Browse studies, page 708

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• Tadalafil for treatment of erectile dysfunction in men on antidepressants Journal of Clinical Psychopharmacology, 2007
• Dissolution enhancement of tadalafil by liquisolid technique Pharmaceutical Development and Technology, 2016
• Efficacy of Continuous Dosing of Tadalafil Once Daily vs Tadalafil On Demand in Clinical Subgroups of Men with Erectile Dysfunction: A Descriptive Comparison Using the Integrated Tadalafil Databases The Journal of Sexual Medicine, 2016
• IC351 (tadalafil, Cialis): update on clinical experience International Journal of Impotence Research, 2002
• Both Tadalafil and Dexamethasone May Reduce the Incidence of High-Altitude Pulmonary Edema Annals of Internal Medicine, 2006
• Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects The Journal of Clinical Pharmacology, 2008
• Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia The Journal of Urology, 2007
• Tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones The Journal of Urology, 2003
• Physicochemical characterization of solid dispersion systems of tadalafil with poloxamer 407 Acta Pharmaceutica, 2009
• Initial experience with tadalafil in pediatric pulmonary arterial hypertension Pediatric Cardiology, 2012
• Efficacy and Safety of Tadalafil for the Treatment of Erectile Dysfunction: Results of Integrated Analyses The Journal of Urology, 2002
• Tadalafil (cialis™) for MEN with erectile dysfunction International Journal of Clinical Practice, 2002
• Effects of tadalafil on erectile dysfunction in men with diabetes Diabetes Care, 2002
• Overview of the cardiovascular effects of tadalafil European Heart Journal Supplements, 2002
• Comparison of Efficacy, Safety, and Tolerability of On-Demand Tadalafil and Daily Dosed Tadalafil for the Treatment of Erectile Dysfunction The Journal of Sexual Medicine, 2005
• Efficacy and Safety of Daily Tadalafil in Men with Erectile Dysfunction Previously Unresponsive to On-Demand Tadalafil The Journal of Sexual Medicine, 2004
• Tadalafil in the treatment of erectile dysfunction Therapeutics and Clinical Risk Management, 2008
• The efficacy and safety of tadalafil: an update British Journal of Urology, 2004
• Tadalafil therapy for pulmonary arterial hypertension Circulation, 2009
• Tadalafil pharmacokinetics in healthy subjects British Journal of Clinical Pharmacology, 2005
• The Effect of Selective PDE-5 Inhibition on Capillary Recruitment, Glucose Uptake and Endothelial Function Following a Mixed Meal in Patients With Type 2 Diabetes Patients ClinicalTrials.gov · TERMINATED, 2011
• Double-Blind, Placebo Controlled Randomized Study of Co-Administering Testosterone With PDE5 Inhibitors in Patients Non-Responders to PDE5 Inhibitors Alone ClinicalTrials.gov · COMPLETED, 2007
• Assessment of Serum YKL-40 Level and Platelets Indices Among Patients With Diabetic Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2022
• A Randomized, Open-label, Oral Single Dosing, Two-way Crossover Clinical Trial to Evaluate the Safety and Pharmacokinetic Profiles of CKD-397 in Healthy Male Subjects ClinicalTrials.gov · COMPLETED, 2015
• Administration of an Oral PDE5 Inhibitor, Tadalafil in Conjunction With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma ClinicalTrials.gov · TERMINATED, 2014
• Effect of PDE5 Inhibition on Adipose Metabolism in Humans ClinicalTrials.gov · COMPLETED, 2025
• Efficacy and Tolerability of Tadalafil 5mg Once Daily Versus Darifenacin for Ureteric Stent Related Symptoms ClinicalTrials.gov · COMPLETED, 2022
• Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention ClinicalTrials.gov · COMPLETED, 2010
• Actual Use Trial to Switch Tadalafil 5 mg Tablets From Prescription to Over-the-Counter ClinicalTrials.gov · COMPLETED, 2026
• A Multi-center, Randomized, Double-blinded, Double-dummy, Parallel Group, 48-week, Phase III Clinical Trial to Evaluate the Efficacy and Safety of DKF-313 in Patients With Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2023
• Safety And Efficacy Of L-Arginine Monotherapy Versus Tadalafil Monotherapy Versus Their Combination In Men With Erectile Dysfunction; A Prospective Randomized Study ClinicalTrials.gov · COMPLETED, 2025
• A Randomised, Double-blind, Double-dummy, Parallel-group, Active-controlled Study Evaluating the Efficacy of Vardenafil Versus Tadalafil When Intercourse is Attempted Within 45 Minutes of Administration in Subjects With Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2004
• Efficacy and Safety of Tadalafil, Tamsulosin, and Their Combinations in Treating Lower Urinary Tract Symptoms in BPH Patients With Prostate Volumes ≤ 40 ml: A Prospective Comparative Study ClinicalTrials.gov · COMPLETED, 2024
• Single-center, Open-label, Single-dose, 2-period, Randomized, Crossover Phase 1 Study to Demonstrate Bioequivalence of Tadalafil Administered as a Fixed Dose Combination Formulation of Macitentan/Tadalafil (10 mg/40 mg) and as the Free Combination of 10 mg Macitentan (Opsumit) and 40 mg Tadalafil (Adcirca), and to Assess the Effect of Food on the Pharmacokinetics of the Fixed Dose Formulation of Macitentan/Tadalafil (10 mg/40 mg) in Healthy Adult Participants ClinicalTrials.gov · COMPLETED, 2020
• Phase II Study of Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in Patients With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers ClinicalTrials.gov · TERMINATED, 2022
• Tadalafil 5 mg Once a Day Compared to Placebo in Improving Erectile Dysfunction and Sexual Quality of Life ClinicalTrials.gov · COMPLETED, 2008
• An Evaluation of Tadalafil and Sildenafil Treatment in Men With Erectile Dysfunction in China ClinicalTrials.gov · COMPLETED, 2012
• Comparison Between The Effect of Intracavernosal Injection of Platelet-Rich Plasma as a Single Agent vs Daily Oral 5 Phosphodiesterase Inhibitor Intake as a Single Agent Vs Combination In Improving of Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2024
• The Effect of Combination Therapy Using Li-ESWT (Low Intensity Extracorporeal Shockwave Therapy) and PDE-5 Inhibitor in Patients With Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2020
• The Efficacy of Phosphodiesterase Inhibitors in Patients With Group 2 Pulmonary Hypertension ClinicalTrials.gov · COMPLETED, 2025
• A Randomized, Double Blind, Placebo-controlled Study to Evaluate the Effect of Tadalafil Once Daily for 8 Weeks on Prostatic Blood Flow and Perfusion Parameters in Men With Signs and Symptoms of Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2012
• Clinical Efficacy of Phosphodiesterase-5 Inhibitor Tadalafil in Eisenmenger Syndrome - A Randomised, Placebo Controlled, Double Blind, Crossover Study ClinicalTrials.gov · COMPLETED, 2010
• Assessment of Single-dose Oral Tadalafil Pharmacokinetic Characteristics When Simultaneously Co-administered With Single-dose and Steady-state Tipranavir/Ritonavir 500 mg/200 mg to Healthy Male Volunteers ClinicalTrials.gov · COMPLETED
• Tadalafil for the Treatment of Secondary Raynaud's Phenomenon ClinicalTrials.gov · COMPLETED, 2010
• Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride ClinicalTrials.gov · COMPLETED, 2013
• Comparative Study Between Silodosin , Tamsulosin , Silodosin Plus Tadalafil and Tamsulosin Plus Tadalafil As a Medical Expulsive Therapy for Lower Ureteral Stones ClinicalTrials.gov · COMPLETED, 2024
• Single Dose Oral Bioequivalence Study of Macitentan and Tadalafil Filmcoated Tablets 10 Mg/40 Mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 Mg in Healthy Adult Male Subjects Under Fed Conditions ClinicalTrials.gov · COMPLETED, 2024
• A Study to Investigate the Pharmacokinetic Drug Interactions Between Dutasteride and Tadalafil in Healthy Male Subjects ClinicalTrials.gov · COMPLETED, 2016
• A Double-Blind Efficacy and Safety Study of the Phosphodiesterase Type 5 Inhibitor Tadalafil in Pediatric Patients With Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2021
• A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract ClinicalTrials.gov · COMPLETED, 2012
• Prospective Case Crossover Study to Assess Whether PDE5 Inhibitor Exposure in Men Increases the Risk for the Development of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) ClinicalTrials.gov · TERMINATED, 2018
• A Phase I Study of Ranolazine Acute Administration and Short Term Administration in Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2015
• Low Dose Tadalafil 5mg for Treatment of Female Overactive Bladder Syndrome :6 Months Follow up ClinicalTrials.gov · COMPLETED, 2022
• Daily Oral L-arginine Plus Tadalafil in Diabetic Patients With Erectile Dysfunction: A Double-blinded Randomized Controlled Clinical Trial ClinicalTrials.gov · COMPLETED, 2018
• A Phase 3, Randomized, Double Blind, Placebo and Tamsulosin Controlled, Parallel Design, Multinational Study to Evaluate the Efficacy and Safety of Tadalafil Once a Day Dosing for 12 Weeks in Asian Men With Signs and Symptoms of Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2010
• A Comparison of Psychosocial Outcomes Following Tadalafil Once a Day or PDE5 Inhibitor As Needed in Men With Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2009
• Investigational and Comparative Study to Assess Safety and Effectiveness of Tadalafil and Pentoxifyllin in the Management of Diabetic Nephropathy ClinicalTrials.gov · COMPLETED, 2023
• "Effect of Different Dosing Regimens of Tadalafil or Tamsulosin Combined With 5α-Reductase Inhibitors on Urinary and Sexual Outcomes in Benign Prostatic Hyperplasia: A Comparative Clinical Trial Study" ClinicalTrials.gov · COMPLETED, 2026
• A Multicenter, Parallel-Arm, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy and Safety of Tadalafil Administered Once Daily to Men With Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2005
• A Multi-centre, Randomised, Open-label, Home Use, Parallel Group, Clinical Investigation of Topically-applied MED3000 Gel and Oral Tadalafil (5 mg) Tablets for the Treatment of Erectile Dysfunction (ED) Over a 24 Week Period ClinicalTrials.gov · COMPLETED, 2022
• Skeletal Muscle Blood Flow in Becker Muscular Dystrophy ClinicalTrials.gov · TERMINATED, 2018
• Randomized, Placebo-Controlled, Double-Blind, Cross-Over Trial of the Efficacy and Safety of IC351 in Female Patients With Raynaud Phenomenon and Female Sexual Dysfunction Secondary to Systemic Sclerosis ClinicalTrials.gov · COMPLETED, 2002
• Pilot Study of Phosphodiesterase-5 Inhibitor Tadalafil (Cialis) as an Immunomodulator in Patients With Oral Cavity and Oropharyngeal Squamous Cell Carcinoma ClinicalTrials.gov · COMPLETED, 2015
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multinational Study to Evaluate the Efficacy and Safety of Daily Tadalafil for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2009
• A Randomized, Double-blind, Placebo-controlled Phase III Trial to Evaluate the Effectiveness of a Phosphodiesterase 5 Inhibitor, Tadalafil, in Prevention of Erectile Dysfunction in Patients Treated With Radiotherapy for Prostate Cancer ClinicalTrials.gov · COMPLETED, 2014
• A Randomized, Placebo-Controlled, Double-Blinded, Parallel, Phase 2a Study to Evaluate the Safety and Efficacy of LY2623091 in Patients With Primary Hypertension ClinicalTrials.gov · COMPLETED, 2015
• Tadalafil for Pulmonary Hypertension Associated With Chronic Lung Disease ClinicalTrials.gov · COMPLETED, 2019
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multicenter Study to Evaluate the Efficacy and Safety of Tadalafil Once-Daily Dosing for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia and Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2015
• A Multicenter Open-Label Study to Determine Treatment Preference of Tadalafil (IC351, LY450190) or Sildenafil Citrate in the Oral Treatment of Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2004
• Early Postoperative Triple Targeted Therapy in Patients With CHD-PAH in the "Grey Zone" ClinicalTrials.gov · COMPLETED, 2025
• Multi-center, Randomized，Placebo and Positive Controlled Clinical Study of TPN171H Tablets on Acute Haemodynamics in Patients with Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2022
• A Randomized, Double-Blind, Parallel, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tadalafil (2.5mg and 5mg) Administered Once Daily to Men With Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2006
• Efficacy of Intracavernosal Injection of Platelet-Rich Plasma Alone Versus Combined With Oral Tadalafil in The Management of Erectile Dysfunction; A Prospective Randomized Study ClinicalTrials.gov · COMPLETED, 2025
• LY2452473 Formulation Exploratory Bioavailability Study ClinicalTrials.gov · COMPLETED, 2011
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Global Multicenter Study to Evaluate the Efficacy and Safety of Tadalafil Once Daily Dosing for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2011
• A Randomized, Open-label, Single-dose, 2-treatment, 2-way, 2-period Crossover Study to Evaluate the Safety and the Pharmacokinetic Characteristics of DKF-313 in Healthy Male Volunteers ClinicalTrials.gov · COMPLETED, 2015
• Efficacy of Transcutaneous Electrical Neural Stimulation and Tadalafil in Men With Erectile Dysfunction: A Randomized, Double-Blind, Bi-centric, Placebo- and Sham-Controlled Trial ClinicalTrials.gov · COMPLETED, 2026
• An Extension Study to Evaluate the Long-Term Safety and Efficacy of the Phosphodiesterase Type 5 (PDE5) Inhibitor Tadalafil in the Treatment of Patients With Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2012
• A Single-center, Open-label, Single-dose, Randomized, 3-way Crossover Phase 1 Study in Healthy Adult Participants to Assess the Bioequivalence of the Combination of Macitentan/Tadalafil (10 mg/20 mg) Administered as a Fixed Dose Combination Formulation Compared to the Reference Free Combination of 10 mg Macitentan (Opsumit®) and 20 mg Tadalafil (Adcirca®) as Well as the Food Effect of the Fixed-dose Combination Formulation ClinicalTrials.gov · COMPLETED, 2022
• Functional Muscle Ischemia and PDE5A Inhibition in Becker Muscular Dystrophy ClinicalTrials.gov · COMPLETED, 2012
• A Study to Evaluate the Pharmacokinetics of Tadalafil Administered Once Daily in Japanese and Non-Japanese Subjects With Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2011
• Phase 3 Randomized Trial of Tadalafil and Glycemic Traits ClinicalTrials.gov · COMPLETED, 2013
• Efficacy and Safety of Once Daily Administration Tadalafil in Patients With Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2024
• "Low-intensity Shockwave Therapy (LiST) for the Treatment of Mild and Mild-to-moderate Vasculogenic Erectile Dysfunction: a Randomized Placebo Controlled Two-parallel Arms Trial, Comparing 6 Sessions, With Daily Tadalafil 5mg vs Placebo" ClinicalTrials.gov · COMPLETED, 2021
• A Randomized, Double-Blind, Placebo-Controlled, Parallel Design, Multinational Study to Evaluate the Efficacy and Safety of Tadalafil 2.5 and 5 mg Once Daily Dosing for 12 Weeks for the Treatment of Erectile Dysfunction and Signs and Symptoms of Benign Prostatic Hyperplasia in Men With Both Erectile Dysfunction and Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2010
• Tadalafil Once Daily Following As-Needed Phosphodiesterase Type 5 Inhibitor Treatment, an Assessment of Return to Normal Erectile Function ClinicalTrials.gov · COMPLETED, 2012
• A Randomized Trial of Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy ClinicalTrials.gov · TERMINATED, 2020
• A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design Study to Evaluate the Efficacy and Safety of Tadalafil Once-a-Day Dosing for 12 Weeks Followed by an Open-Label Extension to Evaluate the Long-Term Safety and Efficacy of Tadalafil in Japanese Men With Signs and Symptoms of Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2010
• Clinical Trial To Evaluate the Efficacy and Safety of CKD-397 in Benign Prostatic Hyperplasia Patients ClinicalTrials.gov · COMPLETED, 2016
• A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Tadalafil for Duchenne Muscular Dystrophy ClinicalTrials.gov · TERMINATED, 2016
• Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure ClinicalTrials.gov · TERMINATED, 2014
• Does Presence of Distress Due to Erectile Dysfunction Affect the Effect of Tadalafil on Sexual Life and Life Satisfaction? ClinicalTrials.gov · COMPLETED, 2004
• The Effect of Tadalafil on Cerebral Large Arteries in Stroke Patients ClinicalTrials.gov · COMPLETED, 2017
• A Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multicenter Study to Evaluate the Urodynamic Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia ClinicalTrials.gov · COMPLETED, 2008
• Phosphodiesterase-5 Inhibitor (Tadalafil) Two Weeks Administration Period Effects in Left Ventricle Diastolic Dysfunction and BNP Levels in Resistant Hypertensive Patients ClinicalTrials.gov · COMPLETED, 2012
• o A Prospective, Randomized, Open-Label, Phase II Study Evaluating the Efficacy of Tadalafil for the Prevention of Docetaxel-Induced Peripheral Neuropathy in Patients With Metastatic Prostate Cancer ClinicalTrials.gov · COMPLETED, 2024
• Effect of Tadalafil on the Quality of Life and Sexual Life in Erectile Dysfunction (ED) Patients Previously Treated With Other Oral ED Therapy ClinicalTrials.gov · COMPLETED, 2005
• An Open-label, Multicenter Study of Ambrisentan and a Phosphodiesterase Type-5 Inhibitor Combination Therapy in Subjects With Pulmonary Arterial Hypertension Who Have Demonstrated a Sub-Optimal Response to a Phosphodiesterase Type-5 Inhibitor ClinicalTrials.gov · COMPLETED, 2011
• A Randomized, Double-Blind, Parallel-Design, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tadalafil (2.5 mg and 5 mg) Administered Once Daily to Men With Diabetes Mellitus and Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2005
• A Randomized Placebo Controlled Trial of Tadalafil for Erectile Dysfunction in Patients With Cirrhosis ClinicalTrials.gov · COMPLETED, 2019