Browse studies, page 548

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• A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Proof-of-Concept Study to Evaluate the Efficacy of Maximally Tolerated Doses of Retigabine vs. Placebo in Reducing the Pain Associated With Post-Herpetic Neuralgia ClinicalTrials.gov · COMPLETED, 2009
• Developing and Pilot Testing an Intervention to Increase Opioid Tapering in Primary Care ClinicalTrials.gov · COMPLETED, 2023
• A Phase 2, Randomized, Double-Blind, Placebo- and Comparator-Controlled Trial to Evaluate the Safety and Efficacy of Combination of Pregabalin and Acetaminophen Compared to Acetaminophen and Placebo in Subjects Undergoing Bunionectomy ClinicalTrials.gov · COMPLETED, 2020
• Comparative Evaluation of the Effectiveness of Diclofenac Sodium Versus Vitamin D Supplements on Symptoms in Individuals With Myofascial Pain and Vitamin D Deficiency ClinicalTrials.gov · COMPLETED, 2023
• Randomized Clinical Trial Comparing the Use of Perioperative Epidural Analgesia to Conventional Intravenous Narcotics and NSAIDS for Patients Undergoing Laparoscopic Colorectal Resection ClinicalTrials.gov · COMPLETED, 2015
• A Dose-Finding Study to Assess the Safety, Tolerability, and Immunogenicity of Inactivated Streptococcus Pneumoniae Whole Cell Vaccine Formulated With Alum (PATH-wSP) in Healthy Kenyan Young Adults and PCV-Primed Toddlers ClinicalTrials.gov · COMPLETED, 2015
• Clinical Evaluation Of The Effects Of Propolis Gargle On Wound Healing After Impacted Third Molar Surgery ClinicalTrials.gov · COMPLETED, 2022
• Open-Label Extended Administration of SCH 54031 (PEG Interferon Alfa-2b/PEG Intron) in Subjects With Solid Tumors ClinicalTrials.gov · COMPLETED, 2001
• Auricular Acupuncture as Effective Pain Relief After Episiotomy: A Prospective Interventional Randomized Parallel Single-center Study ClinicalTrials.gov · COMPLETED, 2017
• The Efficacy of Pentoxifylline in Reducing Post-surgical Complications in Patients Undergoing Breast Cancer Surgery ClinicalTrials.gov · COMPLETED, 2024
• Enhanced Recovery After Spine Surgery (ERASS) Versus Traditional Spine Surgical Care (TC): A Randomized, Prospective Trial ClinicalTrials.gov · COMPLETED, 2021
• Oral Pregabalin Versus Intravenous Hydrocortisone in Treatment of Postdural Puncture Headache After Spinal Anesthesia for Elective Cesarean Section ClinicalTrials.gov · COMPLETED, 2019
• Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analysis of Intraindividual Variation in Healthy Adults ClinicalTrials.gov · COMPLETED, 2018
• Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block vs Laparoscopic Intraperitoneal Instillation of Local Anesthetic in Pediatrics Undergoing Inguinal Hernia Repair: A Randomized Controlled Trial ClinicalTrials.gov · COMPLETED, 2024
• Study of Automated Lamellar Keratectomy With a New Option in Treatment in Symptomatic Patients With Bullous Keratopathy ClinicalTrials.gov · COMPLETED, 2008
• Effect of Number of Meals on Metabolism After Weight Loss Surgery ClinicalTrials.gov · COMPLETED, 2014
• Gastric Ultrasound To Assess Gastric Contents In Patients On Semaglutide Therapy ClinicalTrials.gov · COMPLETED, 2025
• Nitrous Oxide for Pain Management During In-office Transcervical Sterilization ClinicalTrials.gov · COMPLETED, 2015
• Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery: A Prospective, Randomized Double Blinded Study ClinicalTrials.gov · COMPLETED, 2023
• Effect of Early Warm Water Sitz Bath on Urinary Retention After Hemorrhoidectomy ClinicalTrials.gov · COMPLETED, 2020
• MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2014
• Does Addition of Longer-acting Local Anesthetic Improve the Post-operative Pain After Carpal Tunnel Release? A Randomized Controlled Study ClinicalTrials.gov · COMPLETED, 2022
• The Efficacy of Intravenous Paracetamol Versus Dipyrone for Postoperative Analgesia After Day-case Lower Abdominal Surgery in Children With Spinal Anesthesia: a Prospective Randomized Double-blind Study ClinicalTrials.gov · COMPLETED, 2011
• Brain Mechanisms of Acupuncture Treatment in Chronic Low Back Pain ClinicalTrials.gov · COMPLETED, 2017
• Opioid-Free Shoulder Arthroplasty ClinicalTrials.gov · COMPLETED, 2019
• Pre vs. Postoperative Adductor Canal Block for Total Knee Arthroplasty: Prospective Randomized Trial ClinicalTrials.gov · COMPLETED, 2024
• Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment ClinicalTrials.gov · COMPLETED, 2020
• Efficacy of Multimodal Analgesia Following Hip Arthroscopy ClinicalTrials.gov · COMPLETED, 2021
• Effect of Paracetamol Versus Paracetamol Combined With Pregabalin Versus Paracetamol Combined With Pregabalin and Dexamethasone on Pain and Opioid Requirements in Patients Scheduled for Abdominal Hysterectomy ClinicalTrials.gov · COMPLETED, 2008
• Plantar Compartment Block Versus Sciatic Block in Hallux Valgus Ambulatory Surgery : a Prospective, Randomised, Double Blind Study ClinicalTrials.gov · COMPLETED, 2022
• Are Opioids Needed: A Double-Blinded, Randomized Controlled Trial and Examination of Predictors of Opioid Use Following ACL Reconstruction ClinicalTrials.gov · COMPLETED, 2022
• A Randomized, 2-Way, Parallel, Single-Blind Pharmacokinetic Study to Evaluate the Interaction Between Intravenous Morphine and Orally or Intravenously Administered Acetaminophen in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2016
• Evaluation of an Orally Administered Medication When Taken in Conjunction With Pramlintide ClinicalTrials.gov · COMPLETED, 2002
• A Randomized, Double-Blind, Multicenter Study Evaluating The Safety and Efficacy of BTDS in Subjects With Moderate to Severe Osteoarthritis Pain. Includes a 52-Week Extension Phase ClinicalTrials.gov · TERMINATED, 2005
• Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants Human Reproduction, 2016
• First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid Journal of Pain Research, 2017
• Pharmacokinetics of Oral and Intravenous Paracetamol (Acetaminophen) When Co-Administered with Intravenous Morphine in Healthy Adult Subjects Clinical drug investigation, 2017
• Anxiety‐ and activity‐related effects of paracetamol on healthy and neuropathic rats Pharmacology Research & Perspectives, 2017
• Prenatal paracetamol use and asthma in childhood: A systematic review and meta-analysis Allergologia et Immunopathologia, 2017
• Paracetamol: not as safe as we thought? A systematic literature review of observational studies Annals of the Rheumatic Diseases, 2015
• Toxicological effects of paracetamol on the clam Ruditapes philippinarum: exposure vs recovery Aquatic Toxicology, 2017
• Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD Clinical Epigenetics, 2017
• Acute and chronic effects of paracetamol exposure on Daphnia magna: how oxidative effects may modulate responses at distinct levels of organization in a model species Environmental science and pollution research international, 2018
• Paracetamol in Older People: Towards Evidence-Based Dosing? Drugs & Aging, 2018
• Paracetamol for low back pain Cochrane Database of Systematic Reviews, 2016
• Degradation of Paracetamol and Its Oxidation Products in Surface Water by Electrochemical Oxidation Hazardous Waste, 2018
• Putative Role of Flavobacterium, Dokdonella and Methylophilus Strains in Paracetamol Biodegradation Water, Air and Soil Pollution, 2018
• Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials British medical journal, 2015
• Oral paracetamol (acetaminophen) for cancer pain Cochrane Database of Systematic Reviews, 2017
• A clinical and safety review of paracetamol and ibuprofen in children InflammoPharmacology, 2017
• Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature European Journal of Clinical Pharmacology, 2017
• Influences of nitrite on paracetamol degradation in dielectric barrier discharge reactor Ecotoxicology and Environmental Safety, 2019
• Paracetamol for pain in adults British medical journal, 2019
• Redox Control of Antioxidant and Antihepatotoxic Activities of Cassia surattensis Seed Extract against Paracetamol Intoxication in Mice: In Vitro and In Vivo Studies of Herbal Green Antioxidant Oxidative Medicine and Cellular Longevity, 2016
• Efficacy and safety of oral paracetamol versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants: a randomized controlled trial Journal of Maternal-Fetal & Neonatal Medicine, 2019
• Fast-dissolving electrospun nanofibrous films of paracetamol/cyclodextrin inclusion complexes Applications of Surface Science, 2019
• Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies The Lancet Gastroenterology and Hepatology, 2017
• Hepatotoxicity of paracetamol and related fatalities European Review for Medical and Pharmacological Sciences, 2017
• Paracetamol - toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring degradation pathway Chemosphere, 2018
• Comparison of the paracetamol electrochemical determination using boron-doped diamond electrode and boron-doped carbon nanowalls Biosensors & bioelectronics, 2019
• Design of Controlled Release System for Paracetamol Based on Modified Lignin Polymers, 2019
• Safety of Paracetamol in Osteoarthritis: What Does the Literature Say? Drugs & Aging, 2019
• Fabrication of SnS/TiO2@GO Composite Coated Glassy Carbon Electrode for Concomitant Determination of Paracetamol, Tryptophan, and Caffeine in Pharmaceutical Formulations Analytical Chemistry, 2019
• Taste masking of paracetamol encapsulated in chitosan-coated alginate beads Journal of Drug Delivery Science and Technology, 2020
• Intravenous paracetamol in comparison with ibuprofen for the treatment of patent ductus arteriosus in preterm infants: a randomized controlled trial European Journal of Pediatrics, 2020
• Effect of Solution pH on the Adsorption of Paracetamol on Chemically Modified Activated Carbons Molecules, 2017
• Electrochemical detection of paracetamol and dopamine molecules using nano-particles of cobalt ferrite and manganese ferrite modified with graphite Heliyon, 2019
• 3D extrusion printing of high drug loading immediate release paracetamol tablets International journal of pharmaceutics, 2018
• Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples Journal of Pharmaceutical Analysis, 2020
• Enzyme-MOF Nanoreactor Activates Nontoxic Paracetamol for Cancer Therapy Angewandte Chemie, 2018
• Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand Medical Journal of Australia, 2019
• Long‐term adverse effects of paracetamol – a review British Journal of Clinical Pharmacology, 2018
• Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKβ/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation Antioxidants, 2021
• Protective role of Chlorella vulgaris with Thiamine against Paracetamol induced toxic effects on haematological, biochemical, oxidative stress parameters and histopathological changes in Wistar rats Scientific Reports, 2021
• Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial Journal of the American Medical Association (JAMA), 2019
• Organic micropollutants paracetamol and ibuprofen—toxicity, biodegradation, and genetic background of their utilization by bacteria Environmental science and pollution research international, 2018
• Removal of paracetamol from aqueous solution by activated carbon and silica. Experimental and computational study Journal of Contaminant Hydrology, 2020
• Determination of paracetamol using a sensor based on green synthesis of silver nanoparticles in plant extract Journal of Pharmaceutical and Biomedical Analysis, 2021
• The efficacy and safety of paracetamol for pain relief: an overview of systematic reviews Medical Journal of Australia, 2021
• Effects of nerol on paracetamol-induced liver damage in Wistar albino rats Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
• Evaluation of CNT-COOH/MnO2/Fe3O4 nanocomposite for ibuprofen and paracetamol removal from aqueous solutions Journal of Hazardous Materials, 2020
• Liver injury induced by paracetamol and challenges associated with intentional and unintentional use World Journal of Hepatology, 2020
• Egyptian perspectives on potential risk of paracetamol/acetaminophen-induced toxicities: Lessons learnt during COVID-19 pandemic Toxicology Reports, 2022
• Paracetamol – An old drug with new mechanisms of action Clinical and Experimental Pharmacology and Physiology, 2020
• Supercritical carbon dioxide utilization in drug delivery:Experimental study and modeling of paracetamol solubility European Journal of Pharmaceutical Sciences, 2022
• Why paracetamol (acetaminophen) is a suitable first choice for treating mild to moderate acute pain in adults with liver, kidney or cardiovascular disease, gastrointestinal disorders, asthma, or who are older Current Medical Research and Opinion, 2022
• Microbial paracetamol degradation involves a high diversity of novel amidase enzyme candidates bioRxiv, 2022
• Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action Temperature, 2021
• Paracetamol use during pregnancy — a call for precautionary action Nature Reviews Endocrinology, 2021
• On-Site Therapeutic Drug Monitoring of Paracetamol Analgesic in Non-Invasively Collected Saliva for Personalized Medicine Small, 2023
• Efficient adsorptive removal of paracetamol and thiazolyl blue from polluted water onto biosynthesized copper oxide nanoparticles Scientific Reports, 2023
• An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact Journal of Pain Research, 2023
• Comparative efficacy of exercise therapy and oral non-steroidal anti-inflammatory drugs and paracetamol for knee or hip osteoarthritis: a network meta-analysis of randomised controlled trials British Journal of Sports Medicine, 2023
• Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease Expert Opinion on Drug Metabolism & Toxicology, 2023
• Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants Cochrane Database of Systematic Reviews, 2022
• Environmental and financial impacts of perioperative paracetamol use: a multicentre international life-cycle analysis British Journal of Anaesthesia, 2024
• Heterogeneous Photo-Fenton Catalyzed by Natural Iron Ore from a City of Bandjéli in Northwestern of Togo, for the Elimination of Paracetamol in Aqueous Media 2025
• Metal nanocrystals and nanoclusters with paracetamol passivation and for paracetamol detection: a critical review Nanoscale advances, 2026
• The carbon footprint of emergency care for low back pain in Sydney, Australia, 2016–2021 2026
• Spinal anesthesia as an adjunct to general anesthesia for robotic assisted laparoscopic prostatectomy – a randomised placebo-controlled trial 2026