 2018
Assessment of the Effects and Tolerability of RD03/2016 (Levofloxacin; Ketorolac Trometamol 0.5+0.5% w/v Eye Drops Solution) for the Treatment of Bacterial Conjunctivitis in Adults: a Multicentre, Randomized, Blinded-assessor, Phase II Non Inferiority Study - MIRAKLE ClinicalTrials.gov · COMPLETED, 2023
Comparing the Efficacy of 14-day Therapy Doxycycline With Bismuth Subsalicylate Versus Levofloxacin With Tinidazole on Rate of Eradication of Helicobacter Pylori Infected Patients on Syrian Population ClinicalTrials.gov · COMPLETED, 2020
A Single- Centre, Randomised Study Of The Clinical And Microbiological Efficacy Of Decreasing The Dosage Of Levofloxacin 0,5% Eye Drops As Compared To Standard Eye Drop Dosage In Patients With Bacterial Conjunctivitis ClinicalTrials.gov · COMPLETED, 2006
Efficacies of Two Bismuth Quadruple Therapies in the Second-line Treatment of H Pylori Infection - a Multi-center Randomized Controlled Trial ClinicalTrials.gov · COMPLETED, 2020
Phase I Clinical Trial, to Evaluate the Safety and Tolerability of the Ophthalmic Solution PRO-174 Versus Sophixín Ofteno®, Elaborated by Laboratorios Sophia on the Ocular Surface of Ophthalmological and Clinically Healthy Subjects ClinicalTrials.gov · COMPLETED, 2018
Prospective Randomized Study to Compare Clinical Outcomes in Patients With Osteomyelitis Treated With Intravenous Antibiotics Versus Intravenous Antibiotics With an Early Switch to Oral Antibiotics ClinicalTrials.gov · TERMINATED, 2018
Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection-A Randomized Clinical Trial ClinicalTrials.gov · COMPLETED, 2019
Aqueous Humour Concentrations After Topical apPlication of combinEd Levofloxacin-dexamethasone Eye dRops and of Its Single Components: a randoMized, assEssor-blinded, Parallel-group Study in Patients Undergoing Cataract Surgery - iPERME ClinicalTrials.gov · COMPLETED, 2018
A Phase II, Multi-Center, Randomized, Parallel Controlled Study to Evaluate the Clinical Efficacy and Safety of IVIEW 1201 Compared to Ofloxacin Eye Drops in the Treatment of Acute Bacterial Conjunctivitis ClinicalTrials.gov · COMPLETED, 2024
An Open-label, Randomized, 3-way Crossover Study to Evaluate the Bioequivalence of an Oral Suspension Formulation, an Oral Solution Formulation, and the Marketed Tablet Formulation of Levofloxacin in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2002
A Multicenter, Active-Controlled, Randomized Study to Evaluate the Safety and Efficacy of Oral Levofloxacin Versus Cefaclor in the Treatment of Acute Bacterial Exacerbation of Chronic Bronchitis in Adults ClinicalTrials.gov · COMPLETED, 1994
Phase 4 Study of Azitromicin in the Treatment of PID ClinicalTrials.gov · COMPLETED, 2010
Comparative Study of the Levofloxacin-Based and Clarithromycin-Based Triple Therapy in First-Line Treatment for Helicobacter Pylori Eradication and Change of Gut Flora and Drug Susceptibility Before and After Treatment ClinicalTrials.gov · COMPLETED, 2009
Evaluation of Two Strategies of Antibiotic Treatment With Levofloxacin in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Short Treatment-versus Treatment Guided by Markers of Inflammation ClinicalTrials.gov · COMPLETED, 2019
Assessment of Hematological Effect of H.Pylori and H.Pylori Eradication Therapy Among a Sample of Iraqi ITP Patients ClinicalTrials.gov · COMPLETED, 2025
A Randomized, Double-masked, Parallel Group Study of DE-108 Ophthalmic Solution in Patients Who Are Scheduled for Cataract Surgery (Levofloxacin 0.5% Ophthalmic Solution as a Comparator) - Phase III, Confirmatory Study of Perioperative Bacteria Eradication - ClinicalTrials.gov · COMPLETED, 2017
A Randomized, Double-Blind, Comparative, Multi-Center Study of the Safety and Efficacy of TG-873870(Nemonoxacin) Versus Levofloxacin in Adult Patients With Community-Acquired Pneumonia (CAP) ClinicalTrials.gov · COMPLETED, 2012
A Randomized, Prospective Double-Blind, Placebo-Controlled Trial of Prophylactic Oral Levofloxacin Following Chemotherapy for Lymphoma and Solid Tumors ClinicalTrials.gov · COMPLETED, 2005
An Open-label, Multi-center, Non-comparative Sinus Puncture Study of 750 mg, Short-course Levofloxacin in the Treatment of Acute Maxillary Sinusitis ClinicalTrials.gov · COMPLETED, 2005
TREATMENT OF ACUTE UNCOMPLICATED PYELONEPHRITIS WITH SHORT COURSE LEVOFLOXACIN A Pilot Study ClinicalTrials.gov · TERMINATED, 2005
A Phase 3, Randomized, Multicenter, Double-Blind Study to Evaluate the Efficacy and Safety of Plazomicin Compared With Meropenem Followed by Optional Oral Therapy for the Treatment of Complicated Urinary Tract Infection (cUTI), Including Acute Pyelonephritis (AP), in Adults ClinicalTrials.gov · COMPLETED, 2016
An Open-Label Study of Levofloxacin to Evaluate Bacteriologic Outcome in the Treatment of Children Who Are at Risk for Acute Otitis Media That is Difficult to Treat ClinicalTrials.gov · COMPLETED, 2003
The Clinical Trial of Methylene Blue Application Combined With Photodynamic Therapy for Treatment of SARS-CoV-2 Infected Patients ClinicalTrials.gov · COMPLETED, 2020
Personalized Treatment for Refractory H Pylori Infection ClinicalTrials.gov · COMPLETED, 2021
A Multicenter, Double-Blind, Randomized Study To Compare The Safety And Efficacy Of Oral Levofloxacin With That Of Ciprofloxacin HCl In The Treatment Of Complicated Urinary Tract Infections In Adults ClinicalTrials.gov · COMPLETED, 1995
Swiss PACK-CXL (Photoactivated Chromophore for Infectious Keratitis Cross-linking) Multicenter Trial for the Treatment of Infectious Keratitis ClinicalTrials.gov · COMPLETED, 2020
Evaluation of Corneal Hysteresis and Corneal Resistance Factor After Corneal Cross-linking for Keratoconus ClinicalTrials.gov · COMPLETED, 2010
Phase I, Single and Multi-dose, Placebo Controlled, Randomized, Dose-Escalation Study to Evaluate the Safety, Tolerability and PK Profile of MP-376 Using the PARI eFlow Nebulizer for 14 Days to CF Patients ClinicalTrials.gov · COMPLETED, 2007
Antibiotic Treatment for 7 Days Versus 14 Days in Patients With Acute Male Urinary Tract Infection Due to Fluoroquinolones Susceptible Bacteria: a Multicentre, Non-inferiority, Double Blind, Randomized Placebo-controlled Trial ClinicalTrials.gov · COMPLETED, 2019
A Double-blind, Randomized Controlled Pilot Study Comparing the Safety and Efficacy of Intracameral Levofloxacin and Intracameral Cefazolin in Cataract Surgery ClinicalTrials.gov · COMPLETED, 2024
Phase I/II Randomized, Open-label Trial to Evaluate the PK, Safety, and Outcomes of Treatment Including High Dose Rifampicin +/- Levofloxacin vs Standard Treatment for Pediatric Tuberculous Meningitis (TBM) ClinicalTrials.gov · COMPLETED, 2020
Refining Multidrug Tuberculosis Treatment with the Ultra Short All Oral Regimen ClinicalTrials.gov · COMPLETED, 2024
A Multi-center, Randomized, Double-Blind, Parallel Comparative, Phase III Study to Evaluate the Efficacy and Safety of Intravenous Infusion of Nemonoxacin Versus Levofloxain in Treating Adult Patients With CAP ClinicalTrials.gov · COMPLETED, 2017
A Phase IV Comparative Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis ClinicalTrials.gov · COMPLETED
Comparative Controlled Trial of Treatment of Minor Unexpected Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy Screening in Women Indicated for IVF ClinicalTrials.gov · TERMINATED, 2009
Bioequivalence Study of Levomerc (Levofloxacin) 500 mg Tablet With Tavanic (Levofloxacin) 500 mg Tablets ClinicalTrials.gov · COMPLETED, 2012
Antibiotyping and Prevalence of Virulent Genotypes Among Helicobacter Pylori and Their Impact on Response to Therapy ClinicalTrials.gov · COMPLETED, 2025
Population Pharmacokinetics of Levofloxacin in Intensive Care Patients With Severe Community-acquired Pneumonia ClinicalTrials.gov · COMPLETED, 2014
A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms ClinicalTrials.gov · COMPLETED, 2013
An Open-Label Randomized Multiple-Dose Study to Evaluate Levofloxacin Steady-State Pharmacokinetics and Safety in Subjects With Varying Degrees of Renal Function ClinicalTrials.gov · COMPLETED, 2006
A Phase 3, Randomized, Double-blind, Double-dummy, Multicenter, Prospective Study to Assess the Efficacy and Safety of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections ClinicalTrials.gov · COMPLETED, 2015
A Prospective Randomized Trial of Levofloxacin-amoxicillin Triple Therapy vs. Levofloxacin-tetracycline Quadruple Therapy in Second-line Helicobacter Pylori Treatment ClinicalTrials.gov · COMPLETED, 2017
A Randomized Control Trial Of High-Dose Isoniazid Adjuvant Therapy For Multidrug Resistant Tuberculosis ClinicalTrials.gov · COMPLETED, 2006