Browse studies, page 705

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Efficacy and safety of tadalafil 5 mg once-daily in Asian men with both lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: A phase 3, randomized, double-blind, parallel, placebo- and tamsulosin-controlled study International journal of urology : official journal of the Japanese Urological Association, 2019
A Phase I Study to Show the Relative Bioavailability and Bioequivalence of Fixed-Dose Combinations of Ambrisentan and Tadalafil in Healthy Subjects Clinical therapeutics, 2019
Outcomes and characteristics of cardiac arrest in children with pulmonary hypertension: A secondary analysis of the ICU-RESUS clinical trial Resuscitation, 2023
Cardiac function and tadalafil used for treating fetal growth restriction in pregnant women without cardiovascular disease The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019
Prognostic factors for changes in the timed 4-stair climb in patients with Duchenne muscular dystrophy, and implications for measuring drug efficacy: A multi-institutional collaboration PloS one, 2020
Clinical efficacy of tadalafil compared to sildenafil in treatment of moderate to severe canine pulmonary hypertension: a pilot study Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2019
Pharmacokinetics and safety of tadalafil in a paediatric population with pulmonary arterial hypertension: A multiple ascending-dose study British journal of clinical pharmacology, 2019
Disease progression rates in ambulatory Duchenne muscular dystrophy by steroid type, patient age and functional status Journal of comparative effectiveness research, 2023
Pharmacokinetic interaction between linagliptin and tadalafil in healthy Egyptian males using a novel LC-MS method Bioanalysis, 2019
Effects of Chaihu-Shugan-San capsule for psychogenic erectile dysfunction: Study protocol of a randomized placebo-controlled trial Medicine, 2019
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects Drug design, development and therapy, 2021
Efficacy of Tadalafil Therapy and Changes in Oxidative Stress Levels in Male Patients with Lower Urinary Tract Symptoms and Overactive Bladder Lower urinary tract symptoms, 2020
The efficacy of Tadalafil 5mg in the treatment of lower urinary tract symptoms in patients where alpha blocker treatments have failed in terms of lower urinary tract symptoms Archivos espanoles de urologia, 2019
4-Aminopyridine treatment for nerve injury resulting from radical retro-pubic prostatectomy: a single-center double-blind, randomized, placebo-controlled study Trials, 2024
The iSEARCH randomised controlled trial protocol: a pragmatic Australian phase III clinical trial of intrapartum sildenafil citrate to improve outcomes potentially related to intrapartum hypoxia BMJ open, 2024
Vericiguat Global Study in Participants with Chronic Heart Failure: Design of the VICTOR trial European journal of heart failure, 2025
Sildenafil Versus Placebo for Early Pulmonary Vascular Disease in Scleroderma (SEPVADIS): protocol for a randomized controlled trial BMC pulmonary medicine, 2024
Bioequivalence and food effect of a fixed-dose combination of macitentan and tadalafil: Adaptive design in the COVID-19 pandemic Pharmacology research & perspectives, 2021
Perioperative sildenafil citrate administration in hepatectomy: a study protocol of randomized controlled trial Trials, 2025
Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) BMJ open, 2022
Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re-PHIRE ESC heart failure, 2025
Assessment of the value of measuring soluble fms-like tyrosine kinase-1 and placental growth factor levels following administration of tadalafil to treat fetal growth restriction The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022
Ventilatory limitation to exercise in patients with HFpEF and obesity: No room to breathe Respiratory physiology & neurobiology, 2026
Innovative nitric oxide delivery technology for postoperative pulmonary hypertension in congenital heart disease patients: a clinical trial BMC cardiovascular disorders, 2025
New horizons in systemic sclerosis treatment: advances and emerging therapies in 2025 RMD open, 2025
CerebrAlcare Pills on CereBral Small VesseL DiseasE (CABLE) trial: rationale and design Stroke and vascular neurology, 2026
Fucoidan from Undaria pinnatifida Improves Benign Prostatic Hyperplasia Symptoms in Men: A Randomized, Double-Blind, Placebo-Controlled Study Research and reports in urology, 2026
Effects of riociguat on right ventricular size and function in pulmonary arterial hypertension (RIVER II): a prospective, phase IV study Respiratory research, 2026
Effect of Once-Daily Macitentan 75 mg on the Pharmacokinetics of Sildenafil, Riociguat, or Rosuvastatin in Healthy Male Participants Journal of clinical pharmacology, 2026
Successful Transition From Phosphodiesterase-5 Inhibitors to Riociguat Without a Washout Period in Patients With Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension: A Pilot Cohort Study Heart, lung & circulation, 2020
Tadalafil combined with behavioral therapy and psychological counseling for erectile dysfunction Zhonghua nan ke xue = National journal of andrology, 2021
Sexual satisfaction in men with erectile dysfunction: correlates and potential predictors The journal of sexual medicine, 2010
Response to treatment with tadalafil in men with erectile dysfunction who reported no successful intercourse attempts at baseline International journal of impotence research, 2008
Impact of pretreatment with carnitine and tadalafil on contrast-induced nephropathy in CKD patients Renal failure, 2019
Low-dose tadalafil improves arterial erectile dysfunction Zhonghua nan ke xue = National journal of andrology, 2009
A return to normal erectile function with tadalafil once daily after an incomplete response to as-needed PDE5 inhibitor therapy The journal of sexual medicine, 2014
Randomized study of adding tadalafil to existing ambrisentan in pulmonary arterial hypertension Hypertension research : official journal of the Japanese Society of Hypertension, 2014
Effects of iloprost combined with low dose tadalafil in adult congenital heart disease patients with severe pulmonary arterial hypertension: a single-center, open-label controlled study Zhonghua xin xue guan bing za zhi, 2014
Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy International braz j urol : official journal of the Brazilian Society of Urology, 2011
Effect of atorvastatin on erectile functions in comparison with regular tadalafil use. A prospective single-blind study International urology and nephrology, 2012
Treatment satisfaction with tadalafil or tamsulosin vs placebo in men with lower urinary tract symptoms ( LUTS ) suggestive of benign prostatic hyperplasia ( BPH ): results from a randomised, placebo‐controlled study BJU international, 2014
Vardenafil rescue rates of sildenafil nonresponders: objective assessment of 327 patients with erectile dysfunction Urology, 2006
Exercise training improves erectile dysfunction (ED) in patients with metabolic syndrome on phosphodiesterase-5 (PDE-5) inhibitors Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2013
Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial Trials, 2017
Effect of tadalafil on erectile dysfunction in male patients with diabetes mellitus Vojnosanitetski pregled, 2007
Tadalafil-induced improvement in left ventricular diastolic function in resistant hypertension European journal of clinical pharmacology, 2014
Evaluation of erectile function after laparoscopic radical prostatectomy in a single center The Canadian journal of urology, 2012
Long-term results of autologous venous grafts for penile morphological reconstruction Journal of andrology, 2007
Phosphodiesterase-5 inhibitor in Eisenmenger syndrome: a preliminary observational study Circulation, 2006
The efficacy of low-dose tadalafil in patients undergoing hemodialysis with end-stage renal disease Renal failure, 2017
Platelet count and function at high altitude and in high-altitude pulmonary edema Journal of applied physiology (Bethesda, Md. : 1985), 2006
Effect of tadalafil on blood flow, pain, and function in chronic cold Complex Regional Pain Syndrome: a randomized controlled trial BMC Musculoskeletal Disorders, 2008
Tadalafil 5 mg once‐daily therapy for men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: Results from a randomized, double‐blind, placebo‐controlled trial carried out in J apan and K orea International journal of urology, 2014
Adjuvant administration of probiotic effects on sexual function in depressant women undergoing SSRIs treatment: a double-blinded randomized controlled trial BMC psychiatry, 2024
Efficacy and safety of regular use of sildenafil in the treatment of penile erectile dysfunction Zhonghua nan ke xue = National journal of andrology, 2019
Intralesional collagenase Clostridium histolyticum vs. verapamil injections in males with Peyronie's Disease: A prospective, matched-pair, non-blinded, randomised clinical study comparing clinical outcomes and patient satisfaction rates Investigative and clinical urology, 2022
Treatment of experimentally induced benign prostatic hyperplasia with Tadalafil and castration in dogs Theriogenology, 2020
Riociguat in patients with sickle cell disease and hypertension or proteinuria (STERIO-SCD): a randomised, double-blind, placebo controlled, phase 1-2 trial The Lancet. Haematology, 2024
A randomized, double-blind, placebo-controlled study to evaluate sildenafil, ambrisentan combination therapy in pulmonary hypertension, particularly of Eisenmenger syndrome Indian heart journal, 2021
Comparison of cernitin pollen extract vs tadalafil therapy for refractory chronic prostatitis/chronic pelvic pain syndrome: A randomized, prospective study Neurourology and urodynamics, 2020
A sham-controlled randomised trial of pulmonary artery denervation for Group 1 pulmonary arterial hypertension: one-year outcomes of the PADN-CFDA trial EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2023
Intrapartum Sildenafil to Improve Perinatal Outcomes: A Randomized Clinical Trial JAMA, 2025
Efficacy and safety of tadalafil vs tamsulosin in lower urinary tract symptoms (LUTS) as a result of benign prostate hyperplasia (BPH)-open label randomised controlled study International journal of clinical practice, 2020
Dihydrotestosterone (DHT) rapidly increase after maximal aerobic exercise in healthy males: the lowering effect of phosphodiesterase's type 5 inhibitors on DHT response to exercise-related stress Journal of endocrinological investigation, 2021
Effects of phosphodiesterase V inhibition alone and in combination with BNP on cardiovascular and renal response to volume load in human preclinical diastolic dysfunction Physiological reports, 2021
Pharmacokinetic and Bioequivalence Evaluation of 2 Tadalafil Tablets in Healthy Male Chinese Subjects Under Fasting and Fed Conditions Clinical pharmacology in drug development, 2022
The effect of drug holidays on sexual dysfunction in men treated with selective serotonin reuptake inhibitors (SSRIs) other than fluoxetine: an 8-week open-label randomized clinical trial BMC psychiatry, 2024
Long-term safety and tolerability of ambrisentan treatment for pediatric patients with pulmonary arterial hypertension: An open-label extension study European journal of pediatrics, 2024
Inhaled treprostinil in pulmonary hypertension associated with COPD: PERFECT study results The European respiratory journal, 2024
Efficacy of testosterone replacement therapy plus alternate-day tadalafil for patients with late-onset hypogonadism: An open-label, randomized, crossover study International journal of urology : official journal of the Japanese Urological Association, 2021
Impact of low-dose tadalafil on adverse events after low-dose-rate brachytherapy for prostate cancer: A bi-center randomized open-label trial International journal of urology : official journal of the Japanese Urological Association, 2021
Adjuvant daily therapy with L-arginine 2,500 mg and tadalafil 5 mg increases efficacy and duration of benefits of low-intensity extracorporeal shock wave therapy for erectile dysfunction: A prospective, randomized, single-blinded study with 1-year follow-up Investigative and clinical urology, 2022
Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo-controlled, three-cycle crossover study in Chinese healthy men Andrology, 2026
Pharmacokinetic Drug Interaction Between Amlodipine and Tadalafil: An Open-Label, Randomized, Multiple-Dose Crossover Study in Healthy Male Volunteers Drug design, development and therapy, 2022
Extracellular Matrix-MYCAF Signatures Correlate with Resistance to Neoadjuvant aPD-L1 Immune Checkpoint Inhibition with Durvalumab + Metformin in HPV+ HNSCC Clinical cancer research : an official journal of the American Association for Cancer Research, 2025
Clinical study of comprehensive TCM therapy in the treatment of damp and hot stasis erectile dysfunction Medicine, 2022
Optimal markers of treatment response to vasodilatory drugs in small vessel disease: An OxHARP trial analysis International journal of stroke : official journal of the International Stroke Society, 2026
A prospective randomized controlled study on scheduled PDE5i and vacuum erectile devices in the treatment of erectile dysfunction after nerve sparing prostatectomy Asian journal of andrology, 2022
A phase 2 randomized, placebo-controlled study on the efficacy and safety of AR1001, a phosphodiesterase-5 inhibitor, in patients with mild-to-moderate Alzheimer's disease The journal of prevention of Alzheimer's disease, 2025
The Cardiorenal Effects of Chronic Phosphodiesterase-V Inhibition in Preclinical Diastolic Dysfunction (Stage B Heart Failure) Journal of cardiac failure, 2023
Comparative study between Tamsulosin, Silodosin and Tadalaﬁl as a medical expulsive therapy for lower ureteral stones Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2023
Shock Wave Therapy in the Treatment of Erection Dysfunction: How to Define Clinical Outcomes? A Comparison Between Penile Doppler Ultrasound and a New Visual Erec-tion Hardness Score (V-EHS) During a Blinded, Sham-Controlled Trial International braz j urol : official journal of the Brazilian Society of Urology, 2025
Long-term tadalafil once daily in Chinese men with erectile dysfunction: a 2-year final analysis of a post-marketing, multicenter, randomized, open-label trial Asian journal of andrology, 2024
Functional outcomes of hypothermic robot assisted radical prostatectomy using BELLOCOOL in a randomized controlled trial Scientific reports, 2025
Bioequivalence and the food effect of macitentan/tadalafil 10/20 fixed-dose combination tablets versus the use of single-component tablets in healthy subjects Pharmacology research & perspectives, 2024
Citrulline Supplementation Improves Microvascular Function and Muscle Strength in Middle-Aged and Older Adults with Type 2 Diabetes Nutrients, 2025
Randomized controlled trial of vericiguat in patients with coronary microvascular dysfunction causing stable chest pain (V-COM): study protocol for a randomized control trial Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2026
L-arginine role for stone lower ureter: A randomized controlled trial Urolithiasis, 2025
The Minimally Important Difference in the Six-minute Walk Test Predicts Clinical Worsening in Pulmonary Arterial Hypertension Respiratory medicine, 2025
Pharmaco-induced erections for penile color-duplex ultrasound: oral PDE5 inhibitors or intracavernosal injection? International journal of impotence research, 2012
Therapeutic effect of tadalafil on lower urinary tract symptoms with erectile dysfunction Zhonghua nan ke xue = National journal of andrology, 2019
Effect on sexual function of a vacuum erection device post-prostatectomy The Canadian journal of urology, 2011
Efficacy and safety of tadalafil 20 mg on demand vs. tadalafil 5 mg once-a-day in the treatment of post-radiotherapy erectile dysfunction in prostate cancer men: a randomized phase II trial The journal of sexual medicine, 2010
Randomized placebo-controlled crossover trial of tadalafil in Raynaud's phenomenon secondary to systemic sclerosis The Journal of rheumatology, 2009
Sexual asthenia: Tradamixina versus Tadalafil 5 mg daily BMC surgery, 2012
Tadalafil 5 mg once daily for the treatment of Asian men with lower urinary tract symptoms secondary to benign prostatic hyperplasia: analyses of data pooled from three randomized, double-blind, placebo-controlled studies International journal of urology : official journal of the Japanese Urological Association, 2015
Treatment of erectile dysfunction reduces psychological distress International journal of andrology, 2009
Treatment satisfaction and clinically meaningful symptom improvement in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia: Secondary results from a 6-month, randomized, double-blind study comparing finasteride plus tadalafil with finasteride plus placebo International journal of urology : official journal of the Japanese Urological Association, 2015
Effects of high altitude exposure on cerebral hemodynamics in normal subjects Stroke, 2005
Sexual function in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia: results of a 6-month, randomized, double-blind, placebo-controlled study of tadalafil coadministered with finasteride The journal of sexual medicine, 2015