Browse studies, page 1017

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• Delayed Sleep Phase and Risk for Adolescent Substance Use ClinicalTrials.gov · COMPLETED, 2024
• The Sleep Well Observation Study: a Single-arm, Open-label, Prospective Intra-individual Change Controlled, Exploratory Pilot Study ClinicalTrials.gov · COMPLETED, 2023
• Contribution to the Understanding of the Involvement of Mechanical Ventilation in ICU Patients Sleep Disorders ClinicalTrials.gov · COMPLETED, 2015
• Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism ClinicalTrials.gov · COMPLETED, 2019
• Evning Exposure to Computer Screen Disrupts Sleep, Attention and Biological Rhythms ClinicalTrials.gov · COMPLETED, 2016
• The Effectiveness of Melatonin in Prevention of Radiation-induced Oral Mucositis ClinicalTrials.gov · COMPLETED, 2018
• A Combined Supplementation of Rosemary and Daylily for Enhancing Sleep Quality in Middle-Aged Adults ClinicalTrials.gov · COMPLETED, 2025
• Efficacy and Safety of Melatonin for Pain Relief in Knee Osteoarthritis Patients: A Randomized, Double-Blind, Placebo-Controlled Trial ClinicalTrials.gov · COMPLETED, 2025
• Characterisation of Circadian Rhythm in Autistic Spectrum Disorder : a Clinical, Biochemical and Genetic Study ClinicalTrials.gov · COMPLETED, 2013
• The Impact of Ergonomic Circadian Light on Hospitalized Stroke Patients in a Rehabilitation Unit ClinicalTrials.gov · COMPLETED, 2016
• Supplement 5-ALA And Sleep And Mood Study ClinicalTrials.gov · COMPLETED, 2012
• Does Melatonin Treatment Affect Glucose Tolerance Among Individuals With a Variant (rs10830963) of the Melatonin Receptor 1B (MTNR1B) Gene? ClinicalTrials.gov · COMPLETED, 2014
• Randomized Open-label Trial Evaluating Light Therapy on Sleep Quality in Dialysis Patients ClinicalTrials.gov · COMPLETED, 2020
• A Randomized, Double-blind, Placebo-controlled, Parallel Study Investigating the Efficacy of a Probiotic Blend on Stress in Adolescents With Moderate Perceived Stress ClinicalTrials.gov · COMPLETED, 2024
• Effects of Ramelteon on Sleep and Neurobehavioral Performance in a Simulated Night Shift Preceded by a Sleep Opportunity ClinicalTrials.gov · COMPLETED, 2008
• The Effect of Exercise on Sleep Quality and Nocturnal Fat Oxidation in Individuals With Metabolic Syndrome ClinicalTrials.gov · TERMINATED, 2021
• Sensitization of Human Circadian Responses to Light ClinicalTrials.gov · COMPLETED, 2020
• Delayed Sleep Phase Syndrome in Adolescents and Young Adults. Sleep, Personality, Developmental History, Circadian Rhythm, Daytime Functioning and Treatment ClinicalTrials.gov · COMPLETED, 2012
• A Single-Center, Open-Label, Exploratory Self-Controlled Study of NatureU Sweet Dream on Deep Sleep Duration and Deep Sleep Percentage in Adults With Sleep Disturbance ClinicalTrials.gov · COMPLETED, 2024
• A Randomized, Double-blind, Placebo-controlled, Multi-center Study of the Effects of VEC-162 on Circadian Rhythm in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2005
• "Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance" ClinicalTrials.gov · COMPLETED, 2008
• Repurposing Melatonin Receptor Agonists as Adjunct Treatments for Smoking Cessation ClinicalTrials.gov · COMPLETED, 2018
• An Interventional Clinical Study to Investigate the Effect of Oral Administration of Suanzaoren Decoction and Huanglian Wendan Decoction on Human Biorhythms in Patients With Insomnia ClinicalTrials.gov · COMPLETED, 2024
• Exploratory Study of Melatonin Induced Sleep Regularization in Severe Brain Injury ClinicalTrials.gov · TERMINATED, 2018
• Double-blind Randomized Control Trial Versus Placebo to Assess the Daily Consumption Audistim® Day/Night on Hearing Comfort and Quality of Life of Patients With Chronic Tinnitus ClinicalTrials.gov · COMPLETED, 2023
• Melatonin Randomized Trial for Insomnia in the Elderly ClinicalTrials.gov · COMPLETED, 2008
• The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet Lag ClinicalTrials.gov · COMPLETED, 2007
• Getting SMART for Pediatric Epilepsy (Sleep, Melatonin, and Research Trial, SMART) ClinicalTrials.gov · COMPLETED, 2025
• Melatonin Postoperative Sleep Study in Breast Cancer Patients ClinicalTrials.gov · TERMINATED, 2008
• The Effect of an Eye Mask-Based Blackout Protocol on Patients' Sleep Quality and Melatonin Levels: A Randomised Controlled Trial ClinicalTrials.gov · COMPLETED, 2025
• Enhancing Circadian Signal to Improve Cardiometabolic Function in Aging ClinicalTrials.gov · COMPLETED, 2024
• The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression ClinicalTrials.gov · COMPLETED, 2016
• A Double-Blind, Placebo-Controlled Study of Circadin™ for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects ClinicalTrials.gov · COMPLETED, 2007
• Double Blind Randomized Study Controlled by Placebo and Amitriptylin to Evaluate the Efficacy of Melatonin in the Preventive Treatment of Migraine ClinicalTrials.gov · COMPLETED, 2012
• The Role of the Circadian System in Neurological Sleep-wake Disorders: Assessment of Circadian and Homeostatic Sleep-wake Regulation and Vigilance With a Poly-nap Protocol ClinicalTrials.gov · COMPLETED, 2020
• Adolescent Circadian Misalignment: Mechanistic Studies of Sleep and Light ClinicalTrials.gov · COMPLETED, 2025
• Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements Nutrients, 2022
• Circadian Rhythm Dysregulation and Restoration: The Role of Melatonin Nutrients, 2021
• Evaluating the Potential Effect of Melatonin on the post-Cardiac Surgery Sleep Disorder The journal of Tehran Heart Center, 2015
• The effect of melatonin treatment on postural stability, muscle strength, and quality of life and sleep in postmenopausal women: a randomized controlled trial Nutrix Journal, 2015
• Nocturnal Melatonin Profiles in Patients with Delayed Sleep-Wake Phase Disorder and Control Sleepers Journal of Biological Rhythms, 2015
• Exogenous melatonin for sleep disorders in neurodegenerative diseases: a meta-analysis of randomized clinical trials Neurological Sciences, 2015
• Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials American Journal of Alzheimers Disease & Other Dementias, 2015
• Melatonin improves sleep in children with epilepsy: randomized, double-blind cross-over study Sleep Medicine, 2015
• Effects of earplugs and eye masks combined with relaxing music on sleep, melatonin and cortisol levels in ICU patients: a randomized controlled trial Critical Care, 2015
• Melatonin is required for the circadian regulation of sleep Neuron, 2015
• Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization Translational Psychiatry, 2023
• Sleep, Melatonin, and the Menopausal Transition: What Are the Links? Sleep Science, 2016
• Comparative Review of Approved Melatonin Agonists for the Treatment of Circadian Rhythm Sleep‐Wake Disorders Pharmacotherapy, 2016
• Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology Diabetes, 2016
• Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders Cellular and molecular neurobiology, 2023
• Melatonin Supplementation for Children With Atopic Dermatitis and Sleep Disturbance: A Randomized Clinical Trial JAMA pediatrics, 2016
• Randomized Controlled Trial of Melatonin for Sleep Disturbance in Dravet Syndrome: The DREAMS Study Journal of Clinical Sleep Medicine (JCSM), 2018
• Long-Term Melatonin Therapy for Adolescents and Young Adults with Chronic Sleep Onset Insomnia and Late Melatonin Onset: Evaluation of Sleep Quality, Chronotype, and Lifestyle Factors Compared to Age-Related Randomly Selected Population Cohorts Healthcare, 2018
• Melatonin and sleep in preventing hospitalized delirium: A randomized clinical trial American Journal of Medicine, 2018
• Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder Sleep Medicine, 2018
• The effects of spectral tuning of evening ambient light on melatonin suppression, alertness and sleep Physiology and Behavior, 2017
• Strategies to decrease social jetlag: Reducing evening blue light advances sleep and melatonin European Journal of Neuroscience, 2018
• Melatonin, sleep, and circadian rhythm disorders Seminars in Clinical Neuropsychiatry, 2000
• Melatonin in sleep disorders Neurología, 2018
• Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis Archives of Disease in Childhood, 2018
• Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial PLoS Medicine, 2018
• Effects of Melatonin and Bright Light Treatment in Childhood Chronic Sleep Onset Insomnia With Late Melatonin Onset: A Randomized Controlled Study Sleep, 2017
• Efficacy of melatonin for sleep disturbance following traumatic brain injury: a randomised controlled trial BMC Medicine, 2018
• Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders Sleep Medicine Reviews, 2017
• Melatonin, Sleep, and Shift Work Adaptation Journal of Occupational and Environmental Medicine, 2005
• A review of sleep disorders and melatonin Neurological Research, 2017
• Sleep well. Untangling the role of melatonin MT1 and MT2 receptors in sleep Journal of Pineal Research, 2019
• The use of melatonin in adult psychiatric disorders: Expert recommendations by the French institute of medical research on sleep (SFRMS) L'Encephale, 2019
• Prophylactic use of exogenous melatonin and melatonin receptor agonists to improve sleep and delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trials Sleep and Breathing, 2019
• Efficacy and safety of melatonin for sleep onset insomnia in children and adolescents: a meta-analysis of randomized controlled trials Sleep Medicine, 2019
• Influence of Dietary Sources of Melatonin on Sleep Quality: A Review Journal of Food Science, 2019
• Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis Frontiers in neuroendocrinology (Print), 2019
• Pediatric sleep disturbances and treatment with melatonin Journal of Translational Medicine, 2019
• Efficacy and safety of supplemental melatonin for delayed sleep-wake phase disorder in children: an overview Sleep Medicine: X, 2020
• The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review Sleep Medicine, 2020
• Differential Function of Melatonin MT1 and MT2 Receptors in REM and NREM Sleep Frontiers in Endocrinology, 2019
• Efficacy of melatonin for sleep disturbance in middle-aged primary insomnia: a double-blind, randomised clinical trial Sleep Medicine, 2020
• Melatonin in sleep disorders Neurología, 2020
• Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review CNS Drugs, 2019
• Changing color and intensity of LED lighting across the day impacts on circadian melatonin rhythms and sleep in healthy men Journal of Pineal Research, 2020
• Elderly as a High-risk Group during COVID-19 Pandemic: Effect of Circadian Misalignment, Sleep Dysregulation and Melatonin Administration Sleep and Vigilance, 2020
• Clinical impact of melatonin on breast cancer patients undergoing chemotherapy; effects on cognition, sleep and depressive symptoms: A randomized, double-blind, placebo-controlled trial PLoS ONE, 2020
• The Effects of Melatonin Supplementation on Sleep Quality and Assessment of the Serum Melatonin in ICU Patients: A Randomized Controlled Trial Critical Care Medicine, 2020
• New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation British Journal of Pharmacology, 2018
• Pharmacokinetics of exogenous melatonin in relation to formulation, and effects on sleep: A systematic review Sleep Medicine Reviews, 2021
• The effect of melatonin on sleep quality and insomnia in patients with cancer: a systematic review study Sleep Medicine, 2021
• Melatonin effects on sleep quality and outcomes of COVID‐19 patients: An open‐label, randomized, controlled trial Journal of Medical Virology, 2021
• Melatonin as a Potential Adjuvant Treatment for COVID-19 beyond Sleep Disorders International Journal of Molecular Sciences, 2021
• International Expert Opinions and Recommendations on the Use of Melatonin in the Treatment of Insomnia and Circadian Sleep Disturbances in Adult Neuropsychiatric Disorders Frontiers in Psychiatry, 2021
• Melatonin Alleviates Acute Sleep Deprivation-Induced Memory Loss in Mice by Suppressing Hippocampal Ferroptosis Frontiers in Pharmacology, 2021
• Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials Nature and Science of Sleep, 2022
• Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials Journal of Neurology, 2021
• High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults Journal of Pineal Research, 2022
• Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: a systematic review and meta-analysis Neuroscience and Biobehavioral Reviews, 2022
• Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis Progress in Neuro-psychopharmacology and Biological Psychiatry, 2022
• Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness Current Psychiatry Reports, 2022
• Melatonin Treatment for Sleep Disorders in Parkinson's Disease: A Meta-Analysis and Systematic Review Frontiers in Aging Neuroscience, 2022
• Neuroprotective Effect of Melatonin on Sleep Disorders Associated with Parkinson’s Disease Antioxidants, 2023
• Melanopic irradiance defines the impact of evening display light on sleep latency, melatonin and alertness Communications Biology, 2023