Browse studies, page 227

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• Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans Circulation, 2005
• Propuesta de validación y comparación de dos metodologías analíticas para la cuantificación de sildenafil citrato en tabletas de 50 mg y 100 mg 2019
• The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia Journal of the American College of Cardiology, 2002
• Pharmacological Study of Sildenafil on Healthy Volunteers Clinical and Experimental Pharmacology, 2018
• Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension British Journal of Clinical Pharmacology, 2005
• Kamagra 100 Mg Tablet, Viagra, Sildenafil Citraat Tabletten, Sildenafil Tablet Zenodo (CERN European Organization for Nuclear Research), 2022
• Relative Bioavailability Of Two Sildenafil 100mg Oral Tablet Formulations In Healthy Volunteers Under Fasting Conditions ClinicalTrials.gov · COMPLETED, 2009
• Androgen Modulation of Response to Selective Phosphodiesterase Inhibitors in Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2010
• A Phase 3, Multi-center, Open-label Study To Investigate Safety, Efficacy, And Tolerability Of Sildenafil Citrate In Pediatric Patients With Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2018
• Phase II Study of the Effects of Sildenafil on CFTR-dependent Ion Transport Activity ClinicalTrials.gov · COMPLETED, 2017
• Comparison of Phosphodiesterase-5 Inhibitor and Calcium Channel Inhibitor for the Treatment of Secondary Raynaud Phenomenon, Double Blind, Randomized, Cross-over Trial ClinicalTrials.gov · COMPLETED, 2011
• An Open-Label, Three Period, Fixed Sequence Study to Assess the Effect of a Single Dose of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil in Healthy Subjects Under Fasting Conditions ClinicalTrials.gov · COMPLETED, 2018
• A Phase 3, Multi-Center, Randomized, Double-Blind, Efficacy And Safety Study Of Monotherapy Sitaxsentan Sodium Versus Combination Therapy With Sitaxsentan Sodium And Sildenafil Citrate In Subjects With Pulmonary Arterial Hypertension Who Have Completed Study B1321001 (NCT00795639) ClinicalTrials.gov · TERMINATED, 2011
• Phase 2 Study of Sildenafil for the Treatment of Lymphatic Malformations ClinicalTrials.gov · COMPLETED, 2021
• The Effect of the Selective PDE5 Inhibitor, Sildenafil, on Aura and Migraine Headache Induction ClinicalTrials.gov · COMPLETED, 2021
• A Multicenter, Open Label, High Dose (100mg) Rapid Titration Study, To Evaluate The Efficacy And Satisfaction Of Patrex® (Sildenafil Citrate) In Men With Erectile Dysfunction In Mexico ClinicalTrials.gov · COMPLETED, 2008
• Multicenter Randomized Double-Blind, Placebo-Controlled, Fixed-Dose Parallel Study Of Men With Mild To Moderate Erectile Dysfunction To Evaluate The Efficacy Of Viagra 8 Hours Post-Dose - II ClinicalTrials.gov · COMPLETED, 2006
• Phase 1 Study of Sildenafil (Viagra) Treatment of Subacute Ischemic Stroke ClinicalTrials.gov · TERMINATED
• The Effect of Sildenafil and Tadalafil on Skeletal Muscle and Perceptual Fatigue ClinicalTrials.gov · COMPLETED, 2015
• Phase 4 Study of the Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With Chronic Fatigue Syndrome ClinicalTrials.gov · COMPLETED, 2010
• A Double Blind, Randomized, Placebo Controlled, Two Part, Two Session Balanced, Crossover Study to Evaluate Visual Changes in Healthy Male Subjects Aged 18 - 55 Years After Receiving: 1. at Least 15 Doses of 20 mg Vardenafil, Compared to Placebo and 2. Two Doses of Sildenafil, 200 mg Compared to Placebo ClinicalTrials.gov · COMPLETED, 2006
• A Phase 1, Open Label, Randomized, Four Period, Crossover, Multiple Dose Study To Assess The Pharmacokinetic Interaction Between Sitaxsentan and Tadalafil and The Effect Of Sildenafil On Sitaxsentan PK In Healthy Subjects ClinicalTrials.gov · TERMINATED, 2010
• A Relative Bioavailability Study Between Two Formulations Of Sildenafil Citrate In Healthy Male Subjects, Fasting Dosing, Being The Test Formulation Sildenafil Citrate 100 Mg CT , And The Reference Formulation Sildenafil Citrate 100 Mg Film-Coated Tablets (Viagra®), Both Formulations Manufactured By Laboratórios Pfizer Ltda ClinicalTrials.gov · COMPLETED, 2010
• A Multicenter, Long-Term Extension Study to Assess Safety of Oral Sildenafil Citrate In The Treatment Of Subjects Who Have Completed Study A1481131 ClinicalTrials.gov · COMPLETED, 2012
• A 2-Cohort, Multi-Centre, Randomised, Double Blind, Placebo Controlled 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses Of PF-00446687 On Erectile Function In Men Suffering From Erectile Dysfunction, Using 100 Mg Sildenafil As A Positive Control ClinicalTrials.gov · COMPLETED, 2008
• Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis ClinicalTrials.gov · COMPLETED, 2009
• Sildenafil Citrate in the Treatment of Primary Dysmenorrhea ClinicalTrials.gov · COMPLETED, 2011
• Cardiovascular Effects of Chronic Sildenafil (Viagra) Treatment in Diabetic Subjects With Endothelial Dysfunction ClinicalTrials.gov · COMPLETED, 2009
• A Double Blind, Placebo Controlled 2-way Cross-over Study to Assess the Clitoral Engorgement Response as Measured by Non-contrast Magnetic Resonance Imaging (MRI) in Women With Female Sexual Arousal Disorder (FSAD) When Administered a Single Dose of Sildenafil (100mg) Followed by Audio/Visual Sexual Stimulation ClinicalTrials.gov · COMPLETED, 2007
• Evaluation of Systemic and Penile Microvascular Endothelial Function and Arterial Pressure After Chronic Administration of Sildenafil in Hypertensive Men With Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2018
• A Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of the Addition of Inhaled Iloprost in Patients With Pulmonary Arterial Hypertension Receiving Oral Sildenafil ClinicalTrials.gov · TERMINATED, 2008
• The Effect of Sildenafil Citrate on the Success Rate of Ovulation Induction Using Clomiphene: A Randomized Controlled Trial ClinicalTrials.gov · COMPLETED, 2017
• Mechanisms of Exercise Intolerance in Cystic Fibrosis: Role of PDE5 Inhibition ClinicalTrials.gov · COMPLETED, 2024
• A Phase 1, Placebo Controlled, Blinded, Multiple Dose Escalation Study of AIR001 (Sodium Nitrite Inhalation Solution) in Healthy Subjects, an Assessment of the Tolerability in Combination With Oral Sildenafil, and an Open-Label Study of Multiple Dose AIR001 in Patients With Pulmonary Arterial Hypertension ClinicalTrials.gov · COMPLETED, 2012
• Effect of Adding Sildenafil to Protocol of Endometrial Preparation in Outcome of Frozen-thawed Embryo Transfer Cycles ClinicalTrials.gov · COMPLETED, 2011
• Multicenter, Double-Blind, Randomized, Placebo-controlled Study of Flexible, Titration Dose Administered on an As Needed Basis (PRN) to Evaluate the Efficacy and the Safety of Sildenafil for the Treatment of Erectile Dysfunction in Male Patients on Hemodialysis ClinicalTrials.gov · COMPLETED, 2005
• The Pathophysiology and Treatment of Supine Hypertension in Patients With Autonomic Failure ClinicalTrials.gov · COMPLETED, 2017
• A Placebo-Controlled Single-Dose Trial of Sildenafil in Schizophrenia ClinicalTrials.gov · COMPLETED, 2008
• An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus) ClinicalTrials.gov · COMPLETED, 2006
• A Multicenter, Randomized, Parallel Group, Double-Blind, Placebo Controlled, Flexible Dose Escalation Study To Evaluate Sexual And Relationship Satisfaction In The Female Partner Of Men With Erectile Dysfunction Treated With Viagra (Sildenafil Citrate) In The United States ClinicalTrials.gov · COMPLETED, 2004
• A Phase 2a, Randomized, Double Blind, Placebo-controlled, Parallel Group Study Investigating The Dose-response Of Pf-00489791 On Acute Hemodynamics In Subjects With Idiopathic And Familial Pulmonary Arterial Hypertension ClinicalTrials.gov · TERMINATED, 2010
• An Open-Label, Multi-Center Extension Study To Evaluate The Safety, Toleration And Sustained Efficacy Of Oral Sildenafil Administered To Women Who Have Been Diagnosed With Female Sexual Arousal Disorder ClinicalTrials.gov · COMPLETED, 2004
• Oral Sildenafil in Persistent Pulmonary Hypertension of Neonates Secondary to Meconium Aspiration Syndrome: A Randomized Placebo Controlled Trial ClinicalTrials.gov · COMPLETED, 2012
• Efficacy of Testosterone Replacement Therapy in Penile Rehabilitation Following Radical Prostatectomy (#: 04-07-30-01) ClinicalTrials.gov · TERMINATED, 2013
• A Phase 3, Multi-Center, Open Label Study To Evaluate The Long-Term Safety Of Monotherapy Sitaxsentan Sodium And Combination Therapy With Sitaxsentan Sodium And Sildenafil Citrate In Subjects With Pulmonary Arterial Hypertension ClinicalTrials.gov · TERMINATED, 2011
• Multicenter, Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose Parallel Study of Men With Mild to Moderate Erectile Dysfunction to Evaluate the Efficacy of Viagra 8 Hours Post-Dose ClinicalTrials.gov · COMPLETED, 2006
• Effect of Sildenafil Vaginal Gel Co-treatment With Clomiphene Citrate on Endometrial Thickness in Infertile Women With Prior Clomiphene Citrate Failure Due to Thin Endometrium: a Prospective Self-controlled Clinical Trial ClinicalTrials.gov · COMPLETED, 2016
• Effects of Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Morbidity and Mortality in Symptomatic Patients With Pulmonary Arterial Hypertension - A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group, Prospective, Event Driven Phase IV Study ClinicalTrials.gov · COMPLETED, 2013
• Treatment Of Erectile Dysfunction In Patients Treated On RTOG-9910 For Prostate Cancer: Impact On Patient And Partner Quality Of Life ClinicalTrials.gov · COMPLETED
• Effect of Oral Sildenafil With Digital Therapeutic Iontophoresis of Sodium Nitroprussiate on Cutaneous Blood Flow in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2011
• Impact of Tadalafil (LY450190) Once a Day or Tadalafil on Demand Compared to Sildenafil Citrate on Demand on Treatment Discontinuation in Patients With Erectile Dysfunction Who Are naïve to PDE5 Inhibitors ClinicalTrials.gov · COMPLETED, 2011
• Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis ClinicalTrials.gov · TERMINATED, 2016
• A Double-blind, Placebo-controlled, Randomized, 2-way Crossover Study to Investigate the Hemodynamic Effects of a Single Dose of Sildenafil (100mg) in Subjects With Benign Prostatic Hyperplasia Being Treated With Doxazosin ClinicalTrials.gov · COMPLETED, 2003
• The Use and Efficacy of Sildenafil in Diabetic Men With Erectile Dysfunction: the Impact on Endothelial Function, a Pilot Feasibility Study ClinicalTrials.gov · COMPLETED, 2007
• An Open-label, International, Multicenter, Single-arm, Uncontrolled, Phase IIIb Study of Riociguat in Patients With Pulmonary Arterial Hypertension (PAH) Who Demonstrate an Insufficient Response to Treatment With Phosphodiesterase-5 Inhibitors (PDE-5i) ClinicalTrials.gov · COMPLETED, 2016
• A Phase 2a, Single-Dose, Double-Blind, Placebo-Controlled, 2-Way Crossover Study to Evaluate the Efficacy and Safety of SST-6006 Compared to Placebo in the Treatment of Erectile Dysfunction ClinicalTrials.gov · COMPLETED, 2017
• Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1 ClinicalTrials.gov · TERMINATED, 2021
• Efficacy of Intracavernosal (Xeomin®) 100U as add-on Therapy to Sildenafil 100 mg on Demand Compared to Sildenafil 100 mg on Demand for the Treatment of Erectile Dysfunction (ED) Not Sufficiently Responsive to Standard Therapy With Phosphodiesterase Type 5 Inhibitors ClinicalTrials.gov · COMPLETED, 2024
• An Open-Label, Long-Term Study of Ambrisentan in Pulmonary Hypertension Subjects Having Completed Myogen Study AMB-220 ClinicalTrials.gov · COMPLETED, 2009
• Phase 1/2 open-label study of PF-06747775 (epidermal growth factor receptor T790M inhibitor) in patients with advanced epidermal growth factor receptor mutant (DEL 19 or L858R ± T790M) NON-small cell lung cancer ClinicalTrials.gov · TERMINATED, 2020
• Evaluation and Validation of Metabolic Markers for the Prediction of Drug-drug Interaction of Various CYP3A4 Substrates and Inhibitors in Healthy Male Subjects ClinicalTrials.gov · COMPLETED, 2017
• Evaluation of the effect of sildenafil on the microvascular blood flow in patients with systemic sclerosis: a randomised, double-blind, placebo-controlled study Clinical and Experimental Rheumatology, 2017
• Effects of sildenafil citrate on pancreatic and lung complications in an experimental L-arginine-induced acute pancreatitis model Gastroenterology Review, 2021
• Effect of sildenafil citrate on prediabetic and diabetic albino rats treated with metformin 2021
• Adding sildenafil vaginal gel to clomiphene citrate in infertile women with prior clomiphene citrate failure due to thin endometrium: a prospective self-controlled clinical trial Facts, views & vision in ObGyn, 2017
• Investigation of distinct molecular pathways in migraine induction using calcitonin gene-related peptide and sildenafil Cephalalgia, 2019
• The potential beneficial effects of sildenafil and diosmin in experimentally-induced gastric ulcer in rats Heliyon, 2020
• Cavernous artery intima‐media thickness predicts the response to sildenafil in erectile dysfunction patients as a morphological parameter Andrologia, 2021
• The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects Drug Metabolism and Pharmacokinetics, 2020
• Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding BioMed Research International, 2018
• Comparison of the efficacy and safety of low-intensity extracorporeal shock wave therapy versus on-demand sildenafil for erectile dysfunction Translational Andrology and Urology, 2021
• The Effect of Vaginal Sildenafil on The Outcome of Assisted Reproductive Technology Cycles in Patients with Repeated Implantation Failures: A Randomized Placebo-Controlled Trial International Journal of Fertility and Sterility, 2019
• Effects of sildenafil on inflammatory injury of the lung in sodium taurocholate-induced severe acute pancreatitis rats International Immunopharmacology, 2020
• Ocular Side Effects of Sildenafil That Persist Beyond 24 h-A Case Series Frontiers in Neurology, 2020
• Sildenafil in Emergency Treatment of Biliary Colic: A pilot randomized controlled trial medRxiv, 2022
• Inefficacy of Sildenafil treatment of idiopathic pulmonary hypertension Bulletin of the Academy of Sciences of Moldova. Medical Sciences, 2022
• Diosmin enhances the anti-angiogenic activity of sildenafil and pentoxifylline against hepatopulmonary syndrome via regulation of TNF-α/VEGF, IGF-1/PI3K/AKT, and FGF-1/ANG-2 signaling pathways European Journal of Pharmacology, 2020
• Design of a randomised, double-blind, crossover, placebo-controlled trial of effects of sildenafil on cerebrovascular function in small vessel disease: Oxford haemodynamic adaptation to reduce pulsatility trial (OxHARP) European Stroke Journal, 2021
• Effects of a conventional aphrodisiac: a twenty eight day repeated administration of Sildenafil citrate graded doses on experimental rats Dutse Journal of Pure and Applied Sciences, 2022
• The headache and aura-inducing effects of sildenafil in patients with migraine with aura Cephalalgia, 2022
• Method suitability validation for determination of microbiological purity of Sildenafil film-coated tablet Macedonian Pharmaceutical Bulletin, 2023
• Effect of combining estradiol valerate with sildenafil in increasing the thickness of the endometrium in infertile women before intrauterine insemination: a randomized clinical trial International Journal of Basic & Clinical Pharmacology, 2023
• The Effect of Sildenafil Citrate (Viagra®) on Nasal Olfactory Mucosa of Adult Male Albino Rat: caspase-3 and inducible nitric oxide synthase protein expressions Catrina The International Journal of Environmental Sciences, 2023
• The Treatment Satisfaction in Patients and Their Partners Treated with Low-Intensity Extracorporeal Shock Wave Therapy and Sildenafil: A Prospective Non-Randomized Controlled Study Patient Preference and Adherence, 2023
• Evaluation of the Influence of Sildenafil on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Vericiguat in Healthy Adults Clinical Pharmacokinetics, 2023
• Treating erectile dysfunction with sildenafil alone versus combined with vitamin D3 in patients with low serum 25-hydroxy vitamin D3: a prospective randomized controlled open trial Journal of Men's Health, 2023
• Hepatotoxic Effects of Sildenafil Adulterated Herbal Aphrodisiacs (Attoté and Congnons-moussos), Following Chronic Exposure in Male Wistar Rats Toxicology International, 2026
• Sildenafil and metformin combination attenuates monocrotaline-induced pulmonary hypertension via TNF-α and ERK1/2 modulation Journal of Pharmacy & Pharmacognosy Research, 2026
• Targeted market survey of undeclared sildenafil in high-risk sexual enhancement supplements marketed in Hungary Journal of Consumer Protection and Food Safety, 2026
• Evaluation of sildenafil citrate effect on semen parameters, testosterone, insulin like-3 and inhibin-b levels Egyptian Journal of Dermatology and Venereology, 2026
• Design and evaluation of bilayer sildenafil sublingual tablets combining fast-dispersible and mucoadhesive layers Science, Engineering and Health Studies, 2026
• Long-term exposure to sildenafil-adulterated herbal aphrodisiacs induces oxidative and functional alterations in the prostate and seminal vesicles of male rats International Journal of Research in Pharmaceutical Sciences, 2025
• Clinical application of prognostic factors for patients with organic causes of erectile dysfunction on 100 mg of sildenafil citrate International journal of urology, 2004
• Hardness, function, emotional well-being, satisfaction and the overall sexual experience in men using 100-mg fixed-dose or flexible-dose sildenafil citrate International journal of impotence research, 2010
• Efficacy, tolerability and satisfaction with sildenafil citrate 100‐mg titration compared with continued 50‐mg dose treatment in men with erectile dysfunction BJU International, 2008
• Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt Journal of Sexual Medicine, 2009
• Improvement in erection hardness and intercourse success with first dose of sildenafil citrate 100 mg International Journal of General Medicine, 2013
• Cavernous tissue rehabilitation whit sildenafil 100 mg in patients after radical prostatectomy Actas Urológicas Españolas, 2009
• Relative Bioavailability of Chewable and Conventional Film-Coated Tablet Formulations of Sildenafil 100 mg in Healthy Volunteers Under Fasting Conditions Journal of Bioequivalence & Bioavailability, 2011
• Re: Erectile function, erection hardness and tolerability in men treated with sildenafil 100 mg vs. 50 mg for erectile dysfunction Journal of Urology, 2014