Browse studies, page 939

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• Peri-intubation complications in critically ill obese patients: a secondary analysis of the international INTUBE cohort Critical Care, 2025
• Effectiveness of repeated Esketamine nasal spray administration on anhedonic symptoms in treatment-resistant bipolar and unipolar depression: A secondary analysis from the REAL-ESK study group Psychiatry Research, 2025
• Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis Diabetes Care, 2025
• Exercise adherence is associated with improvements in pain intensity and functional limitations in adults with chronic non-specific low back pain: a secondary analysis of a Cochrane review Journal of Physiotherapy, 2025
• Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study Annals of Intensive Care, 2025
• Impact of CFTR Modulators on Longitudinal Cystic Fibrosis Survival and Mortality: Review and Secondary Analysis Pulmonary Therapy, 2025
• ctDNA and Recurrence Risk for Adjuvant De-Escalation in HPV-Positive Oropharyngeal Carcinoma: A Secondary Analysis of the DART Phase 3 Randomized Clinical Trial JAMA Otolaryngology - Head and Neck Surgery, 2025
• Identification of key factors related to digital health observational study adherence and retention by data-driven approaches: an exploratory secondary analysis of two prospective longitudinal studies The Lancet Digital Health, 2025
• Associations between moderate-to-vigorous physical activity, p-tau181, and cognition in healthy older adults with memory complaints: a secondary analysis from the MAPT. The Lancet Healthy Longevity, 2025
• Active Monitoring, Surgery, and Radiotherapy for Cribriform-Positive and Cribriform-Negative Prostate Cancer: A Secondary Analysis of the PROTECT Randomized Clinical Trial JAMA Oncology, 2025
• Effects of Resmetirom on Metabolic‐Dysfunction Associated Steatohepatitis in Patients With Weight Loss and/or Diabetes Taking Glucagon‐Like Peptide‐1 Receptor Agonists and Other Diabetes Therapies: A Secondary Analysis of the MAESTRO‐NASH Trial Alimentary Pharmacology and Therapeutics, 2025
• The Impact of an Adaptive mHealth Intervention on Improving Patient-Provider Health Care Communication: Secondary Analysis of the DIAMANTE Trial JMIR mHealth and uHealth, 2025
• Menopausal Hormone Therapy and Cardiovascular Diseases in Women With Vasomotor Symptoms: A Secondary Analysis of the Women's Health Initiative Randomized Clinical Trials JAMA Internal Medicine, 2025
• Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007–2023: a systematic review and secondary analysis The Lancet Regional Health - Europe, 2025
• Prices, availability, and affordability of adult medicines in 54 low-income and middle-income countries: evidence based on a secondary analysis Lancet Global Health, 2025
• Dynamic association of serum albumin changes with inflammation, nutritional status and clinical outcomes: a secondary analysis of a large prospective observational cohort study European Journal of Medical Research, 2025
• A Feasibility Open-Labeled Clinical Trial Using a Second-Generation Artificial-Intelligence-Based Therapeutic Regimen in Patients with Gaucher Disease Treated with Enzyme Replacement Therapy Journal of Clinical Medicine, 2024
• The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial Clinical Oral Investigations, 2024
• Real-World and Clinical Trial Validation of a Deep Learning Radiomic Biomarker for PD-(L)1 Immune Checkpoint Inhibitor Response in Advanced Non–Small Cell Lung Cancer JCO Clinical Cancer Informatics, 2024
• The efficacy of reconstructive therapy in the surgical management of peri-implantitis: A 3-year follow-up of a randomized clinical trial Journal of Clinical Periodontology, 2024
• Effects of Silybum marianum, Pueraria lobate, combined with Salvia miltiorrhiza tablets on non-alcoholic fatty liver disease in adults: A triple-blind, randomized, placebo-controlled clinical trial Clinical Nutrition ESPEN, 2024
• Adaptive phase I-II clinical trial designs identifying optimal biological doses for targeted agents and immunotherapies Clinical Trials, 2024
• Using multistate models with clinical trial data for a deeper understanding of complex disease processes Clinical Trials, 2024
• Ecological momentary assessment and cue-elicited drug craving as primary endpoints: study protocol for a randomized, double-blind, placebo-controlled clinical trial testing the efficacy of a GLP-1 receptor agonist in opioid use disorder Addiction Science & Clinical Practice, 2024
• Phase I clinical trial of MUC1-targeted CAR-T cells with PD-1-knockout in the treatment of advanced breast cancer Journal of Clinical Oncology, 2024
• A High Omega-3, Low Omega-6 Diet with Fish Oil for Men with Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial Journal of Clinical Oncology, 2024
• Efficacy and Safety of Brodalumab, an Anti-interleukin-17 Receptor A Monoclonal Antibody, for Palmoplantar Pustulosis: 16-Week Results of a Randomized Clinical Trial American Journal of Clinical Dermatology, 2024
• Radiation therapy with or without cisplatin for local recurrences of endometrial cancer: Results from an NRG Oncology/GOG prospective randomized multi-center clinical trial Journal of Clinical Oncology, 2024
• First-Line Anlotinib Treatment for Soft-Tissue Sarcoma in Chemotherapy-Ineligible Patients: An Open-Label, Single-Arm, Phase 2 Clinical Trial Clinical Cancer Research, 2024
• Fixed Full-Arch Maxillary Prostheses Supported by Four Versus Six Implants: 5-Year Results of a Multicenter Randomized Clinical Trial Clinical Oral Implants Research, 2024
• Update on Clinical Trial Endpoints in Gene Therapy Trials for Inherited Retinal Diseases Journal of Clinical Medicine, 2024
• Accuracy of navigation guided implant surgery for immediate loading complete arch restorations: Prospective clinical trial Clinical Implant Dentistry and Related Research, 2024
• Sodium benzoate, a D‐amino acid oxidase inhibitor, improved short‐term memory in patients with mild cognitive impairment in a randomized, double‐blind, placebo‐controlled clinical trial Psychiatry and Clinical Neurosciences, 2025
• Effect of 1-year lifestyle intervention with energy-reduced Mediterranean diet and physical activity promotion on the gut metabolome and microbiota: a randomized clinical trial American Journal of Clinical Nutrition, 2024
• Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program American Journal of Clinical Dermatology, 2024
• Non‐Surgical Treatment of Moderate Periodontal Intrabony Defects With Adjunctive Cross‐Linked Hyaluronic Acid: A Single‐Blinded Randomized Controlled Clinical Trial Journal of Clinical Periodontology, 2024
• Influences on clinical trial participation: Enhancing recruitment through a gender lens - A scoping review Contemporary Clinical Trials Communications, 2024
• Linking clinical trial participants to their U.S. real-world data through tokenization: A practical guide Contemporary Clinical Trials Communications, 2024
• A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma Clinical Cancer Research, 2024
• Asia‐Inclusive Global Development of Enpatoran: Results of an Ethno‐Bridging Study, Intrinsic/Extrinsic Factor Assessments and Disease Trajectory Modeling to Inform Design of a Phase II Multiregional Clinical Trial Clinical pharmacology and therapy, 2024
• Molnupiravir clinical trial simulation suggests that polymerase chain reaction underestimates antiviral potency against SARS-CoV-2 Journal of Clinical Investigation, 2025
• Feet Cooling As a Preventive Strategy against Chemotherapy-Induced Peripheral Neuropathy in Advanced Breast Cancer Patients: A Randomized Clinical Trial Clinical Breast Cancer, 2025
• Arginine Dentifrices and Childhood Caries Prevention: A Randomized Clinical Trial JDR Clinical & Translational Research, 2025
• Early periodontal wound healing after chlorhexidine rinsing: a randomized clinical trial Clinical Oral Investigations, 2024
• Effectiveness and Safety of Varying Doses of Linezolid With Bedaquiline and Pretomanid in Treatment of Drug-Resistant Pulmonary Tuberculosis: Open-Label, Randomized Clinical Trial Clinical Infectious Diseases, 2024
• Verification of molecular subtyping of bladder cancer in the GUSTO clinical trial The Journal of Pathology: Clinical Research, 2024
• Phase 2b randomized clinical trial of amlitelimab, an anti-OX40 ligand antibody, in patients with moderate-to-severe atopic dermatitis Journal of Allergy and Clinical Immunology, 2024
• Sinus Floor Elevation With Platelet‐Rich Fibrin From Horizontal Centrifugation and Xenograft: Randomized Clinical Trial Clinical Implant Dentistry and Related Research, 2025
• How Does Anterior Vertebral Body Tethering Compare to Posterior Spinal Fusion for Thoracic Idiopathic Scoliosis? A Nonrandomized Clinical Trial Clinical Orthopaedics and Related Research, 2025
• The Effect of Osseodensification on Implant Stability and Marginal Bone Levels: A Randomized Control Clinical Trial Clinical and Experimental Dental Research, 2025
• Epidural Stimulation and Resistance Training (REST-SCI) for Overground Locomotion After Spinal Cord Injury: Randomized Clinical Trial Protocol Journal of Clinical Medicine, 2025
• Cannabidiol Intervention for Muscular Tension, Pain, and Sleep Bruxism Intensity—A Randomized, Double-Blind Clinical Trial Journal of Clinical Medicine, 2024
• Comparative analysis of dental implant placement accuracy: Semi‐active robotic versus free‐hand techniques: A randomized controlled clinical trial Clinical Implant Dentistry and Related Research, 2024
• Double-blinded, randomized clinical trial of Gegen Qinlian decoction pinpoints Faecalibacterium as key gut bacteria in alleviating hyperglycemia Precision Clinical Medicine, 2024
• HER2 heterogeneity and treatment response–associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial Journal of Clinical Investigation, 2024
• Riluzole in Combination with mFOLFOX6 and Bevacizumab in Treating Patients with Metastatic Colorectal Cancer: A Phase 1 Clinical Trial Clinical Cancer Research, 2025
• Ultrasound-guided paravertebral block with liposomal bupivacaine vs. non-liposomal bupivacaine for postoperative pain control after the Nuss procedure in children: A randomized clinical trial Journal of clinical anesthesia, 2025
• Enhanced Palatal Wound Healing with Leucocyte- and Platelet-Rich Fibrin After Free Gingival Graft Harvesting: A Prospective Randomized Controlled Clinical Trial Journal of Clinical Medicine, 2025
• Recruiting and Consenting Decentralized Clinical Trial Participants—Learnings from the Trials@Home RADIAL Proof‐of‐Concept Trial Clinical pharmacology and therapy, 2025
• A Randomized Controlled Clinical Trial Testing Effects of Lademirsen on Kidney Function Decline in Adults with Alport Syndrome American Society of Nephrology. Clinical Journal, 2024
• Evaluation of the Effectiveness of a Mouthwash Containing Spilanthol and Cannabidiol on Improving Oral Health in Patients with Gingivitis—Clinical Trial Journal of Clinical Medicine, 2025
• Exebacase in Addition to Standard-of-Care Antibiotics for Staphylococcus aureus Bloodstream Infections and Right-Sided Infective Endocarditis: A Phase 3, Superiority-Design, Placebo-Controlled, Randomized Clinical Trial (DISRUPT) Clinical Infectious Diseases, 2024
• Large Language Models for Clinical Trial Protocol Assessments Clinical pharmacology and therapy, 2025
• Circulating microRNA analysis in a prospective co-clinical trial identifies MIR652-3p as a response biomarker and driver of regorafenib resistance mechanisms in colorectal cancer Clinical Cancer Research, 2024
• The Accuracy of Autonomous Robotic Surgery vs. Dynamic Navigation in Implant Placement: An Open-Label, Double-Arm, Randomized Controlled Clinical Trial Clinical Oral Implants Research, 2025
• Spatial transcriptomics advances the use of canine patients in cancer research: analysis of osteosarcoma-bearing pet dogs enrolled in a clinical trial Clinical Cancer Research, 2025
• Impact of Multimedia Information on Patients' Knowledge, Anxiety and Decision-Making Regarding Computer-Assisted and Freehand Dental Implant Surgery: A Randomised Clinical Trial Clinical Oral Implants Research, 2025
• Zirconia-reinforced glass ionomer restorations in molar incisor hypomineralization: a randomized controlled clinical trial Clinical Oral Investigations, 2025
• A Phase II Clinical Trial of Neoadjuvant Concurrent Chemoradiotherapy for Locally Advanced High-Grade Thymic Tumors JTO Clinical and Research Reports, 2025
• Leveraging Artificial Intelligence for Data Integrity, Transparency, and Security in Technology-enabled Improvements to Clinical Trial Data Management in Healthcare Reviews on recent clinical trials, 2025
• Implant stability in the posterior maxilla: clinical and radiographic comparison of osseodensification and conventional drilling: a randomized clinical trial Clinical Oral Investigations, 2025
• Alternate-day fasting elicits larger changes in fat mass than time-restricted eating in adults without obesity - A randomized clinical trial Clinical Nutrition, 2025
• Brexpiprazole in Combination With Sertraline and as Monotherapy in Posttraumatic Stress Disorder: A Full-Factorial Randomized Clinical Trial Journal of Clinical Psychiatry, 2025
• Chairside vs Prefabricated Sealing Socket Abutments for Posterior Immediate Implants: A Randomized Clinical Trial Clinical Implant Dentistry and Related Research, 2025
• Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity: A randomized clinical trial Clinical Nutrition, 2024
• Increasing acceptance of AI‐generated digital twins through clinical trial applications Clinical and Translational Science, 2024
• Complication, vertical bone gain, volumetric changes after vertical ridge augmentation using customized reinforced PTFE mesh or Ti‐mesh. A non‐inferiority randomized clinical trial Clinical Oral Implants Research, 2024
• Cross‐Linked Volume‐Stable Collagen Matrix Versus Connective Tissue Graft for Soft Tissue Augmentation at Implant Site. A Non‐Inferiority, Multicenter Randomized Clinical Trial Clinical Oral Implants Research, 2025
• Effectiveness of hypotension prediction index software in reducing intraoperative hypotension in prolonged prone-position spine surgery: a single-center clinical trial Journal of clinical monitoring and computing, 2025
• National Cancer Institute’s Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations Journal of Clinical Oncology, 2025
• Evaluating re-identification risks scores in publicly available clinical trial datasets: Insights and implications Clinical Trials, 2025
• Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: a triple-blind randomized clinical trial Clinical Oral Investigations, 2025
• Personalized Cancer Vaccines in the Clinical Trial Pipeline Asia-Pacific Journal of Clinical Oncology, 2025
• Efficacy and Safety of BL-B01D1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma: A Phase II Clinical Trial Journal of Clinical Oncology, 2025
• Motivation to Clinical Trial Participation: Health Information Distrust and Healthcare Access as Explanatory Variables and Gender as Moderator Journal of Clinical Medicine, 2025
• Efficacy of Lapatinib in Patients with HER2-Negative Metastatic Breast Cancer and HER2-Positive Circulating Tumor Cells-The DETECT III Clinical Trial Clinical Chemistry, 2024
• A phase III randomized clinical trial evaluating perioperative therapy (neoadjuvant chemotherapy versus chemoradiotherapy) in locally advanced gallbladder cancers (POLCAGB) Journal of Clinical Oncology, 2025
• Effect of vitamin D supplementation on glycemic control in children and adolescents with type 1 diabetes mellitus: Data from a controlled clinical trial Diabetes Research and Clinical Practice, 2025
• Second‐Generation (44‐Channel) Suprachoroidal Retinal Prosthesis: Surgical Stability and Safety During a 2‐Year Clinical Trial Clinical and Experimental Ophthalmology, 2025
• The Efficacy of Left Atrial vs Biatrial Cardioneuroablation in Patients With Vasovagal Syncope: A Randomized Clinical Trial JACC Clinical Electrophysiology, 2025
• Final Results From the Randomized Phase III ASCENT Clinical Trial in Metastatic Triple-Negative Breast Cancer and Association of Outcomes by Human Epidermal Growth Factor Receptor 2 and Trophoblast Cell Surface Antigen 2 Expression Journal of Clinical Oncology, 2024
• A multicenter prospective clinical trial reveals cell-free DNA methylation markers for early esophageal cancer Journal of Clinical Investigation, 2025
• First-in-Human clinical trial of a small molecule EBNA1 inhibitor, VK-2019, in patients with Epstein-Barr positive nasopharyngeal cancer, with pharmacokinetic and pharmacodynamic studies Clinical Cancer Research, 2025
• Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial Journal of Clinical Oncology, 2025
• Effects of multi-strain probiotics supplementation on body adiposity and metabolic profile in individuals with hypertension and overweight following an energy-restricted diet: A randomized clinical trial Clinical Nutrition, 2025
• Disease classification, diagnostic challenges, and evolving clinical trial design in MASLD Journal of Clinical Investigation, 2025
• Dual Immune Check Point Blockade in MGMT-Unmethylated Newly Diagnosed Glioblastoma: NRG Oncology BN007, a Randomized Phase II/III Clinical Trial Journal of Clinical Oncology, 2025
• Sequential Infusion of Mesenchymal Stem Cell for Graft-Versus-Host Disease Prevention in Haploidentical Hematopoietic Stem Cell Transplantation: An Open-Label, Multicenter, Randomized Controlled Clinical Trial Journal of Clinical Oncology, 2025
• Milademetan in Advanced Solid Tumors with MDM2 Amplification and Wild-type TP53: Preclinical and Phase II Clinical Trial Results Clinical Cancer Research, 2025
• Effect of Nonsurgical Mechanical Debridement With or Without Chlorhexidine Formulations in the Treatment of Peri‐Implant Mucositis. A Randomized Placebo‐Controlled Clinical Trial Clinical Oral Implants Research, 2025