Browse studies, page 1303
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- Levofloxacin-Induced QTc Prolongation Depends on the Time of Drug Administration CPT: Pharmacometrics & Systems Pharmacology, 2016
- Maximizing Pharmacodynamics with High-Dose Levofloxacin Hospital Pharmacy, 2005
- Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial Critical Care, 2019
- Bronchopulmonary pharmacokinetic and pharmacodynamic profiles of levofloxacin 750 mg once daily in adults undergoing treatment for acute exacerbation of chronic bronchitis Pulmonary Pharmacology & Therapeutics, 2012
- Clinical validation of antimicrobial dosing regimens for continuous renal replacement therapy based on an ex vivo dosing algorithm Journal of Antimicrobial Chemotherapy, 2025
- Efficacy of ultra-short course chemotherapy for new smear positive drug susceptible pulmonary tuberculosis: study protocol of a multicenter randomized controlled clinical trial BMC Infectious Diseases, 2017
- Efficacy and safety of levofloxacin in the context of other contemporary fluoroquinolones: a review Current Therapeutic Research, 2003
- Open-label crossover study to determine pharmacokinetics and penetration of two dose regimens of levofloxacin into inflammatory fluid Antimicrobial agents and chemotherapy, 1995
- Pharmacokinetics and pharmacodynamics of gatifloxacin against Streptococcus pneumoniae and Staphylococcus aureus in a granulocyte-rich exudate Antimicrobial agents and chemotherapy, 2002
- Drug interactions with clinafloxacin Antimicrobial agents and chemotherapy, 2001
- Evaluation of tigecycline penetration into colon wall tissue and epithelial lining fluid using a population pharmacokinetic model and Monte Carlo simulation Antimicrobial agents and chemotherapy, 2007
- Levofloxacin pharmacokinetics in adult cystic fibrosis Chest, 2007
- Penetration of meropenem into epithelial lining fluid of patients with ventilator-associated pneumonia Antimicrobial agents and chemotherapy, 2011
- Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103) Cancer chemotherapy and pharmacology, 2014
- Dose findings of antofloxacin hydrochloride for treating bacterial infections in an early clinical trial using PK-PD parameters in healthy volunteers Acta pharmacologica Sinica, 2012
- Comparison of the pharmacodynamics of biapenem in bronchial epithelial lining fluid in healthy volunteers given half-hour and three-hour intravenous infusions Antimicrobial agents and chemotherapy, 2009
- Optimal dose finding of garenoxacin based on population pharmacokinetics/pharmacodynamics and Monte Carlo simulation European journal of clinical pharmacology, 2012
- Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases Scientific reports, 2015
- A phase 1/2 study of carfilzomib in Japanese patients with relapsed and/or refractory multiple myeloma British journal of haematology, 2016
- Oral Candida in Patients with Fixed Orthodontic Appliance: In Vitro Combination Therapy BioMed research international, 2017
- Influence of borderline cefepime MIC on the outcome of cefepime-susceptible Pseudomonas aeruginosa bacteremia treated with a maximal cefepime dose: a hospital-based retrospective study Annals of clinical microbiology and antimicrobials, 2017
- Pharmacokinetics, Safety, and Tolerability of Single-Dose Intravenous Moxifloxacin in Pediatric Patients: Dose Optimization in a Phase 1 Study Journal of clinical pharmacology, 2019
- Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination With Fludarabine and Cytarabine, in Pediatric Relapsed or Refractory Acute Leukemia Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016
- Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study BMJ open, 2018
- Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial Trials, 2022
- Population Pharmacokinetic Model and Limited Sampling Strategies for Personalized Dosing of Levofloxacin in Tuberculosis Patients Antimicrobial agents and chemotherapy, 2018
- Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): study protocol for a phase III randomized controlled trial Trials, 2022
- Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP) BMJ open, 2022
- Pharmacokinetics and pharmacodynamics of oral pradofloxacin administration in dogs American journal of veterinary research, 2018
- Testing novel strategies for patients hospitalised with HIV-associated disseminated tuberculosis (NewStrat-TB): protocol for a randomised controlled trial Trials, 2024
- Application of Visual Gene Clip-Based Tailored Therapy for the Eradication of Helicobacter pylori BioMed research international, 2021
- Multiple-dose safety and pharmacokinetics of oral garenoxacin in healthy subjects Antimicrobial agents and chemotherapy, 2003
- Absence of an effect of levofloxacin on warfarin pharmacokinetics and anticoagulation in male volunteers Journal of clinical pharmacology, 1996
- Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections Antimicrobial agents and chemotherapy, 2001
- Tigecycline population pharmacokinetics in patients with community- or hospital-acquired pneumonia Antimicrobial agents and chemotherapy, 2010
- Pharmacokinetics-pharmacodynamics of tigecycline in patients with community-acquired pneumonia Antimicrobial agents and chemotherapy, 2012
- Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects British journal of clinical pharmacology, 2014
- Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis Antimicrobial agents and chemotherapy, 2011
- Evaluation of Daptomycin Exposure and Efficacy and Safety Endpoints To Support Risk-versus-Benefit Considerations Antimicrobial agents and chemotherapy, 2015
- Clinical outcomes of extended versus intermittent administration of piperacillin/tazobactam for the treatment of hospital-acquired pneumonia: a randomized controlled trial European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2017
- A Randomized Study of the Single-Dose Safety, Pharmacokinetics, and Food Effect of Chinfloxacin and Its Effect on Thorough QT/QTc Interval in Healthy Chinese Volunteers Antimicrobial agents and chemotherapy, 2018
- Pharmacometrics-based dose selection of levofloxacin as a treatment for postexposure inhalational anthrax in children Antimicrobial agents and chemotherapy, 2010
- Population pharmacokinetics and pharmacodynamics of ofloxacin in South African patients with multidrug-resistant tuberculosis Antimicrobial agents and chemotherapy, 2012
- Pharmacokinetics and pharmacodynamics of multiple-dose intravenous nemonoxacin in healthy Chinese volunteers Antimicrobial agents and chemotherapy, 2015
- The Prognostic Impact of Dose-attenuated R-CHOP Therapy for Elderly Patients with Diffuse Large B-cell Lymphoma Internal medicine (Tokyo, Japan), 2018
- Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus Arthritis & rheumatology (Hoboken, N.J.), 2017
- Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia The Journal of antimicrobial chemotherapy, 2022
- BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections Nature communications, 2024
- Comparison the cost-efficacy of furazolidone-based versus clarithromycin-based quadruple therapy in initial treatment of Helicobacter pylori infection in a variable clarithromycin drug-resistant region, a single-center, prospective, randomized, open-label study Medicine, 2019
- Optimized dual therapy for treatment-naive patients of Helicobacter pylori infection: A large-scale prospective, multicenter, open-label, randomized controlled study Helicobacter, 2022
- Aqueous humour concentrations after topical apPlication of combinEd levofloxacin-dexamethasone eye dRops and of its single components: a randoMised, assEssor-blinded, parallel-group study in patients undergoing cataract surgery: the iPERME study European journal of clinical pharmacology, 2020
- Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections: A Phase IIb Randomized Clinical Trial Annals of surgery, 2023
- Keverprazan, a novel potassium-competitive acid blocker: Multiple oral doses safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy subjects Clinical and translational science, 2023
- Pharmacokinetics of levofloxacin in non-lactating goats and evaluation of drug effects on resistance in coliform rectal flora Research in veterinary science, 2020
- Immediate or high-dose antituberculosis therapy for HIV-related sepsis in Tanzania and Uganda (ATLAS): a phase 3, open-label, randomised, controlled, 2 × 2 factorial, superiority trial The Lancet. Infectious diseases, 2026
- Towards pharmacokinetic boosting of phenoxymethylpenicillin (penicillin-V) using probenecid for the treatment of bacterial infections Scientific reports, 2024
- Different Doses of Ilaprazole for Dual Therapy Versus Bismuth-Quadruple Therapy for Helicobacter pylori Infection: A Three-Arm, Randomized Clinical Trial Helicobacter, 2025
- Quadruple, sequential, and concomitant first-line therapies for H. pylori eradication: a prospective, randomized study Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2018
- Analysis of efficacy and safety of linezolid-based chemotherapeutic regimens for patients with postoperative multidrug-resistant spinal tuberculosis International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022
- Analysis of the drug therapy of gatifloxacin and levofloxacin in the treatment of acute bacterial conjunctivitis Pakistan journal of pharmaceutical sciences, 2018
- Evaluation of efficacy and safety of Lacticaseibacillus rhamnosus LRa05 in the eradication of Helicobacter pylori: a randomized, double-blind, placebo-controlled trial Frontiers in immunology, 2024
- Efficacy and safety of 8-week regimens for the treatment of rifampicin-susceptible pulmonary tuberculosis (TRUNCATE-TB): a prespecified exploratory analysis of a multi-arm, multi-stage, open-label, randomised controlled trial The Lancet. Infectious diseases, 2025
- Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial JAMA, 2018
- Randomized Clinical Trial of High-Dose Rifampicin With or Without Levofloxacin Versus Standard of Care for Pediatric Tuberculous Meningitis: The TBM-KIDS Trial Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022
- Oral Regimens for Rifampin-Resistant, Fluoroquinolone-Susceptible Tuberculosis The New England journal of medicine, 2025
- Six months therapy for tuberculous meningitis The Cochrane database of systematic reviews, 2016
- SARS-CoV-2-neutralising monoclonal antibodies for treatment of COVID-19 The Cochrane database of systematic reviews, 2021
- Real-world use of ceftolozane/tazobactam: a systematic literature review Antimicrobial resistance and infection control, 2021
- Gaps in Drug Dosing for Obese Children: A Systematic Review of Commonly Prescribed Emergency Care Medications Clinical therapeutics, 2015
- Analysis of the assessment of antimicrobial susceptibility. Non-typhoid Salmonella in meat and meat products as model (systematic review) BMC microbiology, 2021
- d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018
- Managing community acquired pneumonia in the elderly - the next generation of pharmacotherapy on the horizon Expert opinion on pharmacotherapy, 2017
- Evaluation of evidence for pharmacokinetics-pharmacodynamics-based dose optimization of antimicrobials for treating Gram-negative infections in neonates The Indian journal of medical research, 2017
- Pharmacokinetics of antiretroviral and tuberculosis drugs in children with HIV/TB co-infection: a systematic review The Journal of antimicrobial chemotherapy, 2020
- Improving antibacterial prescribing safety in the management of COPD exacerbations: systematic review of observational and clinical studies on potential drug interactions associated with frequently prescribed antibacterials among COPD patients The Journal of antimicrobial chemotherapy, 2019
- Antimicrobial stewardship implementation before and during the COVID-19 pandemic in the acute care settings: a systematic review BMC public health, 2023
- Dose Recommendations for Common Drugs in Patients with Liver Cirrhosis: A Systematic Literature Review Clinical drug investigation, 2023
- A Systematic Review of Studies Reporting Antibiotic Pharmacokinetic Data in the Cerebrospinal Fluid of Critically Ill Patients with Uninflamed Meninges Antimicrobial agents and chemotherapy, 2020
- A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases PLoS neglected tropical diseases, 2023
- Intensified Antituberculosis Therapy Regimen Containing Higher Dose Rifampin for Tuberculous Meningitis: A Systematic Review and Meta-Analysis Frontiers in medicine, 2022
- Updated antimicrobial dosing recommendations for obese patients Antimicrobial agents and chemotherapy, 2024
- Systematic review of ceftaroline fosamil in the management of patients with methicillin-resistant Staphylococcus aureus pneumonia European respiratory review : an official journal of the European Respiratory Society, 2023
- Prescribing Cascades: An Umbrella Review and Updated Systematic Review Drugs & aging, 2026
- Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: A systematic review International journal of antimicrobial agents, 2019
- Antibiotics for community-acquired pneumonia in adult outpatients The Cochrane database of systematic reviews, 2014
- Emerging infections in vulnerable hosts: Stenotrophomonas maltophilia and Elizabethkingia anophelis Current opinion in infectious diseases, 2023
- Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review PloS one, 2019
- Preclinical models to optimize treatment of tuberculous meningitis - A systematic review Tuberculosis (Edinburgh, Scotland), 2020
- A comparison of fluoroquinolones versus other antibiotics for treating enteric fever: meta-analysis BMJ (Clinical research ed.), 2009
- Systematic Review and Meta-analyses of the Effect of Chemotherapy on Pulmonary Mycobacterium abscessus Outcomes and Disease Recurrence Antimicrobial agents and chemotherapy, 2017
- Antibiotics for ventilator-associated pneumonia The Cochrane database of systematic reviews, 2016
- Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis The European respiratory journal, 2023
- Efficacy and safety of novel glycopeptides versus vancomycin for the treatment of gram-positive bacterial infections including methicillin resistant Staphylococcus aureus: A systematic review and meta-analysis PloS one, 2021
- Meta-Analysis of Drug Delivery Approaches for Treating Intracellular Infections Pharmaceutical research, 2022
- First-line Eradication of Helicobacter pylori Infection with High-Dose Amoxicillin and Vonoprazan: A Systematic Review and Meta-analysis The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2025
- Minocycline in the eradication of Helicobacter pylori infection: A systematic review and meta-analysis World journal of gastroenterology, 2024
- Efficacy and safety of early antibiotic de-escalation in febrile neutropenia for patients with hematologic malignancy: a systematic review and meta-analysis Antimicrobial agents and chemotherapy, 2025
- Continuous versus intermittent infusion of β-lactams in patients with sepsis and septic shock: a systematic review and meta-analysis BMC infectious diseases, 2025
- Postexposure Prophylaxis and Treatment of Bacillus anthracis Infections: A Systematic Review and Meta-analyses of Animal Models, 1947-2019 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022
- Effectiveness and safety of tuberculosis preventive treatment for contacts of patients with multidrug-resistant tuberculosis: a systematic review and meta-analysis Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2024
