Browse studies, page 1220
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- Targeting the Intestinal Microbiota to Prevent Type 2 Diabetes and Enhance the Effect of Metformin on Glycaemia: A Randomised Controlled Pilot Study Nutrients, 2020
- Metformin and energy metabolism in breast cancer: from insulin physiology to tumour-initiating stem cells Current molecular medicine, 2010
- Metformin-induced oxidative stress inhibits LNCaP prostate cancer cell survival Molecular biology reports, 2024
- Cardiovascular Safety and Benefits of Noninsulin Antihyperglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus-Part 1 Cardiology in review, 2020
- The efficacy of metformin in counteracting olanzapine-induced hyperprolactinemia: an open-label prospective study International journal of psychiatry in clinical practice, 2025
- Metformin and Myocardial Injury in Patients With Diabetes and ST-Segment Elevation Myocardial Infarction: A Propensity Score Matched Analysis Journal of the American Heart Association, 2015
- The Effect of Metformin on Survival Outcomes of Non-Metastatic Breast Cancer Patients with Type 2 Diabetes Asian Pacific journal of cancer prevention : APJCP, 2021
- Dose-dependent relation between metformin and the risk of hormone receptor-positive, her2-negative breast cancer among postmenopausal women with type-2 diabetes Breast cancer research and treatment, 2022
- Mechanisms of metformin's anti‑tumor activity against gemcitabine‑resistant pancreatic adenocarcinoma International journal of oncology, 2019
- Human periodontal ligament stem cells and metformin to enhance periodontal regeneration in rats Journal of dentistry, 2025
- MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway Scientific reports, 2017
- Proangiogenic Effect of Metformin in Endothelial Cells Is via Upregulation of VEGFR1/2 and Their Signaling under Hyperglycemia-Hypoxia International journal of molecular sciences, 2018
- Metformin and carotid intima-media thickness in never-smokers with type 1 diabetes: The REMOVAL trial Diabetes, obesity & metabolism, 2021
- Enhancement of Metformin's Efficacy by Betel Nut Polyphenols in Type 2 Diabetic Rats Exposed to High Altitude Endocrine, metabolic & immune disorders drug targets, 2026
- Impact of immediate-release versus extended-release metformin on lipid profile and body measurements in Saudi patients with type 2 diabetes: a prospective cohort study The Pan African medical journal, 2025
- Metformin's protection against blood-brain barrier disruption and neuronal dysfunction under oxygen-glucose deprivation and tobacco smoke and e-vape chemical exposure Fluids and barriers of the CNS, 2025
- Deciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin Action PLoS computational biology, 2015
- Action of metformin on glucose transport and glucose transporter GLUT1 and GLUT4 in heart muscle cells from healthy and diabetic rats Endocrinology, 1995
- Metformin and exercise effects on postprandial insulin sensitivity and glucose kinetics in pre-diabetic and diabetic adults American journal of physiology. Endocrinology and metabolism, 2023
- Metformin's effects beyond ischemia: Evaluating cardioprotection in nonischemic myocardium in a large animal model of coronary and metabolic disease The Journal of thoracic and cardiovascular surgery, 2026
- New Insight Into Metformin Action: Regulation of ChREBP and FOXO1 Activities in Endothelial Cells Molecular endocrinology (Baltimore, Md.), 2015
- Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer Aging, 2011
- Metformin Protects Against Noise-Induced Hearing Loss in Male Mice Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2023
- Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma Clinical cancer research : an official journal of the American Association for Cancer Research, 2013
- Effect of metformin on hypoxia-associated gene expression in oral cavity squamous cell carcinoma in non-diabetic patients - a prospective window of opportunity study European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025
- Applying a hypothetical strategy to the intercurrent event of non-adherence with the parametric g-formula: a post hoc secondary analysis of the MET-PREVENT randomised controlled trial Trials, 2026
- Metformin inhibits IgE- and aryl hydrocarbon receptor-mediated mast cell activation in vitro and in vivo European journal of immunology, 2018
- Combination therapy of systemic and local metformin improves imiquimod-induced psoriasis-like lesions with type 2 diabetes: the role of AMPK/KGF/STAT3 axis Archives of physiology and biochemistry, 2025
- The Effect of Metformin on Vestibular Schwannoma Growth: A Systematic Review and Meta-analysis The Laryngoscope, 2023
- PCK1 and SLC22A2 gene variants associated with response to metformin treatment in type 2 diabetes PloS one, 2025
- Lactic acidosis induced by excessive ingestion of metformin European journal of toxicology and environmental hygiene. Journal europeen de toxicologie, 1976
- Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo Nature medicine, 2018
- Elucidating metformin action on the ovary and fertility in healthy mice Reproduction (Cambridge, England), 2024
- Tangeretin boosts the anticancer activity of metformin in breast cancer cells via curbing the energy production Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021
- Transcriptomic landscape profiling of metformin-treated healthy mice: Implication for potential hypertension risk when prophylactically used Journal of cellular and molecular medicine, 2020
- Utility of support vector machine and decision tree to identify the prognosis of metformin poisoning in the United States: analysis of National Poisoning Data System BMC pharmacology & toxicology, 2022
- Implantable Drug Reservoir Devices for Inner Ear Delivery of Pharmacotherapeutics Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2020
- The Potential Therapeutic Impact of Metformin in Glioblastoma Multiforme Current medicinal chemistry, 2023
- The Molecular Mechanisms of Metformin's Action on Blood Lipid Profile in Diabetic Patients International journal of molecular sciences, 2026
- Metformin-induced RBMS3 expression enhances ferroptosis and suppresses ovarian cancer progression Reproductive biology, 2025
- Metformin use in prediabetes: A review of evidence and a focus on metabolic features among peri-menopausal women Diabetes, obesity & metabolism, 2025
- Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity Journal of medical virology, 2021
- Repurposing Metformin in Precision Oncology: Mechanistic Insights, Biomarker-Guided Strategies, and Translational Imperatives Medicina (Kaunas, Lithuania), 2025
- Evaluation for clinical benefit of metformin in patients with idiopathic pulmonary fibrosis and type 2 diabetes mellitus: a national claims-based cohort analysis Respiratory research, 2022
- Regulation of metformin response by breast cancer associated gene 2 Neoplasia (New York, N.Y.), 2013
- Metformin Suppress Th17 Differentiation and Function to Improve Glandular Function in Primary Sjögren's Syndrome International journal of rheumatic diseases, 2026
- Metformin inhibits HaCaT cell viability via the miR-21/PTEN/Akt signaling pathway Molecular medicine reports, 2018
- Metformin for endothelial dysfunction in non-diabetic disorders: a scoping review BMJ open, 2025
- Modulation of the Antitumor Response to Metformin, Caffeine, and Sodium Dichloroacetate by the Hypoxic Microenvironment in Lung Cancer Cells International journal of molecular sciences, 2025
- Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation Journal of experimental & clinical cancer research : CR, 2019
- Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin Molecular pharmacology, 2015
- Review of Interventions for the Frailty Syndrome and the Role of Metformin as a Potential Pharmacologic Agent for Frailty Prevention Clinical therapeutics, 2019
- Novel mechanistic insights of the potential role of gasotransmitters and autophagy in the protective effect of metformin against hepatic ischemia/reperfusion injury in rats Naunyn-Schmiedeberg's archives of pharmacology, 2025
- Protocol for a Randomized Phase II/III Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Extended-Release Metformin in Amnestic Mild Cognitive Impairment: Metformin in Alzheimer Dementia Prevention (MAP) Alzheimer disease and associated disorders, 2025
- Emerging strategies in drug repurposing for decreasing the risk of age-related macular degeneration Expert opinion on drug discovery, 2026
- Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study International journal of molecular sciences, 2023
- Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms PloS one, 2025
- Effects of metformin on wild fathead minnows (Pimephales promelas) using in-lake mesocosms in a boreal lake ecosystem The Science of the total environment, 2024
- Metformin pre-treatment of stem cells from human exfoliated deciduous teeth promotes migration and angiogenesis of human umbilical vein endothelial cells for tissue engineering Cytotherapy, 2022
- Metformin Inhibits Cell Motility and Proliferation of Triple-Negative Breast Cancer Cells by Blocking HMGB1/RAGE Signaling Cells, 2025
- Metformin's Role in Hyperlactatemia and Lactic Acidosis in ICU Patients: A Systematic Review Pharmacology, 2023
- Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells Journal of experimental & clinical cancer research : CR, 2025
- Vitamin D potentiation of metformin hepatoprotective activities: Concurrent targeting of carbohydrate enzymatic pathways and PCSK9/AGEs-regulated oxidative stress mechanisms in type 2 diabetic male Wistar rats Steroids, 2025
- Rationale and protocol of the MetNET-1 trial, a prospective, single center, phase II study to evaluate the activity and safety of everolimus in combination with octreotide LAR and metformin in patients with advanced pancreatic neuroendocrine tumors Tumori, 2014
- Metformin improves skeletal muscle microvascular insulin resistance in metabolic syndrome American journal of physiology. Endocrinology and metabolism, 2022
- Reports of Lactic Acidosis Attributed to Metformin, 2015-2018 Diabetes care, 2020
- Targeting of the diabetes prevention program leads to substantial benefits when capacity is constrained Acta diabetologica, 2021
- Diabetes, metformin use, and colorectal cancer survival in postmenopausal women Cancer epidemiology, 2013
- High Throughput Study for Molecular Mechanism of Metformin Pre-Diabetic Protection via Microarray Approach Endocrine, metabolic & immune disorders drug targets, 2022
- Gut microbiota-derived UDCA enhanced by metformin inhibits FXR to activate autophagy against MCD diet-induced NAFLD in mice International immunopharmacology, 2025
- Differing effects of metformin on glycemic control by race-ethnicity The Journal of clinical endocrinology and metabolism, 2014
- Metformin in vitro and in vivo increases adenosine signaling in rabbit corpora cavernosa The journal of sexual medicine, 2014
- Sargassum polycystum reduces hyperglycaemia, dyslipidaemia and oxidative stress via increasing insulin sensitivity in a rat model of type 2 diabetes Journal of the science of food and agriculture, 2013
- Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts PloS one, 2013
- Association between metformin use and mortality in patients with type 2 diabetes mellitus and localized resectable pancreatic cancer: a nationwide population-based study in korea Oncotarget, 2017
- Metformin modifies disparity in hepatocellular carcinoma incidence in men with type 2 diabetes but without chronic liver diseases Cancer medicine, 2019
- Prenatal metformin exposure or organic cation transporter 3 knock-out curbs social interaction preference in male mice Pharmacological research, 2019
- Interaction between Metformin, Folate and Vitamin B12 and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies International journal of molecular sciences, 2021
- Metformin monotherapy versus predominantly older non-metformin antidiabetic medications for cerebrovascular risk in early type 2 diabetes management Diabetes, obesity & metabolism, 2024
- Identification of patient characteristics associated with survival benefit from metformin treatment in patients with stage I non-small cell lung cancer The Journal of thoracic and cardiovascular surgery, 2022
- Glucose availability but not changes in pancreatic hormones sensitizes hepatic AMPK activity during nutritional transition in rodents arXiv, 2020
- Data-Driven Allocation of Preventive Care With Application to Diabetes Mellitus Type II arXiv, 2023
- Development and optimization of low power non-thermal plasma jet operational parameters for treating dyes and emerging contaminants arXiv, 2022
- Increased hepatic PDGF-AA signaling mediates liver insulin resistance in obesity associated type 2 diabetes arXiv, 2017
- Extra-Low-Frequency Magnetic Fields alter Cancer Cells through Metabolic Restriction arXiv, 2012
- Determination of personalized diabetes treatment plans using a two-delay model arXiv, 2014
- Thesis: The Effects of Hypoxia, Metabolic Restriction and Magnetic Fields on Chromosome Instability and Karyotype Contraction in Cancer Cell Lines arXiv, 2014
- Structural mean models for instrumented difference-in-differences arXiv, 2022
- Gene set proximity analysis: expanding gene set enrichment analysis through learned geometric embeddings arXiv, 2022
- Bayesian Benefit-Risk Assessment with Dependent Outcomes via Latent Factor Models arXiv, 2022
- Selection bias when using instrumental variable methods to compare two treatments but more than two treatments are available arXiv, 2015
- A series acceleration algorithm for the gamma-Pareto (type I) convolution and related functions of interest for pharmacokinetics arXiv, 2021
- Entitymetrics: Measuring the Impact of Entities PLOS ONE 8(8): e71416, 2013, 2013
- Considerations of automated machine learning in clinical metabolic profiling: Altered homocysteine plasma concentration associated with metformin exposure Pacific Symposium on Biocomputing, 2018 (Vol. 23), 2017
- Unique Features of Metformin: A Combined Experimental, Theoretical, and Simulation Study of Its Structure, Dynamics, and Interaction Energetics with DNA Grooves arXiv, 2018
- Electroporation-mediated Metformin for effective anticancer treatment of triple-negative breast cancer cells arXiv, 2024
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1 Cancer Research, 2011
- Metformin Use and Mortality Among Patients With Diabetes and Atherothrombosis Metformin Use With Diabetes and Atherothrombosis Archives of Internal Medicine, 2010
- Understanding the benefit of metformin use in cancer treatment BMC Medicine, 2011
- Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes Diabetes Care, 2009
