Browse studies, page 413
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- Effect of lithium on circadian activity level and flexibility in patients with bipolar disorder: results from the Oxford Lithium Trial EBioMedicine, 2025
- The advantages and limitations of animal models for understanding acute neonatal brain injury Seminars in Perinatology, 2025
- Elucidating the role of probiotics in modulating depression pathophysiology: insights from animal models and clinical trials - a narrative review Food Science and Human Wellness, 2025
- A new module in the drug development process: preclinical multi-center randomized controlled trial of R-ketamine on alcohol relapse Neuropsychopharmacology, 2025
- Animal models of methylmalonic acidemia: insights and challenges Orphanet Journal of Rare Diseases, 2025
- CRISPR-Based Genome Editing in Oral and Maxillofacial Medicine: Bridging in Vitro and Animal Models to Clinical Translation Journal of Lab Animal Research, 2025
- OP41 Duvakitug (TEV-48574), an anti-TL1a monoclonal antibody, demonstrates efficacy and favourable safety as an induction treatment in adults with moderately to severely active ulcerative colitis: Results from a phase 2b, randomised, double-blind, placebo-controlled, dose-ranging, basket trial (RELI Journal of Crohn's & Colitis, 2025
- Impacts of minimally-processed omnivorous vs lacto-ovo-vegetarian diets on insulin sensitivity, lipid profile, and adiposity in older adults: Secondary findings from a randomized crossover feeding trial Clinical Nutrition, 2025
- Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial) medRxiv, 2024
- Anti-fibrosis effect of astragaloside IV in animal models of cardiovascular diseases and its mechanisms: a systematic review Pharmaceutical Biology, 2025
- Animal models in preclinical evaluation of CAR-T cell therapy: Advantages and limitations Biochimica et biophysica acta. Reviews on cancer, 2025
- Can patient-derived in vitro models improve clinical translation in critical care research when used before animal studies? Intensive Care Medicine Experimental, 2025
- Fasting, ketogenic, and anti-inflammatory diets in multiple sclerosis: a randomized controlled trial with 18-month follow-up BMC Nutrition, 2025
- Oxytocin and autism: Insights from clinical trials and animal models Current Opinion in Neurobiology, 2025
- Establishment of a patient-derived 3D in vitro meningioma model in xeno-free hydrogel for clinical applications Acta Neuropathologica Communications, 2025
- Safety and efficacy of atorvastatin for rebleeding in cerebral cavernous malformations (AT CASH EPOC): a phase 1/2a, randomised placebo-controlled trial Lancet Neurology, 2025
- Simulation training of laparoscopic biliary-enteric anastomosis with a three-dimensional-printed model leads to better skill transfer: a randomized controlled trial International Journal of Surgery, 2024
- Natural History of Nipah Virus in Hamsters: Strain, Route, and Sex-Associated Variability Characterized Using Large Datasets to Inform Pre-Clinical Study Design Journal of Infectious Diseases, 2025
- Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: a randomised, double-blind, multicentre, placebo-controlled, phase 2b trial Lancet Neurology, 2025
- Feasibility and safety of dual-console telesurgery with the KangDuo Surgical Robot-1500 System using fifth-generation and wired networks: an animal experiment and sea-spanning clinical study Minerva urology and nephrology, 2024
- Beneficial Effects of Xanthohumol on Metabolic Syndrome: Evidence from In Vitro and Animal Model Studies International Journal of Molecular Sciences, 2024
- Antiviral and immunomodulatory effect of zapnometinib in animal models and hospitalized COVID-19 patients Frontiers in Immunology, 2025
- Sedative and cardiopulmonary effects of medetomidine and butorphanol, with or without vatinoxan, in puppies - randomised, blinded clinical trial Veterinary Anaesthesia and Analgesia, 2026
- The Role of Animal Models in Huntington's Disease Clinical Trials: Decoding Genetic, Non-Genetic, and Molecular Pathways Reviews on recent clinical trials, 2025
- Probiotics and eating disorders: a systematic review of humans and animal model studies Journal of Eating Disorders, 2024
- 780 Targeting myeloid cells with BO-112 engages T cell immunity in combination with radiotherapy and checkpoint blockade in preclinical models and a phase 1 neoadjuvant clinical trial Regular and Young Investigator Award Abstracts, 2024
- First Trial of a Novel Caseous Lymphadenitis Inactivated Vaccine in South Korea: Experimental Evaluation across Various Animal Models Pathogens, 2024
- The Comparative Oncology of Canine Malignant Melanoma in Targeted Therapy: A Systematic Review of In Vitro Experiments and Animal Model Reports International Journal of Molecular Sciences, 2024
- Evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of SM17 in healthy volunteers: results from pre-clinical models and a first-in-human, randomized, double blinded clinical trial Frontiers in Immunology, 2024
- Evaluating the efficacy of the selective orexin 1 receptor antagonist nivasorexant in an animal model of binge-eating disorder International Journal of Eating Disorders, 2024
- Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head Frontiers in Pharmacology, 2025
- Knee osteoarthritis pendulum therapy: In vivo evaluation and a randomised, single-blind feasibility clinical trial Journal of Orthopaedic Translation, 2024
- A phase II trial to evaluate clinical efficacy, pharmacodynamics and exploratory analysis of pemetrexed in relation to MLL4 and UTX alteration status in patients with relapsed/refractory metastatic urothelial carcinoma and other solid tumors Journal of Clinical Oncology, 2025
- Intra- and post-operative analgesic efficacy of a quadratus lumborum block in dogs undergoing elective ovariohysterectomy: a randomized clinical trial Veterinary Anaesthesia and Analgesia, 2025
- A multi-site randomized clinical trial of socially assistive robots on engaging older adults with cognitive impairment residing in long-term care settings: A protocol paper Contemporary Clinical Trials, 2025
- Magnesium microspheres for enhanced transarterial chemoembolization therapy of hepatocellular carcinoma: From animal models to a pilot clinical study Science Advances, 2025
- Antagonizing NRG1-ERBB4 signaling pathway with spironolactone for the treatment of schizophrenia: results of a randomized controlled drug repositioning clinical trial Communications Medicine, 2026
- Artificial intelligence-, organoid-, and organ-on-chip-powered models to improve pre-clinical animal testing of vaccines and immunotherapeutics: potential, progress, and challenges Frontiers Artif. Intell., 2025
- Functional neuroimaging of fatty acid amide hydrolase inhibition in posttraumatic stress disorder: a randomized clinical trial Translational Psychiatry, 2026
- Prospective, randomized, clinical trial on the effects of laparoscopic insufflation pressures on portal pressures in dogs Veterinary surgery, 2024
- Translating Human and Animal Model Studies to Dogs’ and Cats’ Veterinary Care: Beta-Glucans Application for Skin Disease, Osteoarthritis, and Inflammatory Bowel Disease Management Microorganisms, 2024
- Large animal model species in pluripotent stem cell therapy research and development for retinal diseases: a systematic review Frontiers in Ophthalmology, 2024
- A Novel Injectable Polypeptide Nanoparticle Encapsulated siRNA Targeting TGF‐β1 and COX‐2 for Localized Fat Reduction II: Phase I Clinical Trial Journal of Cosmetic Dermatology, 2024
- Safety and immunogenicity of a novel trivalent recombinant MVA-based equine encephalitis virus vaccine: A Phase 1 clinical trial Vaccine, 2024
- A randomized clinical trial evaluating Hydralazine’s efficacy in early-stage Alzheimer’s disease: The EHSAN Study Scientific Reports, 2024
- Assessment of the antileishmanial activity of diallyl sulfide combined with meglumine antimoniate on Leishmania major: Molecular docking, in vitro, and animal model PLoS ONE, 2024
- Topical isoniazid as a novel treatment for melasma: A randomized, double‐blind, vehicle‐controlled clinical trial Journal of Cosmetic Dermatology, 2024
- Neurophysiological effects of a combined treatment of lovastatin and minocycline in patients with fragile X syndrome: Ancillary results of the LOVAMIX randomized clinical trial Autism Research, 2024
- Effects of Satureja Khuzestanica supplementation on glycemic indices and lipid profile in type 2 diabetes patients: a randomized controlled clinical-trial BMC Complementary Medicine and Therapies, 2024
- Meeting the Therapeutic Challenges of Emergent and Rare Invasive Fungal Diseases Through Novel Clinical Trial Designs Open Forum Infectious Diseases, 2024
- Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome Biomedicines, 2025
- Protocol for a randomized placebo-controlled clinical trial using pure palmitoleic acid to ameliorate insulin resistance and lipogenesis in overweight and obese subjects with prediabetes Frontiers in Endocrinology, 2024
- An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease Neurobiology of Disease, 2024
- Polyethylene Glycol–Mediated Axonal Fusion Promotes Early Sensory Recovery after Digital Nerve Injury: A Randomized Clinical Trial Plastic and Reconstructive Surgery, 2024
- Translating medication effects for alcohol use disorder across preclinical, human laboratory, and clinical trial outcomes using meta-analysis Translational Psychiatry, 2025
- The role of neutrophils in vasospasm and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: Is it time for a SAH clinical trial targeting neutrophils? Journal of Cerebral Blood Flow and Metabolism, 2025
- Time-restricted eating in early-stage Huntington’s disease: A 12-week interventional clinical trial protocol PLoS ONE, 2025
- Diet quality, unprocessed plant-based foods, and vascular function in adults with CKD: Secondary analysis of a pilot randomized clinical trial Clinical Nephrology, 2025
- Clinical trial of DprE1 inhibitors: from bench to bedside Discover Applied Sciences, 2025
- The effects of ketogenic metabolic therapy on mental health and metabolic outcomes in schizophrenia and bipolar disorder: a randomized controlled clinical trial protocol Frontiers in Nutrition, 2024
- Effects of Carnosine Supplementation on Cognitive Outcomes in Prediabetes and Well-Controlled Type 2 Diabetes: A Randomised Placebo-Controlled Clinical Trial Pharmaceuticals, 2025
- Ashwagandha (Withania somnifera (L.) Dunal) for promoting recovery in long covid: protocol for a randomised placebo-controlled clinical trial (APRIL Trial) BMJ Open, 2025
- Critical size defect in a rat calvaria model using trephination: An animal model for investigating potential bone regenerative scaffolds MethodsX, 2025
- Vitamin D Supplementation During Neoadjuvant Chemotherapy for Breast Cancer Improves Pathological Complete Response: A Prospective Randomized Clinical Trial World Journal of Surgery, 2025
- Genetic factors associated with reasons for clinical trial stoppage Nature Genetics, 2024
- SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial The Lancet Microbe, 2024
- Low-Frequency Electrical Stimulation of the Auricular Branch of the Vagus Nerve in Patients with ST-Elevation Myocardial Infarction: A Randomized Clinical Trial Journal of Clinical Medicine, 2025
- The 3C (Cell Culture, Computer Simulation, Clinical Trial) Solution for Optimizing the 3R (Replace, Reduction, Refine) Framework during Preclinical Research Involving Laboratory Animals ACS Pharmacology & Translational Science, 2025
- Flaxseed powder supplementation in non-alcoholic fatty liver disease: a randomized controlled clinical trial Food & Function, 2025
- New Productive Force: The Preliminary Report of First Craniofacial Surgical Robot IST Multicenter Clinical Trial in China The Journal of craniofacial surgery (Print), 2024
- Effects of nicotinamide supplementation in normal-tension glaucoma: a crossover placebo-controlled randomised clinical trial British Journal of Ophthalmology, 2025
- Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial Communications Medicine, 2025
- Liraglutide in mild to moderate Alzheimer’s disease: a phase 2b clinical trial Nature Medicine, 2025
- Ultrasound applications in the treatment of major depressive disorder (MDD): A systematic review of techniques and therapeutic potentials in clinical trials and animal model studies Neuromodulation (Malden, Mass.), 2025
- Integration of Clinical Trial Spatial Multi-omics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery Cancer Research, 2024
- RHO-Associated Retinitis Pigmentosa: Genetics, Phenotype, Natural History, Functional Assays, and Animal Model – In Preparation for Clinical Trials Investigative Ophthalmology and Visual Science, 2025
- Preclinical Animal Study and Pilot Clinical Trial of Using Enriched Peripheral Blood-Derived Mononuclear Cells for Intervertebral Disc Degeneration Cell Transplantation, 2024
- Evaluation of clinical efficacy of streptokinase by comparison with the thrombolytic agent on animal model Brazilian journal of biology = Revista brasleira de biologia, 2024
- Moderate static magnetic fields prevent estrogen deficiency-induced bone loss: Evidence from ovariectomized mouse model and small sample size randomized controlled clinical trial PLoS ONE, 2025
- Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials Journal of Robotic Surgery, 2024
- Bioactive Patch for Rotator Cuff Repairing via Enhancing Tendon‐to‐Bone Healing: A Large Animal Study and Short‐Term Outcome of a Clinical Trial Advancement of science, 2024
- Rifaximin reduces gut-derived inflammation in severe acute pancreatitis: an experimental animal model and randomized controlled trial Microbiology spectrum, 2025
- Efficacy of Glycicumarin and Isoliquiritigenin in Suppressing Colonic Peristalsis in Both an Animal Model and a Clinical Trial Biological and Pharmaceutical Bulletin, 2024
- Maintenance Costs, Time, and Efforts Following Implant Therapy With Fixed Restorations Over an Observation Period of 10 Years: A Randomized Controlled Clinical Trial Clinical Implant Dentistry and Related Research, 2024
- Non-surgical treatment of residual periodontal pockets using sodium hypochlorite/amino acid gel and cross-linked hyaluronic acid—a 9-month pilot randomized controlled clinical trial Clinical Oral Investigations, 2024
- Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Journal of Clinical Oncology, 2024
- 10-year follow up of a phase 2 clinical trial of pembrolizumab (pembro) in microsatellite instability-high (MSI-H)/mismatch repair deficient (dMMR) advanced solid tumors Journal of Clinical Oncology, 2025
- Evaluation of Urolithin A Efficacy in Heart Failure Patients with Reduced Ejection Fraction: A Randomized, Double-blind, Crossover, Placebo-controlled Clinical Trial Reviews on recent clinical trials, 2024
- IL-1β, IL-6, TNF- α and CRP in Elderly Patients with Depression or Alzheimer’s disease: Systematic Review and Meta-Analysis Scientific Reports, 2018
- Neoadjuvant FOLFIRINOX in patients with borderline resectable pancreatic cancer: a systematic review and patient-level meta-analysis Journal of the National Cancer Institute, 2019
- Myocardial injury in hospitalized COVID-19 patients: a retrospective study, systematic review, and meta-analysis BMC Cardiovascular Disorders, 2021
- Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes Critical Care, 2020
- Propranolol, chlorpromazine and diclofenac restore susceptibility of extensively drug-resistant (XDR)-Acinetobacter baumannii to fluoroquinolones PLoS ONE, 2020
- Repurposing the anti-breast cancer drug Tamoxifen: antibacterial and antibiofilm efficacy of novel Tamoxifen-AgNP conjugate against multidrug-resistant healthcare-associated pathogens Exploration of Medicine, 2025
- Antibacterial efficacy of Nonea lutea-mediated silver and gold nanoparticles against multidrug-resistant clinical pathogens harboring virulence and resistance genes International Microbiology, 2026
- In vitro efficacy of ceftazidime/avibactam and cefiderocol against multidrug-resistant Gram-negative uropathogens: insights into β-lactamase-mediated resistance in clinical isolates Future Journal of Pharmaceutical Sciences, 2026
- Plasmid Profiles of Multidrug Resistant Uropathogens and Antibacterial Efficacy of Leaf Extracts of Luffa cylindrica International Journal of Research and Innovation in Applied Science, 2026
- Antibacterial and Antibiofilm Efficacy of a Synthetic Nitrofuranyl Pyranopyrimidinone Derivative against Methicillin-Resistant Staphylococcus aureus Journal of Medical Microbiology and Infectious Diseases, 2025
- Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations Journal of Pharmaceutical Analysis, 2014
- To carry out the quality control tests and release studies on different available brands of levofloxacin Asian Journal of Research in Chemistry, 2021